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Ok, I see the doc tomorrow and I def want to up the Paxil. I'm at 40 mg so I really don't know if a increase will do any good.

 

Like I have said...I was traumatized by my psychosis.....Thinking the jail was a human meat market and it was the end times and cannibals and zombies where real.....Actually thinking there real mean there real in my book. Not technically but, ya know. Anyways I heard prozasin showed Vets benefits during treatment of it with nightmares. I'm telling you seeing the same thing in my head for years while asleep gets to you.....

 

 

 

I would like to hear experiences with prozasin and a higher dosage of Paxil if anyone is up for it.

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Sonic- I only take 40 mg of Paxil, but do take Prazosin 1 mg at bedtime.  It is amazing for me!!!!!  No nightmares and NO side effects.  It is an anti-hypertensive, but did not affect my blood pressure.  Good luck with the Prazosin!

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Prazosin is fantastic! I started taking it a couple months ago. It's helped my nightmares so very much. I was on 60 mg of Paxil at one point. Helped with my panic disorder and anxiety.

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Well I got the prazosin and I was wondering if there are any real differences between inderal and prazosin. I hope there are because inderal never helped my nightmares.

 

They are different classes of medication so you can't gauge how you will react to parzosin by your reaction to Inderal.

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Did it just ease your nightmares to where when you woke up you could deal with life better or did it take them away?

For me, I either don't have any nightmare or it eased it. This is is the first time in my life I'm not afraid to go to sleep because of the nightmares. It works better than I expected. I see there's some people on here that are on a higher dose than 1 mg but 1 mg works great for me!

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I never got hung over from it - it doesn't actually make you sleepy per se - at least, it doesn't make me sleepy.  I don't find it to be a sleeping pill that way.  It just takes away the hypervigilance and I don't have nightmares when I do sleep.

 

Just you might be a bit dizzy if you stand up too fast, especially the first couple times you take it.

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I never got hung over from it - it doesn't actually make you sleepy per se - at least, it doesn't make me sleepy.  I don't find it to be a sleeping pill that way.  It just takes away the hypervigilance and I don't have nightmares when I do sleep.

 

Just you might be a bit dizzy if you stand up too fast, especially the first couple times you take it.

 

Thanks for the input.  I'm definitely not dizzy.  I feel like my blood pressure has shot up though, and got a massive wave of nausea that I needed Zofran for.  After the diarrhea ends I'm going to try and sleep. 

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Thanks sonic.  At the moment it is starting to work, not all the way, but I don't remember much when I wake up.  The things I remember are from dreams that were so intense and repetitive in the dream on the same topic, but if I distract myself for a bit after waking up, the memories pretty much go away.

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Idk.  As it is now I am on 17+ medications, so adding one that helps with side effects for another new one isn't really appealing.  Also, the migraines aren't receptive to many meds (if any).  I use a muscle relaxer, excedrin, and ice packs, which all seem to work as things that help.  It is the frequency that concerns me,

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  • 2 weeks later...

 

Patients with post-traumatic stress disorder (PTSD) are frequently symptomatic despite being on medications currently approved by the US Food and Drug Administration for PTSD. There is evidence to support the notion that prazosin is effective for PTSD nightmares. However, PTSD-related nightmares often do not resolve completely on a low dose of prazosin. The capacity of prazosin to treat daytime symptoms of PTSD which are distressing to patients has not been well studied. Clinicians are reluctant to increase the dose of prazosin due to side effect concerns. To date, the highest reported dose of prazosin used for PTSD is 16 mg daily. We illustrate two case reports using high-dose (up to 30 and 45 mg) prazosin for PTSD with comorbid treatment-resistant mood disorders. We report that high-dose prazosin was safe, tolerable and effective for PTSD in adults. To our knowledge, this is the first case series to highlight the importance of using high-dose prazosin for the treatment of PTSD. In patients with partial response to currently available medications for PTSD, greater utilization of high-dose prazosin for the management of PTSD may lead to better outcomes.

 

 

 

This is a link from a study.....I think 2 mg just ain't enough.

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Subjects were more improved when they were taking prazosin than when they were taking placebo on the primary outcome measures of nightmares, sleep disturbance, and global change in PTSD severity and functional status (t1). Moreover, prazosin was more effective for reexperiencing/intrusion, numbing/avoidance, and hyperarousal symptom cluster scores as well as total scores on the Clinician-Administered PTSD Scale. Effect size analyses for dependent variables showed robust and clinically meaningful reductions in symptoms across all outcomes measured (10).

Prazosin was very well tolerated. Two patients experienced mild orthostatic systolic blood pressure decreases (10 to 20 mm Hg) and dizziness early during prazosin titration, which resolved as the dose was increased. At prazosin endpoint, mean systolic blood pressure was 135 mm Hg (SD=12) supine and 129 mm Hg (SD=12) standing; diastolic was 89 mm Hg (SD=8) supine and 84 mm Hg (SD=15) standing.

All patients completed all conditions except for those in the second placebo condition. Five patients experienced a rapid return of distressing nightmares during postprazosin washout. Four experienced no benefit from their second placebo treatment and insisted on discontinuing the study so they could be given open-label prazosin; these patients rapidly improved after receiving the active drug. Last observation carried forward analysis was selected to impute conservative endpoint 2 values for these subjects. Empirically, the change scores for these early termination patients were very similar to those for the five first-period placebo subjects.

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  • 1 month later...

Anyone here have good results with this amount? I discussed with my doc to at least consider I have PTSD and he is........I have bumped up twice due to nightmares returning but hoping someone here has good results with this mg.

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Well. I've never tried it. So Idunno.

I just want to remind you that not everyone is reading the boards all the time, so sometimes it can take a little while get a response. I know that it's hard to have patience.

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You have four prazosin threads.  I counted.

 

People have replied to you about their doses and experiences in every single one.

 

And it takes people time to get around to the boards.

 

Can you seriously just calm down?

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Hey Sonic. 

I want you to know that I merged all your threads. They're all about the same thing. Dosing levels are really individual. If you aren't finding relief at a certain dose then maybe it's time to go back to your doc - you are working with your doc, right? - and talk about either upping it or trying something else.

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Yes of coarse.....I must have little faith in people....Since we are all human it just makes me think that there going to just stay.....At least medication gives me hope thru ppl's testimonies but even that ain't enough anymore. I'll look into therapy but right now just trying to raise it and get the same effect most people do at higher doses to take there nightmares away.

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Sonic, I just want to encourage you to work with your doctor. It never goes well when you mess with your meds on your own. If this med doesn't work out, I'm sure there are others your doctor could try. Stay strong and don't give up!

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Knock on wood. Not one single nightmare last night.......I mean the type of sleep i have yearned for so long I got last night......And I don't mean the type where I just got lucky and didn't have a terrible dream....My body feels refreshed, my heart pressure is low.....And I feel calmer.

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I'm starting to sleep walk.....And the seroquel gives me a eerie feeling right before bed........It's a strange like I took a psychadelic type feeling.........I think the seroquels going to have to be replaced with something else,

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I would tell your pdoc about the sleep walking and maybe ask for a med tweak or change, like you said.  Sleep walking scares the crap out of me, and I worry that I might do something I regret or that is dangerous and not know it.  I wouldn't want that to happen to you.

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