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Neurontin (gabapentin) dosing


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I posted in migraines regarding gabapentin usage prn for migraines but know have a dosing question and figured this was the best place to ask.

I new neuro (a great guy!) gave me a script for gabepentin to be used prn for migraines.  When I get the aura, I am supposed to take 300mg-600mg and 1-2 painkillers (at the moment percocet but will changed to roxicodone shortly).  If this does not make me sleepy I can take more every 2 hours or so.  The med should 'knock me out' and allow something (I don't remember the name) in the brain lining that is aggravated during a migraine to fall a sleep, therefore relieving the migraine when you wake up.  So far I have taken up to 2100mg - 3200mg with no sleepiness at all.

I was wondering for those that have taken/are taking gabepentin or Neurotin, at what dosage does this make you sleepy/knocks you out?  Are you taking brand name Neurotin (pill or liquid) or generic gabepentin?

Thanks!

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i'm sorry, firedancer - i haven't been on neurontin personally, and until your question i'd never heard previously of neurontin being used PRN. it seems somehow counterintuitive, since that isn't how ACs tend to work. drowsiness, though, is definitely going to be a YMMV thing, and depend upon your personal chemistry. meds which list drowsiness as a side effect don't make everyone who takes them drowsy. i'd think it would be hard to differentiate between drowsiness caused by the roxicet and drowsiness caused by the neurontin, though?

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Firedancer: I used to take neurontin for sleep and to prevent icepick headaches. I eventually worked my way up to 4800 mg. I stopped taking it because I got tired of gaining weight and having fat ankles. I started taking Topamax instead---which didn't work at first, but now is working very well (along with Wellbutrin). I also should add that I stopped neurontin cold turkey---a BIG mistake!

Vicodin or tramadol and valium (or other benzo) work pretty well to get me to sleep off a bad headache. Fortunately, I have not had to do that since June.

DBea

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Unfortunately, I took Topamax for 6 months and it never helped with my migraines.

Can't wait to see what he prescribes next.  I feel like I am running out of options.  The only thing that I know knocks me out is a combo of halcion and demoral because that is what I take when I have dental work done for sedation dentistry (I have a HUGE fear of dentist).  This knocks me out for hours.  But I doubt he will prescribe that.

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Sorry, firedancer.

I have been trying to find something on the use of gabapentin as an abortive treatment for migraines.

I really haven't been able to find anything.

But it is good for neuropathic pain which is often a partial cause for migraines.

It is possible that it could make a difference when used prn, though you said you were also taking pain killers with it.  As far as I know it is most effective when taken as a preventative, consistantly.

I'm not sure if you had already tried taking it as a preventative or not, but that may help.

I'm sorry you are having such a hard time finding something for the migraine.  I really can't recommend anything right now, except maybe check out the migraine board.

~navy~

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Hi:

  I answered on your other thread. I think I said it knocked me out at a very low dose. I get knocked around by ANYTHING at a low dose.

  We are all different. I have never heard of neurontin used prn either. Soooooo - experiement. It is a safe drug. Maybe take some on a night you don't have a headache and see how much it takes. Usually people start with 300 mgs.

Breeze

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Thanks you guys.  I wasn't too sure about it being a preventative either, but the neuro is a migraine specialist, so I figure he knows what he is talking about.

The nurse finally called me back on Friday and called in a script for Lyrica, which is so new I can't find anything on it.  All that I have found is that is supposedly the new Neurontin (generics and all come in to play). I am to take 50mg for a week and up to 100mg - to be taken at night. 

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Here is a link to an abstract on the use of gabapentin for idiopathic stabbing headache (icepick headaches). I'll try to post a link to the whole article (you need a subscription). I have read the entire article and the jist of it is that it works for acute icepick HA pain, but I don't think they studied migraine---although the 2 are related---I get both types of HA pain.

http://www.ncbi.nlm.nih.gov/entrez/query.f...2364&query_hl=4

Re: neurontin dosage---I remember my neurologist telling me that sometimes he takes 300 mg to sleep and he feels hung over the next day!! 300 mg barely touches me. I think I need a personal anesthesiologist to knock me out when needed.

diane

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Hi, Firedancer

Sorry to hear you are having such problems trying to sleep.  My experience with the Neurontin is kinda the same.  It does not make me sleepy but it does help with the sleep when I actually get there.  I take mine for the nerve pain (muscle spasms) and my current dosage is 300mg 3x day but I usually end up taking more than that.  Have you tried taking Ambien or Lunesta for sleep?  Best of luck to you.......

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