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Tolerance to Mirtazapine & Doxepin


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I can only speak about Mirtazapine. Mirtazapine is not really a sleep med although it sometimes is prescribed as such. The thing is that the sedation from Mirtazapine tends to go away as you become used to the med. This is what we tell people who are afraid of taking it as an antidepressant because of the sedation, and it is true. The sedation does lessen with time.

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