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Hi,

Has anyone taking antidepressants ever been thrown into a bad depressive episode while taking an antibiotic? I have been taking Paxil for a while and recently got the flu with it turning into a sinus infection. I was prescribed Levofloxacin for the infection but since taking it I have been getting worse mentally and emotionally. I am in a full blown depressive episode and am looking for some hope that this is because of the antibiotic. I took 5 daily pills of a 10 day dose for the Levofloxacin and decided to stop after todays dose.  Please let me know if you have experienced this.

 

Thanks,

Looking for some hope.

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Has anyone taking antidepressants ever been thrown into a bad depressive episode while taking an antibiotic?

 

No, I have not.  But personally though, I won't take meds related to Cipro (Levofloxacin is in the same class as cipro) because of side effects.  I realize everyone is different, but after taking cipro and reading about it, this class of meds make me nervous to take them.  I also can't take Keflex because it effects my kidneys.

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Please don't stop your antibiotic. 

 

I don't know if it is interfering with your MI meds or not. That would be a really good question to ask your pharmacist. You can call your pharmacy now and ask to speak to a pharmacist. That is literally their job - to know and talk to you about how medications interact with each other, and also to help you with communicating or fixing those issues with your doctor.

 

But really. Stopping midway through a course of antibiotics is how we create antibiotic resistant bugs which are another health care crisis problem. Please contact your doctor or pharmacist before stopping or changing ANY medication.

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I wouldn't advise stopping your antibiotic since you have just a few days left to take it. It could be making you more depressed, but your physical health is important too so I'd follow my doctor's advice if I were you.

 

I'm going to move this to our antidepressants board. The interaction between antidepressants and antibiotics is an interesting question.

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I had a very weird reaction to avelox, another fluoroquinolone. Got weepier over 3 days of taking it, then woke up with the bedroom rapidly rotating...like when you're drunk, but imagine it waaaaay faster?

Had to call off work, go to cipro. Cipro was fine.

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I had a very weird reaction to avelox, another fluoroquinolone. Got weepier over 3 days of taking it, then woke up with the bedroom rapidly rotating...like when you're drunk, but imagine it waaaaay faster?

Had to call off work, go to cipro. Cipro was fine.

 

Good point. Whitney1 go back to your doctor and tell him/her that the antibiotic is making you more depressed. They might be able to switch you to something else that doesn't make you depressed. But please don't just stop taking your antibiotic.

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I let my GP know that I came off the antibiotic and he was okay with it. Talking to my Psyhciatrist, she believes my current episode was caused because 3 or so months ago I weaned myself off of Welbutrin for some odd reason and she mentioned that a condition arises 3 months  coming off Welbutrin were you either remain fine or you crash. I seemed to have crashed and now am stating back up on Welbutrin along with uping my Paxil slightly. Anyone ever run into this situation? If so how long did it take for you to feel better?

 

Thanks.

Edited by Whitney1
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