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Help! Quetiapine, Risperidone, Olanzapine, Temazepam, Trazodone


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Pulled an all nighter and really want to go to sleep tonight.

Please let me know if any of you tried any of these.

 

(1) Quetiapine: Currently on this seroquel for sleep and went upto 250. Has anyone gone up higher than this and get knocked out? Even with seroquel being more sedating at lower dose, etc

 

(2) Risperidone: I know this is not usually used for sleep but anyone get knocked out with this?

 

(3) Olanzapine: I've tried it before but is it good for sleep mid/long-term?

 

(4) Temazepam: Does this build up tolerance quickly?

 

(5) Trazodone: Does this build up tolerance quickly and even work?

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I've used quetiapine, but not currently past 50 mg. I don't know about it at higher dosages.

 

Risperidone puts me to sleep quite well. I went off it because I was having nasty hangovers in the morning, but it definitely knocked me out.

 

I've used olanzapine as well, but strangely it wasn't sedating for me (this is really unusual though).

 

Trazodone did really weird things to me once (blood pressure dropped really low and I had an anxiety attack in the morning), so I haven't touched the stuff since that one time.

 

That said, do you have access to all of these? How's that possible? I'd be wary of self-medicating and would stick with what's prescribed.

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Funny of my relationship with my pdoc.

 

I "recommend" (direct/tell) him what to prescribe. 

Because he has no idea what works.

 

I also have urgent care docs both nearby and on-call pdoc from my clinic who can prescribe emergency 1-2 days worth of tablets.

 

lol, I can act like a pdoc at this point.

 

I've used quetiapine, but not currently past 50 mg. I don't know about it at higher dosages.

 

Risperidone puts me to sleep quite well. I went off it because I was having nasty hangovers in the morning, but it definitely knocked me out.

 

I've used olanzapine as well, but strangely it wasn't sedating for me (this is really unusual though).

 

Trazodone did really weird things to me once (blood pressure dropped really low and I had an anxiety attack in the morning), so I haven't touched the stuff since that one time.

 

That said, do you have access to all of these? How's that possible? I'd be wary of self-medicating and would stick with what's prescribed.

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So, basically you have a bad relationship with your pdoc and do a bit of doctor shopping on the side to pick up short doses of meds when you want to.  Doesn't sound like a recipe for success.  What are your options for finding a doctor with whom you can actually build a longterm relationship?

 

eta It's most common for people to find quetiapine sedating at lower doses. I'm not one of them, and you may not be either, but I don't want to encourage you to self medicate by raising the dose on your own, even though (trust me on this) I know the desperation of not being able to sleep.

Edited by MiaB
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Doctor shopping is probably the right word. My last one lasted a year and a half and she was starting to recommend sleep therapy(which hasn't worked before several times in the past), so I switched to someone who is more liberal 4 months ago. With my sleep problem at this point, I don't think long-term relationship would be that helpful as much as finding someone who will give me stuffs so I can sleep. Last time I had a 3 year relationship with a pdoc and he moved out of the area. So ever since, it's been a doctor shopping. But then I might be wrong, you're right, I should be really be going to a doc who eventually wants to get me off of the sleep meds. It's mostly my reliance on meds that's the core problem. I'm very stubborn and it's not good. I know this but I can't help it.

 

Also, not many psychiatrists around 2 hours north of Chicago.

Yea the sleep desperation, I can understand the desperation Elvis Pres and Michael Jackson went through as to why they did what they did. 

 

So, basically you have a bad relationship with your pdoc and do a bit of doctor shopping on the side to pick up short doses of meds when you want to.  Doesn't sound like a recipe for success.  What are your options for finding a doctor with whom you can actually build a longterm relationship?

 

eta It's most common for people to find quetiapine sedating at lower doses. I'm not one of them, and you may not be either, but I don't want to encourage you to self medicate by raising the dose on your own, even though (trust me on this) I know the desperation of not being able to sleep.

Edited by snd
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Doctor shopping does not mean simply shopping around for a doctor, it's a term that's used to describe a certain type of drug seeking behavior, where you will go to multiple doctors to get prescriptions for controlled drugs. 

 

You need to pick one doctor and stick with them.

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I've never done any illegal drugs or take meds not prescribed to me for any recreational purposes, etc.

But you are right in that for sleep, I'll do anything(except illegal activities). It's been a while since I slept naturally on my own strength.

 

I'll stick with the current one. 

Thanks for the advice.

 

 

Doctor shopping does not mean simply shopping around for a doctor, it's a term that's used to describe a certain type of drug seeking behavior, where you will go to multiple doctors to get prescriptions for controlled drugs. 

 

You need to pick one doctor and stick with them.

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I don't know you, so can't make a judgement on whether or not you should be on meds. I do think it's simplifying things to imply that it boils down to willpower.  Lack of sleep can have serious consequences on one's functioning (again, I speak from experience), but the best way you're going to resolve this is to stick with one person and work with him/her.  I know it can be hard - I've just been through the process of seeking a second opinion myself.  But "acting like a pdoc" and messing around with heavy duty meds on your own is only going to create more problems for you in the future as well as the present.

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Yep, it already did create problems. I haven't slept on my own strength in a long time. 

 

Thanks for the advice.

 

 

I don't know you, so can't make a judgement on whether or not you should be on meds. I do think it's simplifying things to imply that it boils down to willpower.  Lack of sleep can have serious consequences on one's functioning (again, I speak from experience), but the best way you're going to resolve this is to stick with one person and work with him/her.  I know it can be hard - I've just been through the process of seeking a second opinion myself.  But "acting like a pdoc" and messing around with heavy duty meds on your own is only going to create more problems for you in the future as well as the present.

Edited by snd
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North West of Chicago is more accurate description.

But still, maybe I'm too lazy. (But not lazy to shop for docs for meds? what a hypocrite)

 

 

Two hours north of Chicago? Are you in Michigan? Because if you're not, you should be in proximity to either Milwaukee or Madison, WI, both of which are crawling with doctors.

Edited by snd
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  • 4 weeks later...

I went up to 600mg quetiapine and it's always been brilliant for sleep. I find melatonin and quetiapine works amazingly. My doctor basically said that the melatonin gets you to sleep, and the quetiapine keeps you asleep. Melatonin has been massively helpful for my insomnia, and sometimes if I forget to take my meds I still get enough sleep to last me the day without collapsing. That's never happened before taking it.

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Often with melatonin, people find that "less is more". That is to say, many people find that taking more melatonin makes it more difficult to sleep than when they take smaller doses.

 

 

 

Mistake #6: The dosage amount isn’t important.

The problem with melatonin is that it was discovered long before scientists really understood what it does and how much you need. For example, in the late 80’s and early 90’s, we thought melatonin was a sleep hormone. Now we know it is much more complicated. In addition, tablet sizes average 3-5 mg. New evidence shows that adult males only need 150 micrograms, and the average female needs only 100 micrograms (a microgram is 1/100 th of a milligram). So the average melatonin supplement is 20 – 50 times more than we need! If you are using regular melatonin tablets, you can cut the pill into fourths, otherwise, try to find the smallest pill size available. If you are taking time-released melatonin, do not break the pill, as this will ruin the time-release.

- See more at: http://www.talkaboutsleep.com/how-to-use-melatonin-correctly/#sthash.tr8IVrHh.dpuf
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  • 1 month later...

Pulled an all nighter and really want to go to sleep tonight.

Please let me know if any of you tried any of these.

 

(1) Quetiapine: Currently on this seroquel for sleep and went upto 250. Has anyone gone up higher than this and get knocked out? Even with seroquel being more sedating at lower dose, etc

 

(2) Risperidone: I know this is not usually used for sleep but anyone get knocked out with this?

 

(3) Olanzapine: I've tried it before but is it good for sleep mid/long-term?

 

(4) Temazepam: Does this build up tolerance quickly?

 

(5) Trazodone: Does this build up tolerance quickly and even work?

Currently on Seroquel XR for sleep and Bipolar 1. I got up to 200mgs of regular Seroquel and it was knocking me out for 12 hours a night so I was switched to Seroquel XR because it doesn't pack quite that big of punch, and it last longer for the bipolar issues. I was also on 150 mgs of trazadone, and that put me down like a tranquilizer. I mean I did not wake up at all from the time I close my eyes at night until I opened the in the morning, I was dead asleep. My tolerance did not build up quickly, it took me a couple months to go up from 50 mgs to 150mgs. I had to ween off it because it started giving me migraines(which I am already prone to). I hope this is in anyway helpful to you!

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  • 2 months later...

I am on Zyprexa and Temazapam currently as well as Armodifinil. The Zyprexa caused me to gain a lot of weight but the other Atypical anti-psychotics had side effects. I was also on Ambien and lunestra but ended up sleep driving. The Armodifinil is new and I kind of feel angry a lot when I take it. the temazapam helps a little but my main issue is the armodifinil. I don't know it it needs to build up in my blood in order to get over the side effects but I only take it 5 days a week. I was on provigil but built up a tolerance. I feel angry or irritated on armodifinil but not provigil

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Sympathize with the sleep issues; I've had various problems for years.

Severe sleep apnea which required a BiPAP...lost a lot of weight and that's mostly, but not quite under control.

Did ambien for several years. That was actually quite reliable, but both I and my doctor wanted me off due to potential risks of long term use.

Was on ziprasidone for depression for about nine months, which resulted in not getting much more than 3 hours of sleep at a time. That just about killed me. Literally. Had a complete breakdown and was off work for a week and switched to quetiapine and cymbalta for depression and temazepam for sleep. I've since quit all three...the quetiapine was extremely sedating. For some perverse reason, my psychiatrist responded to the complaint of being sedated by giving me an increase in dose and a switch to an extended release version. I took one dose and could barely stay awake for about 24 hours. Caused a significant deterioration in our relationship. Went back to the regular dose, then quit both it and the cymbalta after about 4-5 months -- did nothing for the depression and caused around a 25 pound weight gain.

I was able to cut back on the temazepam -- which worked relatively well for sleep -- by cutting the dose from 30 mg to 15, then quitting. Trying to get off benzodiazepines in general -- dependency issues. Still working on the clonazepam.

For sleep, I ended up with something called somnapure. It's mostly melatonin with some other natural herbs and the like. I take a couple of those, and usually a benadryl or two (I have lots of allergy problems, so I get some relief in addition to it being sedating). That generally will get me up to about 5-6 hours of sleep.

I think ultimately meds aren't really a solution -- you will generally sleep, but quality is poor and you won't cycle properly through different stages. You need to retrain yourself. My psychiatrist had some very limited suggestions, not especially helpful. Sleep specialist thinks that as long as I use the BiPAP (which is uncomfortable and I think I've reached a point of diminishing returns) everything will be awesome.

So I sort of feel like I'm on my own.

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  • 3 weeks later...

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