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Effex ore XR worked the second time

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ok, I remember trying Effexor a couple years ago. I mainly stayed on 75 mg. when the doc lowered it three months ago I started to get depressed even tho I really didn't think Effexor was doing much. So after going from 37.5 to 75 my depression lifted and it wasn't placebo either. So has anyone here been on a antidepressant that didn't work the first time but worked the second time?

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