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Anyone here take Prazosin and Gabapentin?


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After upping Latuda to 40mg my anxiety skyrocketed.   The dr lowered it back down to 20 but I'm scared to take it now.  Two hours after I take it, the anxiety and restlessness start up.  I also take Cogentin and lorazapam at the same time, but it doesn't help.

I just started Prazosin for nightmares/ptsd and also asked for Gabapentin.  Dr. didn't want to do to many changes at once, so I didn't get it.

Anyone take both Prazosin and Gaba?  Have you found this combo helpful?

Thanks in advance!

Edited by Fluffypinkbunny
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I have taken both at the same time in the past.  The prazosin has always worked well for my nightmares starting from the first time I took it, five or so years ago.  I have also asked for prazosin when a triggering event causes my nightmares to flare up, but I don't like taking it long term because I can feel kinda groggy when taking it.

However, I didn't notice any lessening of my anxiety or restlessness with the gabapentin and I'm on a fairly high dose for fibromyalgia.

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Thank you!  I didn't get the gabapentin but am staying on the Prazosin.  It does help with my nightmares but now I'm feeling dizzy in the morning.

Update: I'm really liking the Prazosin.  The dizziness has subsided and it's helping with the nighmares.  I also feel very calm during the day.  It's a keeper in my cocktail.

Edited by Fluffypinkbunny
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