Any experiences with desipramine?

[enduranceessential]

Thinking of asking pdoc if we can add it to my cocktail for bipolar depression...

[Rabbit37]

Well, how I reacted to it may be totally different for you. It was prescribed for depression, this was before I was accurately dx'd as BP, so i was taking it without a mood stabilizer. Pretty much from the first dose, I couldn't sleep, mind racing, yep, a step into hypo/mania. What I really remember is about 3 or 4 days into it, it must have really kicked in, there was a sudden sensation of ice water being poured from my scalp to my spine. Sorry, not trying to be a drama queen, I've been through my fair share of meds, this was the wildest. Stopped it a couple of days after. 

I hope that doesn't scare you away, it's certainly worth a try, anyway. 

Edited November 4, 2015 by Rabbit37

[MiaB]

I'm moving this to the antidepressant board, where more people are likely to see it.

Mia (mod)

Edited November 5, 2015 by MiaB

[melissaw72]

I was prescribed it for OCD awhile back.  It didn't help much, and AFAIK I remember didn't have any side effects.  I wasn't on it for very long, but I did give it about 2 months to see if it did help.

Was prescribed anafranil after that, which helped a lot better.

Edited November 5, 2015 by melissaw72

[enduranceessential]

Thanks for the insights. According to my genetic testing with pdoc it is in the "good" column for me, so I hope we'll give it a shot. He seems somewhat biased against the tricyclics, but I've had next to no success with SSRIs and the other classes. I will provide an update.

[malachite]

Tricyclics have been far more effective for me than ssris. I was on desipramine years ago, but had to discontinue due to trouble swallowing. I hope it helps you.