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Rabidtears

Why does missing meds make you manic?

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I apologize if this has already been posted..

I'm newly diagnosed as bipolar 1. I took risperdal 2mg for about 5 months along with zoloft 100mg. I tried not to miss it because I tended to get even cranking than I was when I did take it. Then I started taking Risperdal 3mg but I was still a grouchy old hag half the time, but was gaining a lot of weight...that's besides the point.

 

I now take abilify 5mg and topamax 50mg twice a day. Friday night I fell asleep early and accidentally forgot to take my medicine. It was totally unintentional. I woke up the next day in the very very best of moods. I had sooo much energy. I was so happy I got on my own nerves? Could have randomly burst into song days? I explained to my husband that it felt good but it was a scary and terrible thing because that state is so unpredictable. I did end up doing and saying some very regrettable things that night that warranted a trip to the hospital but I refused. 

Anyways, long story short, I switched from one antipsychotic to another. Why does missing one make me super mean altogether and the latter one make me start offeuphoric until set off by any triggers? Then I became violent/hostile with SI.

I was mouthy on risperdal, but with this new combo I destroyed my kitchen! With a broomstick! And the things coming out of my mouth have been even worse :/

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I don't know anything about topamax, but I'm on abilify. My pdoc explained it takes a long time to build up a good level, or get down to a lower level, when you change doses. So I wonder if you have actually reached a good, steady level of abilify yet, or if it's missing the topamax that caused the changes?  Either way, it sounds a pretty fragile balance just now. Personally, I had to change when I took my nighttime meds to tie them to a different thing, so I'd for sure take them. (for me, it's when I feed the dogs, since I do that at a set time without fail). I know some meds have a shorter half-life and are more critical to need to not miss doses. At least now you know you can't afford to miss a dose, I hope things even out a bit more for you, though. 

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Thanks sugar, I've made sure to take them as ordered since then, and I did last night and this morning, but today I am euphoric! Just like I was Friday when I missed it. I am praying that it holds through though and that I don't snap again. It's a scary feeling yet wonderful.

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Have you been on Abilify very long? When I took it, and I didn't stay on it long, I found it very activating. It made me feel as if I was crawling out of my skin, actually. A lot of people find it activating at first.

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7 minutes ago, Gearhead said:

Have you been on Abilify very long? When I took it, and I didn't stay on it long, I found it very activating. It made me feel as if I was crawling out of my skin, actually. A lot of people find it activating at first.

Watch out. Abilify made me manic. I didn't sleep for a week and was hypersexual and went on a spending spree until I ended up in the hospital. I would check in with your pdoc just in case.

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I have SZA bipolar type. I take 30 mg of abilify daily. I don't know what your therapeutic dose will be, but give it some time to work (unless you are having life threatening side effects, of course). And 5 mg is a dose used for an add on for depression mostly. Best to ask your pdoc why you are taking a low dose.

And FWIW, lots of meds make/made me manic but abilify has never been one of them. I had to give it time to work, and I was restless at first, but it really has been a game changer for me. Of course I am also taking seroquel xr at 800 mg. Which is better at stopping mania IME but still I wanted to let you know not everyone gets manic from abilify. There is a new warning on it though for compulsive behaviors like shopping way too much or gambling too much. My pdoc just told me this and asked if I wanted to switch meds because of this. I don't think I have this problem but it's something to keep an eye on.

Anyway, call your pdoc as soon as you can regarding your dose and your euphoria. It may or may not be the abilify. Only your pdoc can judge that. Good luck and I hope it starts to work better for you!

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7 hours ago, Wonderful.Cheese said:

I have SZA bipolar type. I take 30 mg of abilify daily. I don't know what your therapeutic dose will be, but give it some time to work (unless you are having life threatening side effects, of course). And 5 mg is a dose used for an add on for depression mostly. Best to ask your pdoc why you are taking a low dose.

And FWIW, lots of meds make/made me manic but abilify has never been one of them. I had to give it time to work, and I was restless at first, but it really has been a game changer for me. Of course I am also taking seroquel xr at 800 mg. Which is better at stopping mania IME but still I wanted to let you know not everyone gets manic from abilify. There is a new warning on it though for compulsive behaviors like shopping way too much or gambling too much. My pdoc just told me this and asked if I wanted to switch meds because of this. I don't think I have this problem but it's something to keep an eye on.

Anyway, call your pdoc as soon as you can regarding your dose and your euphoria. It may or may not be the abilify. Only your pdoc can judge that. Good luck and I hope it starts to work better for you!

Thank you Cheese, it has definitely been a roller coaster for me as well as for my family. I've been journaling and charting every day. It can be tough to not get discouraged. My support system is strong though. So far, so good. Ish. I am loving this group. =)

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9 hours ago, Wonderful.Cheese said:

I have SZA bipolar type. I take 30 mg of abilify daily. I don't know what your therapeutic dose will be, but give it some time to work (unless you are having life threatening side effects, of course). And 5 mg is a dose used for an add on for depression mostly. Best to ask your pdoc why you are taking a low dose.

And FWIW, lots of meds make/made me manic but abilify has never been one of them. I had to give it time to work, and I was restless at first, but it really has been a game changer for me. Of course I am also taking seroquel xr at 800 mg. Which is better at stopping mania IME but still I wanted to let you know not everyone gets manic from abilify. There is a new warning on it though for compulsive behaviors like shopping way too much or gambling too much. My pdoc just told me this and asked if I wanted to switch meds because of this. I don't think I have this problem but it's something to keep an eye on.

Anyway, call your pdoc as soon as you can regarding your dose and your euphoria. It may or may not be the abilify. Only your pdoc can judge that. Good luck and I hope it starts to work better for you!

Definitely give it time to work.  It can take 6-8 weeks for it to get into your system.

Abilify never made me manic either.  If anything it made me tired.  It worked for me at the 7 week mark, and I started out slowly with it, from 5 mg to my current dose of 30 mg. 

And definitely call your pdoc about it.  Like Cheese said, it may or may not be the abilify.

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It only takes 14 days for Abilify to reach a steady state.  So, like most AAP's, it really shouldn't take 6-8 weeks to kick in, once you're at a therapeutic dosage.

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For me anyway, it took a lot longer to reach a therapeutic dose than 14 days.  Took me 6-8 weeks (it was actually the 7th week).  I reached therapeutic levels at 6-8 weeks, but then I needed to increase the med and came to another therapeutic level, etc until I got to 30 mg (was 45 mg; had to go down).

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