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Can you compare SSRIs to TCAs?

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I wouldn't base my med decisions on receptor binding profiles. The best source of information is your pdoc who has experience with these meds and has seen numerous patients on TCAs and who has also read the studies.

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I have to agree. I'd have to refer to my professional knowledge on what I should try. Psychiatrists are the ones who have studied to death these types of medicines, they're the ones to turn to for information about what's best suited for you. It is still somewhat of a guessing game at best about what will work for you but they're the best springboard here.

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