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Zyprexa helped me immensely.  It felt like my brain woke up, now 6 months later I am experiencing tightness in my legs at night plus insomnia, all new symptoms.

Currently on 5 mg Zyprexa. 

Last night took 1/2 of a 25 mg Seroquel and 0.5 mg of Cogentin at 3:30AM and was able to sleep.

I am trying to stay away from Seroquel as it causes daytime sedation, plus I am gaining weight like crazy.

Talked to my psych doc today and he encouraged me to try 1/2 of the Zyprexa tablet during the day and 1/2 at dinner time with the cogentin and seroquel, giving all

three time to clear my system by the time I wake up.  I have a very slow metabolism. Right now experiencing dizziness and more sedation as the afternoon progresses.

I feel I am out of options.  Zyprexa is the only drug that helps with all my symptoms.

Thank you for listening.  Any helpful suggestions would be appreciated.



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I always had some daytime sedation from seroquel, even if I took it at 8 pm. It was bad enough I could sleep through two alarms the next morning. There are other options for insomnia, thankfully. Have you tried any of the Z drugs?

At least you're stable on the zyprexa, that's awesome.

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Hi dtac ~  Thank you for your reply :) What are the Z drugs?  

Yes, daytime sleepiness I have always had with Seroquel and I take it at 6PM. 

I took 1/2 of a 5 mg tablet of Zyprexa at noon today and it's already 4:15PM.  Feeling some sedation and trouble with walking but otherwise I feel as if the Zyprexa woke up my brain. I can feel it fighting the inking in of depression or the bounce of a mood the drug is fighting off. 

Just spoke with my psych doc and I am going to move all my psych meds to later on in the day and evening so I can function and hopefully sleep thru the night.  Battling sleep at 3:30AM is no fun, same with the leg jerks and cramps.


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Hi Andy ~  Oh yes, got it, thank you.  Have tried Amien, Lunesta, Melatonin, etc but they all stay with me thru the following day. Even Benedryl does that to me too. Then I'm up at night eating and don't remember it, LOL.

But, I will keep that ace up my sleeve if my sleep doesn't improve. 

BTW, where can I go, on this site, to put the drugs I am on, dx's etc,like you have ?


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