Jump to content
CrazyBoards.org

Recommended Posts

I had a psychotic episode in september and have been on risperidone since. Since my prolactin levels were getting too high, I'm now switching to abilify. I'm afraid that the risperidone has made me anhedonic. My psychiatrist is tapering the risperidone down and increasing my abilify. Is there anyone out there who has recovered from this anhedonia after they came off the risperidone and if so how long did it take? 

Edited by marvinoman

Share this post


Link to post
Share on other sites

Risperdal didn't give me anhedonia, but anhedonia is a major part of my depression. Abilify helped immensely with my anhedonia.

Share this post


Link to post
Share on other sites

after i have an acute psychotic episode i always go through this post psychosis depression thing. there are studies that show it happens to many of us. when the meds start getting rid of the voices and the thought control and other activities and ideas you may have, you suddenly realize you haven't kept up with anything else in your life. it's demoralizing. and then fixing it is seems overwhelming. i had a lot of help to keep my life semi in order and i still do. itt's really hard. but i don't know that the meds ever gave me anhedonia so much as after they knocked out my much bigger and more challenging "positive" symptoms...the negative ones remained. and the disorganized ones, too. 

you might see if it's possibly the post psychosis depression that is essentially a foray through negative symptoms. it happens to me after my head shatters from the disorganized symptoms. then i just can't be bothered to do or give a shit about anything except maybe cigarettes. 

i hope you've had a chance to talk to your prescribing physician. how'd it go? did he agree that the anhedonia is from risperdal?

 

  • Like 2

Share this post


Link to post
Share on other sites

@mellifluous My psychiatrist told me it wasn't caused by the risperdal but was caused by depression. Though i was never really depressed or suicidal or anything like that. I just have the anhedonia. It may be the post-psychosis depression you were talking about but i never had negative thoughts. My psychiatrist just assigned me wellbutrin do you think that will help? 

Edited by marvinoman

Share this post


Link to post
Share on other sites

Newer antispychotics, AAP's (atypical) are pretty good at preventing negative symptoms like anhedonia, which is a big part of schizophrenia/psychosis, etc. It's extremely unlikely an AAP will cause anhedonia, people are extremely uninformed, and there isn't a peer reviewed study about an AAP causing anhedonia. Anhedonia can be a sign of depression. Coming down from something like psychosis, or mania (for example) isn't easy on the brain or body. Meds take a bit to kick in. 

@mellifluous has a very good reply.

 

Share this post


Link to post
Share on other sites
On 1/7/2017 at 8:04 AM, marvinoman said:

@mellifluous My psychiatrist told me it wasn't caused by the risperdal but was caused by depression. Though i was never really depressed or suicidal or anything like that. I just have the anhedonia. It may be the post-psychosis depression you were talking about but i never had negative thoughts. My psychiatrist just assigned me wellbutrin do you think that will help? 

hi marvin,

i don't have any experience with wellbutrin because it's an antidepressant and that's counterindicated for schizophrenia, which is my primary diagnosis. if your psychiatrist is prescribing it for anhedonia, then i think it's good to give it a shot  : )

i hope it helps and you're feeling (better) soon,

xx melli

Share this post


Link to post
Share on other sites

It seems simple to me, Risperidone may be an atypical antipsychotic, but it's one of the few (or only) ones that seems to antagonize EVERY single dopamine receptor. Man, anhedonia should be a freakin' primary outcome of taking that drug O_o 

I wouldn't voluntarily take an antipsychotic for any reason, heck, opiates have antipsychotic properties and I'm sure they're wayyy more fun. Sorry for hijacking the thread, I was just looking at Risperidone and knew that there had to be a ton of people who got anhedonia from it. I don't have amy psychotic illnesses. So, this will probably be my only post, cya.

Edited by Blinkyrocket
  • Like 1

Share this post


Link to post
Share on other sites

I hope it's your only post, since you don't know what you're talking about. Why would you drop in and critique a class of meds that you admit you would never try? You don't have an informed opinion, by definition. I'm guessing Scientologist.

Share this post


Link to post
Share on other sites
17 hours ago, Blinkyrocket said:

It seems simple to me, Risperidone may be an atypical antipsychotic, but it's one of the few (or only) ones that seems to antagonize EVERY single dopamine receptor. Man, anhedonia should be a freakin' primary outcome of taking that drug O_o 

I wouldn't voluntarily take an antipsychotic for any reason, heck, opiates have antipsychotic properties and I'm sure they're wayyy more fun. Sorry for hijacking the thread, I was just looking at Risperidone and knew that there had to be a ton of people who got anhedonia from it. I don't have amy psychotic illnesses. So, this will probably be my only post, cya.

Are you saying because it binds to all the Domaine receptors it causes anhedonia ? I don't see where this is established. AAP and AP have some antidepressant activity. Just look at the Serotonin receptors that they hit.

You will clear the Risperidone in five half-lives, lasting 20-30 hours each. 100 to 150 days,

  • Like 1

Share this post


Link to post
Share on other sites
17 hours ago, Blinkyrocket said:

It seems simple to me, Risperidone may be an atypical antipsychotic, but it's one of the few (or only) ones that seems to antagonize EVERY single dopamine receptor. Man, anhedonia should be a freakin' primary outcome of taking that drug O_o 

I wouldn't voluntarily take an antipsychotic for any reason, heck, opiates have antipsychotic properties and I'm sure they're wayyy more fun. Sorry for hijacking the thread, I was just looking at Risperidone and knew that there had to be a ton of people who got anhedonia from it. I don't have amy psychotic illnesses. So, this will probably be my only post, cya.

I took Risperdal FOR depression, and it did not make me anhedonic at all. In fact, it helped me. I wonder why you felt the need to comment on a medication that, by your own admission, you yourself did not, do not and will not ever have to take?

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Sign in to follow this  

  • Similar Content

    • By mikl_pls
      My mood has been absolutely deplorable for the past month or so. I honestly don't know how to begin to describe how bad it is. I have a lot of the "negative" symptoms, a profound deficit of positive affect. Nothing in life gives me pleasure, suicidal thoughts begin to surface, and I sometimes descend further into psychotic depression. These are my depressive episodes. I don't know how else to paint the picture more thoroughly because I never know what to say, and it really bothers me when I'm like that when I'm around my boyfriend. I want to talk, but I can never think of anything to say, so I rely on him to start conversations.
      I don't get it... Dopamine has been posited to be a central neurotransmitter in the pathenogenesis of anhedonia, and I'm on multiple meds that supposedly on their own and in combinations with other meds I'm taking can treat anhedonia. What am I missing??
      I'm on Dexedrine up to 60 mg as needed, Vyvanse 50 mg, Wellbutrin 200 mg, Viibryd 40 mg (increases dopamine via postsynaptic 5-HT1A receptor stimulation), Vraylar 3 mg... What else could possibly help?
      There's no relief in sight when I'm like this.
    • By Glatoss
      My brief period (6 months) on Sertraline has been that it sapped my creativity and basically made me not want to do anything, not feel anything. I just sit at the computer and watch videos and occasionally walk around, or eat, or go to the bathroom. I just don't have any drive to really do very much of anything, except what is needed for continued survival. I don’t even want to watch movies and series!
      Is that normal?
    • By maxor
      Hello Comrades,
      I've been taking Sertraline (50mg daily) for 9 months now.
      Reason for taking Sertraline: Depression & SAD. Maybe some GAD.
      So Sertraline treats my baseline anxiety quite well, also got rid of digestion problems, but I am struggling with side effects:
      Motor restlessness, agitation. I've always been quite "hyperactive", but Sertraline has worsened it by a good amount. I cannot sit still, I feel I have to walk, to pace. I move my fingers and toes to "release" some of the energy. Also lots of fidgeting, rocking back and forth. I have the urge to crawl out of my skin.
      _ Indifference, amotivation, apathy, lethargy. I get less things done on Sertraline than before Sertraline. Just want to sit around and do nothing. It is really disconcerting, because things would happen like a major car malfunction or someone f*ck*ng me over and I'd be thinking "this SHOULD piss me off, but, meh.. whatever.."! I've been doing some reading & research and there is the hypothesis that SSRI-induced-stimulation of 5HT2C & 5HT2A receptors dampens the dopaminergic transmission in the prefrontal cortex thus causing these specific SSRI side effects. Antagonism / Inverse Agonism of these receptors should theoretically resolve the problem. What medications do antagonize / inverse agonize these receptors? Are there any other reliable theories on what is causing this? And what could help?
      _ Sleep disturbances, f*ck*d up sleep cycle, crappy sleep. Falling asleep is difficult, shallow sleep, waking up a lot in the night => daytime fatigue. (This week I've been sleeping a lot, maybe because the body wants to compensate for last months's bad sleep?)
      _ Heat intolerance + hot flashes. My entire life I've been loving warmth and heat. I was the guy who could sit at the top row in the sauna for 20min @ 100°C (212 °F), but right now I cannot even stand a mild summer. And I have been getting hot flashes lasting between 10-15 mins several times a day (I am a 29 year old male, so pretty sure it is not menopause related)
      _ I also lost quite a bit of weight, partially due to loss of appetite, but also due to increased metabolic rate. My appetite is back to normal, but I am still not gaining any weight. BMI 20 right now.
      _ Palpitations (BUM BUM BUM BUM. BUM . . . BUM . . . BUM)
      _ mild headaches and "pressure" in my neck. Nothing bad, but very annoying in the mid and long term. Now I don't know what to do. I need some meds with "less" side effects. I haven't tried any combination of medications yet. To my dismay my doc prefers the SSRI merry go around aka SSRI carousel. I found a new psychiatrist and I will have a first appointment in about a month, but I don't know what to suggest to him. Has anybody some experience with a similar situation? Which antidepressant would be suitable for me? If there is someone who had the same problem and found some solution: please write me. Thank you. Greetings from Germany!
       
    • By lightriso
      Now several of my friends are aware of my self harm, and they have been giving me so much emotional support and surrounded me with positivity. I was texting one of them yesterday and I told her I was three days clean, and she said every three days I'm clean she would give me one of her gogos (they're cute toy things). I heavily insisted and said she really didn't have to, but she wanted to, she said she's doing it for me. I am so grateful I have such great friends to support me through this, thank you.
    • By lightriso
      I said in the previous post I was challenging myself to stay clean. It's pretty difficult. The first few days were pretty good, I had no urge to cut at all. But in the last twenty four hours I have been very close, I literally had the blade so close to my skin. But I said no, I can't do this, I have to be clean. But everytime I say that the urge grows. Right now, October 1st, I have been clean for eleven days.
×
×
  • Create New...