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Lamictal (lamotrigine) side effects


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Heya,

My (made-up, not in the DSM just yet) Intellectual Personality Disorder compels me.

There are *so many* threads about Lamictal and its side effects, not all of which are on the PI or monograph.

Seems to me that those of us on CB taking this weird and wild medication would wonder about a lot of them.

I *would* post a poll, but this free-form is better for now,and if it looks fairly consistent I'll think about a poll.

I'll start.

Sedation.

Acne.

Muscle pain.

Worsening rosacea.

Night sweats.

Breakthrough bleeding.

OK, now *you* go.

--ncc--

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Extreme muscle pain/tightness and horrendous headaches were the biggies for me, for about a month.

Breakthrough bleeding, again 1 month.

Continuing Qs re: hormonal interactions (I know, that's not a SE, but we wimmin folk sure seem to struggle with this).

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Restless feet when sitting.

At higher doses, problems with word finding/word order when speaking quickly (the "peanut jelly and butter sand, ah, sandwich") problem.

I did get a rash three times, once pretty extensively.  Avoiding alcohol seems to be helping this time.

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acne

cystic acne on my back (EW, that didn't go away even when i stopped it until i went on abx)

migraines

muscle pain crampey icks

shaky hands

extreme memory loss (couldn't remember the name of the med i was googling the side effects for unless i held the bottle in front of the keyboard)

and um, some neuro problems that i seem to be the only person in the world to have had... which is why i went off it, but my pdoc and neuro said they'd never seen someone have that reaction, so i should stop talking about it now.  man i babble.

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- migraines

-muscle aches

- shaky hands

- itching that comes and goes while going to sleep or waking in the middle of the night itching

- the feeling that "bugs" are crawling under my skin which then leads to the above

- WATER RETENTION that i am totally sick of

- bladder control problems

I'm pretty sure Lamictal is aging me at an astonishing rate...seriously - bladder contol problems??? ;) WTF???

aimee

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My rosacea has been worse, but I didn't think about attributing it to the Lamictal. It's always been bad (my dad used to ask me "who stepped on your nose?" but it's been awful lately.

Cognizant impairment which leads to the self-loathing during depressive episodes (I still get them, but they are not as severe)

Muscle aches, especially my neck.

Trouble falling asleep

Seeing wierd "things" out of the corner of my eye.

Acne at first, only appears mildly during recent titration.

Major problem with speaking.

Major problem with memory.

Like the rosacea, I didn't attribute breakthough bleeding with Lamictal. Also some night sweats.

Depersonalization (somewhat zombie-like).

Lots of rapid cycling, mixed states episodes at first. Not so much now.

Appetite loss at first. Not so much now.

Some dizziness.

There's probably more, I just can't remember...

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When I first started, but these have dissipated...

headaches

mouth sores

When I jumped up to 75 mg...

sore muscles (no more)

back pain (no more)

Eye twitching (has not gone away)

hot flashes (still have, but for the past few days not so bad)

intense craving for sweet foods (wish it would go away)

sleeping more - very hard to get up early in the morning

These side effects are nothing compared to the help it has given me.  While I'd rather not have any, I'll put up with it because of the benefits!  The hot flashes are probably the biggest pain; you never know when one will sneak up on you!

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Current Lamictal side effects for me: None.  BWAHAHAHAHAHA.

Side effects when I thought I could take it in the evening: Complete inability to sleep during any part of the night.

Side effects when I thought I didn't need my Neurontin alongside the Lamictal: Electric shock-like sensations, like those bugs, all over my skin.  Feels like what happens when you touch the electrical leads off of a 9 volt battery to your skin.  PDoc did not understand my analogy due to lack of a Y chromosome on her part.

So much for GABA agonist activity.

Side effects whenever titrating dosage upward (to 200 mg): Bouncing off the walls.  Not in the hyper or manic sense, but literally, bouncing off the walls while trying to walk.  Other ataxic issues too... typing speed would drop from 140wpm to 30wpm, which was very unnerving.

Side effects whenever purchasing the medication: a $150 bill for it every month.

But otherwise, you're talking to a happy camper here.  Sad thing is, I haven't seen any huge effects in stabilization or antidepressant effects, so I'll be getting a Lamictal plasma level done this week to see if I'm anywhere in the therapeutic range (God knows how they do that, since plasma clearance is so damn variable, even within the same individual). 

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Heya,

This is fun.

I love my Lamictal, but it *is* a weird one.

And I actually got levels done.

On 225mg at bedtime.

They had a reference range of 4-39 mmol/l.

On birth control, my level was 9.1.

Off birth control, it was 13.3.

Which is leading me to go off birth control.

Otherwise, no idea what raw levels tell me, if anything.

OK, let's keep going.

I never thought about the shaky hands re. Lamictal.  I just thought I got it from my dad.  Have to look at the timing there.

Tourette's eh?  Wow, that's a wild one.

--ncc--

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Yes to all above (except the tics).

Dont forget mania.

Extreme fatigue

Sleepiness w/out being able to go or stay asleep

Cough for no reason (almost a reflex- hard to explain)

Acne

Heart palpitaions

Irritability- major road rage

Loss of appetite (lost about 15lbs)

Stomach problems- all of them

I also chewed on my tongue alot

Anxiety- never had it before

Anger!

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Hmmm...well initially I had:

increased migraine frequency (I did get migraines before starting, though), which went away after a couple of weeks.

Around 50 mg:

restlessness, agitation- which went away around 75 mg??

Presently I'm at 150 mg. The entire time I've been taking it I've noticed:

mild sedation

acne- but I am not sure if this is hormonal or the Lamictal, though.

Also of interest to me, because I'm preggers:

I did not notice any truly effective mood stabilization until 100 mg. I think it took so long because of the increased hormone levels of pregnancy- I started it at around 12 weeks preg. I am curious about how this dosage will affect me postpartum, and whether its antidepressant properties will be able to put a dent on postpartum depression (which I have had after both of my other pregnancies) without an adjunct- stay tuned!

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I can't help but notice how many of these side effects seem related to estrogen deficiencies.  I wonder if Lamictal in some way lowers or inactivates estrogen? 

Poor memory

dry skin

migraines

acne (too many androgens relative to estrogens)

hair loss (again, an imbalance tilted towards the androgens, such as DHEA and testosterone)

poor sleep

night sweats

It looks like a list of menopausal symptoms!!  If I were on Lamictal, I would boost my estrogen levels as high as I could without getting breast tenderness or swelling, and see if it alleviated my SE. 

The guys will have to come up with their own solution.  I'm sure estrogen is not it!

I use bio-identical estrogen and love it.  No side effects.  I use either the Vivelle patch (pure estradiol) when travelling, or Tri-est cream, which is 80/10/10 estriol/estradiol/estrone. Estriol has been shown to be protective against breast cancer in some studies.

Highly recommend Uzzi Reiss's book "Natural Hormone Therapy."  I've read them all and he's the best, IMO.

I don't use progesterone at all, that stuff makes me feel ill.  So I take I3C to improve my 2-16 ratio, rendering my estrogen metabolites benign. 

Goddess

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Mega, I mean MEGA nail and hair growth. I was a life-long nail biter and then started Lamictal. Two weeks into it I noticed that I ripped a nail. I had never had enough nail to rip before! I noticed nice, thick, long nails. This happens with my nails and hair. I get my hair colored much more often now. My stylist has never seen anything like it. My hair grows about an inch a month. Most people have an inch in 3 months.

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I can't help but notice how many of these side effects seem related to estrogen deficiencies.  I wonder if Lamictal in some way lowers or inactivates estrogen?

A lot of things have the exact same symptoms as estrogen imbalance: excess progesterone, not enough progesterone, hypothyroidism, various other endocrine disorders, other medication side effects, puberty...don't blame low estrogen for everything!  (Oh, and PCOS has all those effects and more)

I think it'd be nice to divide side effects into transient side effects that occur when you're titrating on lamictal and ongoing side effects after being at a steady dose for a few months.  Otherwise we're going to scare the shit out of someone who might not even have gotten the SEs and could really benefit from the med.

Transient side effects:

Every time I increased the dose I got these for 3-5 days:

Headache (Advil worked)

Backache in the same place each time (again Advil helped)

Funkiness in the brain

Some racing thoughts, pressured speech and jitteriness

My eczema got a little worse for a while

The only side effect now seems to be a little fidgety-ness (bouncing my knee, moving around my office a little more than usual).  My hairline had already receded some due to Depakote, and I haven't noticed it getting worse.

Oh, and the main ongoing side effects are that I'm now calmer, my mind is clearer, I'm able to work through work problems and personal problems, I'm able to find new solutions to things, I'm not so paranoid around people, my blood sugar is tons more stable, I rarely binge, and I don't think about crashing my car into a bridge abutment. 

I'm a fan of the stuff.  I've always had excess estrogen so maybe lamictal is improving things for me if it reduces estrogen.  Or maybe lamictal just works, eh?

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ncc1701-

I do not agree with your definition of Intellectual Personality Disorder.  Personally, I want to redefine it as so:

* Inability of laymen to understand you, even though your ideas are brilliant.

* Ability of specialists in your field to appreciate all of your [insert field of specialty here] ideas and want to hire you.

* Friends looking at you as if you're a goddamn f*cking freak.

* Your parents hate you.  Unless you're lucky enough (like I am) that one of your parents is in a similar field as you.

* While growing up, your parents lack the capability to understand you.  "Why aren't you out playing like all the other boys are???" When in fact, you're coming up with culinary masterpieces that Jacques Pepin would indeed be proud of.  That actually happened to me when I was 19, as my mother didn't know when to f*cking let go.  I've actually been making my own sandwich creations since I was 2 (before I even learned how to talk, even). 

* Utter lack of physical coordination.  If I trained all year, I probably have the natural physical ability to become a champion cyclist or runner.  However, don't ever expect me to play soccer, tennis, basketball, badminton, golf, or any other sport that requires me to "keep your eye on the ball".  It's no problem if the sport just requires endurance and guts, though.

* Wait, I think I just defined the criteria for Asperger disorder and/or High Functioning Autism.  Rrrrrrrrrrrrrrr.

Loon-A-TiK-

I know what you mean by the excessive hair and nail growth.  It's been worse for me on the Lamictal, and it was bad enough to begin with beforehand.  Now if only I could gain hair thickness as well as length from my alopecia-arreata attack 2 years ago...!

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Wait, I forgot another side effect problem.  Every time I up the dose (which might be happening again from 200 to 300mg!), I get dumb as a bag of rocks.  Dumber than the bag of rocks I normally am (think a downgrade from granite to regular Baltimore cement.)  Also seem to lose coordination with my fingers.  Normally I can sustain typing ~110 WPM for extended periods (people tend to refuse to let me use their keyboards, concerned about me setting them alight... call it the long skinny fingers due to CTD), but during the week after a dose increase, I'm lucky to do 30 WPM, with much backspacing.  I'm also (quite literally!) bouncing off the walls, using them for support as I maneuver my uncoordinated and skinny ass through tight corners in my 70 year old house.

I also tend to be more forgetful during these times, due to said cement effect. 

I'm not sure, though, I could ever match the absentmindedness of my pdoc, who last week, attempted to write me an Rx for Klonopin on the "DO NOT USE FOR CONTROLLED SUBSTANCES" Rx pad.  I reminded her (as she'd done the same mistake with Provigil once) to write the Klonopin Rx on the DEA Schedule pad the clinic has... her response was "oh, of course, I'm well aware", at which point she surreptitiously scratched out an Rx on the non-schedule pad, tossed it behind her back into the trash, and wrote my Klonopin Rx on the correct pad.  The worst that would result in would be Walgreen's or CVS immediately telling me that I'd have to get the Rx re-written, but it was still pretty amusing.  She'd also written down in my medication profile that I was taking 30mg Lamictal and 200mg Cymbalta (interpret as you will).  I'm not upset, though.  Her absentmindedness is probably what makes her a more intelligent clinician otherwise (the good Lord gives, the good Lord takes...).  And at least she hasn't, say, bordered on malpractice, like a few of my other physicians (in more "physical" fields) have. =D

And yes, she does have a lot of respect for me, to the point where she's outright disappointed, if not upset, that I've retracted my lifelong decision to become a physician.  Oooooh that rhymed... yay.

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  • 2 weeks later...

I just started Lamictal 3 days ago.  I'm thinking about cutting the 25mg starter pack pill in half because I'm literally bouncing off the walls.  I'm recovering from back surgery and I've been in a serious depressive state for the last month, right after I went off taking narcotic pain medication.  Sitting around with nothing to do while your back heals didn't help things.  I have been taking just Seroquel for bp1.  Today I was going nuts and just trying to deal with a hyperness that is just plain uncomfortable.  Same thing yesterday.  I don't take the Seroquel during the day but I did yesterday and today with 1 mg of klonopin because I felt like I can't stand or sit still.  It's making me uncomfortably vamped.

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I have been on lamictal for nine months. Titrated from 25mg to 400mg. I had acne. (Little white zits on neck). Night sweats. Breaking out in a sweat from light exercise or most anything. All that is gone now. My body must have adapted. Now I just get the dumbs now and then and my left arm muscle bothers me.

All in all lamictal has helped me with depression.

fc

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This is the fourth week 've been on Lamictal and haven't noticed too much -- my sleep, while sometimes deeper, can also occasionally be restless and I'll wake up in the middle of the night more than before.  It might decrease the sex drive a slight bit.  I think it relieves some anxiety and depression.  I am on 100 mgs. now.  But one thing I've noticed -- anyone else get this?--I've had a few nosebleeds in the last couple of weeks, which I have only gotten a few times before.  Since the heat is turned off in my apartment, I don't think it is the dryness of the air.  Anyone else get nosebleeds??

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I've noticed absolutely ZERO side effects with this med.  Been on it for 5 weeks now.  I don't think I've reached quite a therapeutic level yet (100mg), but this is the first time I've tried an MI related drug that didn't give me any problems whatsoever.  ;)   Yay!

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Heya Robot,

Great!

I love my Lamictal.

And I'm left now with:

Worse rosacea (for sure.  Using metrogel/rosasol daily now).

Night sweats (which I actually don't hate, have grown used to, and recommend using scrubs for).

All the other crap has settled.

Not sure about this NuvaRing though, but that's another story.

--ncc--

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It seems like I'm also stuck with night sweats and flushing.  Hmmmm...maybe rosacea?  I've always had "emotional skin" (as one therapist put it) from my chest up to my face.  When upset, I turn red.  Now it seems kind of random when my ears, cheeks and nose get red and hot.

I seems to also struggle with a tightness in my shoulder and neck muscles and more headaches than I used to have (which, unfortunately was already a lot). 

But I still love Lamictal!

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hair loss - taking biotin & zinc for this
Hm, are you taking separate supplements for this?  And how much are you using?

My hairline at the temples has indeed receded over the past several years.  It probably is a combination of age, crazed hormones, and Depakote, but I'm just really noticing it now (probably because I'm feeling better and starting to care a little about such things).  I'm hating all the pills I'm taking and am having trouble taking my vitamins, but if it were for vanity maybe I'd be better about it.  Let me know...

ncc, so where do you get scrubs if you don't work in a hospital?  I'm getting hot flashes on and off still; not nearly as bad as last fall, just about one a night, sometimes two, sometimes none.  Even so they're a bit of a pain.

But I don't think the hot flashes are from the lamictal; looking back I now realize I've had them on and off for years.  As for the hair loss, well, given my family history, I've been expecting to go half bald eventually anyways, just hoped to stave it off for a little bit!

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Heya,

;)   Most department/clothing stores carry scrubs.

So *very* easy to clean.

The best, of course, are the ones I got from hospital laundries, b/c they're so soft from so many washings.

PS.  Loving this minus 40.  Night sweats become waqrm sleeps.

--ncc--

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I'm beginning to question whether I've got rosacea, as well. I've always had sensitive, easily reddened skin. And it did seem to get a bit worse since starting Lamictal in Sept. But this is getting ridiculous.

Earlier this week, I had to get up off my ass and go to a trade show (long story). So I had to dress up and put on makeup. Haven't been out of my house a great deal for months, so it was the 1st time in a long time that I'd worn makeup. I don't know if that set this current shit with my skin off, or? I've carefully chosen my makeup, and what I currently use has never bothered me before.

Anyway, I now feel like my face and neck are sunburned. Red with blotchy patches. Really tight stinging feeling. At times, it hurts. I've been trying to baby my skin; just rinsing with tepid water, only using a little olive or mineral oil on it, plus some cortisone cream. I live in an extremely arid region, especially in winter, so I plugged in my humidifier last night. (Usually I run it all winter, but I hadn't so far. Long story.) Maybe it (or the Klonopin I took last night) helped? But shortly after getting up, the skin thing started happening again, and now it's bad.

Does this sound like rosacea? Seems to me that whenever I'd read about it before, my skin problems just didn't seem to fit the description. But maybe now that I'm on Lamictal it does?

PS - Oh, I should say that in the past I was dx'd (by a good dermatologist many, many years ago -- I'm talking decades) as having seborrheic dermatitis. But that basically seemed to go away, hasn't been bothering me for many years. I guess what's happening now could be age and/or hormone related, too. Or set off by stress and anxiety -- god knows I've had enough the past couple months.

Sorry, this probably doesn't belong here. Just read "rosacea" in the above posts, and got going on it.

PPS - Reading the definition of rosacea here: http://www.internationalrosaceafoundation.org/ I'd say there's a high likelihood I have it. Bummer.

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Revlow, before you go too far with your self-diagnosis, hie thee to a dermatologist.  The first thing I'd suspect would be dermatitis, since you've already had it, and your skin may just have become more sensitive either because of the lamictal or just because that's where you are in life.  Remember that it resulted from the use of makeup; I'd think you'd have shown symptoms before if you had rosacea.

I'm hypersensitive to fragrances and artificial colors in creams and soaps.  I use only fragrance-free hypoallergenic hand soap, bath gel, shampoo and deodorant.  I also use unscented fabric softener and hypoallergenic detergent.  Since using lamictal I'm a little more sensitive to all this stuff, and I get more blistery dermatitis on my hands just from hot water and any irritating substance (onions, garlic, cleansers, anything with aromatics) than I used to, so I wear latex gloves whenever I get near the sink or do even light cleaning.

Remember how we can't self-diagnose our MI?  There are so many things that can go wrong with your skin that it could be any number of things.  Anyhow, let us know what the dermatologist says.  It could be that you need to get super-hypoallergenic makeup and make some adjustments with other irritants. 

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Thanks, NARS. Good points.

I left a message today at my doctor's office to find out the names of dermatologists he recommends. Hopefully I'll set something up soon.

I've been super careful most of my life -- I just have very fair sensitive skin so I have to. No frangrance in anything for starters. Hypoallergenic everything. I hadn't had problems with this makeup before, but I have noticed similar reactions to some products since I started taking Lamictal. A favorite cream I've used for about 2 years? Can't use it anymore; it irritates my skin and causes me to break out. Weird.

My skin is doing a bit better today. Another night with the humidifier and a Klonopin, and I slept in very late. I think that makes a big difference.

Thanks again for your calming thoughts! I appreciate hearing your words of wisdom. You're absolutely right. I need to see someone on this.

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Hopefully the dermo can give you some topical something to put on when your skin acts up.  I was all pissed off last week because my thumb and forefinger on my left hand broke out in blisters and I couldn't remember touching anything irritating.  But then I realized I'd gotten a little cavelier about rinsing dishes and doing stuff around the sink without gloves.  But I've got a cream I can use during the day and an ointment at night, so aside from having my fingers bandaged at night it's really not so bad.  I just need to be more careful than before.  I also get eczema on my ears (eww!), but he gave me a marvellous cream for that, too.  It's also possible that it'll get better with time, but for now I'm happy to live with that one minor side effect.

Good luck with yet another doc!

edited to add: I generally need to do the night thing for only a few days.  My fingers are  already much better.  I don't want to get you worried!

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Thanks, NARS. Good example.

One of the things that got me thinking about rosacea, even before this latest episode, is that my skin has been redder since starting Lamictal. Other people have noticed it too. I've always had a tendency to be red on my chest, and at times my face. But now, in addition, I get very red down the sides of my neck, which fits part of the definition at the International Rosacea Foundation -- and I've got some of the other symptoms. But, I definitely need to get some expert eyes on this.

One of the things that *may* have helped calm my skin down, in addition to the humidifier and taking Klonopin, is a weird one. I've used it in the past a few times when my skin has gone nuts. Monistat vag cream. Yes, Monistat. Sometimes, it seems to help. Whatever the reason, I am glad my skin has calmed down. It was getting painful. ;)

Thanks again for all your info.

(Sorry for the threadjack)

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Heya revlow,

Sounds much like rosacea.

Not sure why antifungals work for you; but hey, if it helps -- no harm in it, that I can think of.

Yah my dad has it, many of his sisters and brothers, and lucky lucky me.

I use Metrogel at night and Rosasol during the day.

Metrogel is metronidazole (AKA Flagyl, what you get Rx'd in pill form if you get BV or trich).

Rosasol is Metrogel with SPF15 sunblock in it.

Works for me, unless I really am out in the sun too long, like last weekend, and then I have to take a Benadryl (and a nap).

--ncc--

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Thanks, ncc.

Yes, I am unfortuately very familiar with Flagyl! Took it once for trich. Not great, but not that big a deal either. Later had to take it for 2 types of amoebas when I lived in Mexico. In HUGE amounts. Been so long (almost 30 years now), I don't remember the details, but I do know it was some astronomical dose compared to what you have to take for trich. Seemed like I was on it forever. It made me sooooo ill that I'd get nauseated just at the sight of my purse, where I kept my meds.

I later got hepatitis and paratyphiod fever. In comparison to treatment with Flagyl, I would rather get either hepatitis or paratyphiod fever again. Or almost anything. (Shudder) I didn't want to take it initially due to my prior experience, but the docs in Mexico put it bluntly: Either take this, or in approximately two years, give or take, you'll have a hanging liver off your side. And then die. So I took the nice med.

How is it topically? Do you get any of the same SEs through the skin? I imagine not, but worth asking. And just out of curiousity, why does an amoebacide (sp?) work for rosacea?

Thanks a million your input!

revlow

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Heya revlow,

Yah Flagyl can be very icky at high doses.

No s/e to speak of with topical use, except the logical ones of skin irritation and rare allergies.  The link in the next post points to the raft of other s/e that have shown up in prople using it topically, basically anything you can think of.

Thought to work (temporarily anyway) b/c it's also anti-inflammatory, and (I think, just IMHO) also helps with (especially for guys or very hairy women) folliculitis that can go along with rosacea.

Here's a patient handout.

For those of us with IPD, the next post is parts of the monograph.

--ncc--

Patient Education

METRONIDAZOLE - TOPICAL

IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

METRONIDAZOLE - TOPICAL

(meh-troh-NID-uh-zole)

COMMON BRAND NAME(S): Metrocream, Metrogel, Metrolotion, Noritate, Rozex

USES:

This medication is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.

This medication is an antibiotic. For the treatment of rosacea, metronidazole is believed to work by decreasing swelling (inflammation).

HOW TO USE:

Use this medication on the skin only. Wash and dry your hands before and after applying this medication. Wash and dry the area to be treated. Wait 15 minutes, then apply a thin layer of medication usually twice daily, once in the morning and once in the evening, or as directed by your doctor. Wait 5 minutes before applying cosmetics.

Avoid using this medication around the eye area, unless directed by your doctor. Watery eyes or tearing of the eyes may occur if this medication is applied too close to the eyes. Avoid getting this medication in your eyes. If this occurs, rinse your eyes with large amounts of cool water.

Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day.

It may take about three weeks before any improvement is seen, and up to nine weeks for full benefit. If no improvement is seen after three weeks, consult your doctor.

SIDE EFFECTS:

Stinging, burning, skin irritation, dryness, redness, metallic taste, nausea, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if you have this unlikely but serious side effect: tingling or numbness of the hands and feet.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.

If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS:

Before using metronidazole, tell your doctor or pharmacist if you are allergic to it; or to other nitroimidazole antibiotics (e.g., tinidazole); or if you have any other allergies.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood disorders (blood dyscrasias).

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Breast-feeding while using this medication is not recommended. Consult with your doctor before breast-feeding.

DRUG INTERACTIONS:

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: "blood thinners" (e.g., warfarin).

OVERDOSE:

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. This medicine may be harmful if swallowed.

NOTES:

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in those cases.

Avoid certain triggers that may worsen rosacea such as excessive sunlight, wind, hot beverages, spicy foods, alcohol, and extreme cold. Discuss with your doctor.

MISSED DOSE:

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:

Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. If using the lotion, do not freeze. Do not store in the bathroom. Keep all medicines away from children and pets.

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ncc:

Wow! Thanks for all the info.

I'd forgotten all about its anti-inflammatory properties. I know I'd been told about this a couple of times (either with kids at the doc's, or dogs at the vet's, or???). Always blew me away when I'd hear this. Such a nasty, nasty drug has anti-inflammatory properties? Apparently so. Go figure!

Thanks again. Got some reading to do.

Your IPD pal,

revlow

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  • 2 weeks later...
Guest just me

intense craving for sweet foods (wish it would go away)

I thought I was the only one.  Since I upped it to 100 mg I have been binging like crazy.  it's so embarrassing.  I'm going back to 50 mg.  I'm not hungry, jyst fatigued and it makes me crave sweet things.

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<threadjack -- sorry, but since we talked about this before here, figured I might as well do it again>

Went to my doc today for my every 2 wk Lamictal check-up. Asked about the possibility of rosacea. My face/neck were pretty okay this morning, not red, only a little blotchy. Explained to him how bad it has been. There was even one night when I couldn't get to sleep, my face was hurting that much. Asked him if he could prescribe something like Metrogel. Practically begged him. Nope. He wants me to come back in when it flares up again, said to tell the front office staff that he wanted me to do this, and to come into the office immediately. Which would make sense if it weren't for 1) it's all but impossible to ever get past his gatekeeper in the front office (I tried to explain the situation to her as I was checking out, to give her a heads-up, but it didn't seem to register); and 2) he only works 3 days a week. So if I get a flare-up and it happens to occur Mon, Tues or Friday during office hours, and I can get past his front office, then he might do something. Shit.

I also forgot to ask for the names of dermatologists, so I screwed up there. I know he's just being a good conservative doc, but hell...my face stings.

</end threadjack>

PS - Later...

Are there any easy-to-find (remember, I'm in a remote area) OTC products that might help? I'm bright red and stinging to the hilt and, of course, it's after hours so no running in to the doc's to show him. I feel like I've been under a sun lamp too long. *

Seems to me I've read that topical cortisones can actually cause more harm than good with rosacea.

What helps? Thanks. (Once again, sorry. I guess I should have started a thread in Miscellaneous Side Effects.)

* (Going by memory since I gave up sun lamps in the '60s -- or even trying to tan -- after far too many bad sunburns. Finally resigned myself to the fact that even though I lived in So. California and the surfer girl look was "it" at the time, I was fair skinned. And always would be. This was back when having skin the color of rich Corinthian leather was the norm; I was looked upon as a freak, but so be it.)

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Heya revlow,

Guess he's looking to see SJS, or whatever, drug rash, bla.

At any rate.

In an airport once, cream all packed, icky rosacea attack, bumpy and itchy oh my.

Benadryl from the convenience store helped, so I carry it around now, although I feel a bit stoned whe I take it so I try to hold off til bedtime.

Worth a try.

Still looking around for other OTC stuff that can help, but no luck yet.

Let me know if *you* find one??

--ncc--

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Thanks, ncc.

Yeah, I don't know what his thinking was. Usually he is very trusting about my instincts, but I guess this is one of those "other" situations. "I need to see it, before I know." "I'm from Missouri, the 'Show Me' state." Whatever. ;)

I can't imagine he'd be thinking SJS. I described it to a "t" -- face, neck, ears. Stinging, burning. Redness, raised patches. Didn't describe lesions, blisters or anything to do with mucous membranes. Oh, well.

Thanks for the suggestion; good idea about the Benadryl. I'll see if I can find any in my house. (Trying to avoid going out in the snowstorm if possible; will go to the store tomorrow.) Haven't used it in awhile. Generally doesn't do a lot for me though. In the past I'd have to take a shitpile of it.

Did take a Klonopin almost 5 hrs ago. I guess maybe that helped a little? I know in the past couple hrs I'm noticing it stinging more, so I guess there was a bit of a stretch when it was calmer? I think. Maybe.

Just looked in the mirror and I am bright red and splotchy. Quite a sight. That plus my receding hairline. What a looker!

Maybe I should get the roommate to take some photos of this, just in case I can't manage a flare-up during the doc's office hours. Though it probably wouldn't make a difference; I bet he'll still need to see it in person.

Thanks again. Am very grateful for your all your help.

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Just checked and the roomate has fallen asleep early. (Glad for him; he could use it.) So I'll just have to hope I get "lucky" and either have an attack during the doc's office hours, or some other time and severely enough to be able to document it photographically. Pish!

Think I'll take another Klonopin and call it a night.

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Heya revlow,

Dermatologists seem to really like photos.

So next time maybe you can take a pic for your show-me doc.

Internists are fun.  We get annoyed sometimes, like we're their residents or something.  So, sometimes we (of course not I) screw with their minds.  Like we order every test known to man, or no tests at all, before they see the patient, and see what they do -- how many tests they order ;) .

But here, they're by referral only , so we have the power.

Have a good sleep.

And avoid oil-based cosmetics.

:)

Yours in Lamictal-associated red-bumpiness (see how smoothly I got us back on-topic?),

--ncc--

PS.  Carb craving.  I'm a meat-and-cheese girl, but now carb-craving, which is weird and may or may not be a s/e.

--ncc--

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LOL.

Now we've got something else to add. All our assorted MIs, plus IPD. And now LARB (Lamictal-associated red-bumpiness)! LARB...it's got a ring to it, eh? (Not!)

Good night, my fellow LARB sufferer. And thanks!

rev

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  • 1 month later...

Umm...gross problem...terrible gas!  And bloating and water retention.  Not pretty.  And this was when I was on it for less than a week.  I had actually started feeling good (doc wasn't sure that it was the medication, as I hadn't been on it for long) but I became too anxious about gaining weight and creeped out by the weird GI side effects so I stopped taking it.  Dunno if I'll try it again...

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That's a bummer, devon.  My gastric & lower digestive distress went away after a few weeks; most lamictal side effects do the same.  I had to stop eating meat for several weeks and go on a pretty bland diet, which helped.  But once I'd adjusted, I had absolutely no digestive symptoms, headaches, bloating, or muscle pain.  It's the only psychiatric medication I've ever taken that has no side effects for me at a therapeutic dose.

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Like NARS said, most side effects are temporary with Lamictal. Might be worth another shot, especially since you've given it so little time.

One thing not to worry about: Lamictal is considered weight neutral. Weight gain is not likely.

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Hey JBella,

Your experience sounds an awful lot like my experience on Lamictal.  Tired-check. Short fushed, bitch-check.  Out of the blue sweating buckets (especially during sleep)-check.  Layers of skin peeling off, itching until I bleed...even with daily moisturizing-check.  Body jerks (ticks?)-check.  MIGRAINES from hell-check.  Blurred vision/extreme dry eyes-check.   

When I was on Lamictal, I simply felt ill.  Just sick.  It was really hard to get my pdoc to understand how hard that medication was on me.  He simply didn't believe me.  Hey doc...I'm the one taking the fucking pill...I'm the one feeling like death...It ain't working...I'm done...  I honestly think he feels like Lamictal is "the wonder drug".  I know that it probably is for many.  It just wasn't for me. 

Wow, can I ramble. ;)

aimee

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I got the starter pack from my pdoc.  Started on 25, just went up to 50 a week ago.

At 25, the side effects were

a pain on my back on the right halfway down, it started about an hour before I took my pill at 12:30pm.  It went away after a week and a half.

loopy, out of it feeling the first few days and every so often

a little dumbing down...couldn't remember some words

at 50

trouble sleeping.  Some nights I can't fall asleep until 3am, 6am.  Once I go into bed, I stay up for about an hour, with songs running through my head.

Noises are louder to me.  Even no noise sounds like noise.  Doesn that make sense?

fidgeting with my hands. 

no appetite.  I don't really eat until dinner.  Force myself to eat a little during the day.

out of it.  Today at my tdoc, I felt like I was going to jump out of my skin and was having trouble speaking.  Almost wanted to leave the room because I was so uncomfortable. 

Today, I started having pains in my elbows.  They come and go, sometimes one hurts and the other doesn't but sometimes, like right now, both hurt.  Feels like a bruise.

So far, I really like it.  I'm not sure what my diagnosis is.  I have been depressed for years and this drug is working really well for that (except for an 3 day episode last week).  I also have a lot of anxiety but it doesn't help that.

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Magnolia, I'm also on my starter pack and it sounds like we started at the same time.  Also have depression/anxiety.  Are you also taking it at night?  I haven't really had too many side effects but I notice even if I'm exhausted I can't fall asleep.  Like almost out of body experience cause my whole body is relaxed and my brain seems like I'm gonna go to sleep but I don't.  WTF?  Has anyone told you this will go away! 

My brain does feel a bit mushy - although that might be from lack of sleep.

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I've been taking it at 12:30 in the afternoon.  I've been hesitant to change that time because I still can't figure out if it makes me sleepy or energetic.  It changes everyday.

My problem is my body is tired but my brain isn't.  The only thing that helps me fall asleep is drinking several glasses of wine before bed.  I'm going to talk to my pdoc about it today.

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Speaking of side effects, yesterday I got a

MIGRAINE! 

I've never had one before and holy cacti, does it suck.  A shot of Imitrex later, and the tension headache hit like a trunk.  So badly that the doctor and chiropracter couldn't fix it, and I couldn't open my eyes.  My shoulders and neck were so tight, my shoulders were stuck in the up position.

Thank goddess for little white pills.

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Oh JBella,

I'm so sorry to hear that!!!  I really struggled with Lamictal.  I wanted it to work so badly.  I kept thinking...it works for so many...why am I so sick?  It didn't help that pdoc didn't think my problems where being caused by the Lamictal.  Funny how the migraines, and all my sick feelings stopped when I stopped Lamictal?? 

How long have you been on the Lamictal?  Is this the first migraine?  I hate to hear anyone feel the way I felt on that medication.  I hope you feel better very soon!

Feel free to PM me if you ever need to bitch about it...believe me...I spent many days bitching about Lamictal!! 

aimee

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Thanks Aims,

I've been on Lamictal for a month and a half.  Sound familiar?  "This is a great drug.  There are practically NO side effects."

And my normally shiny, healthy hair is icky and coarse.  I'm going to try the zinc selenium thing someone suggested.

And I'm super cranky.  Probably the migraines, but I'll blame it on the Lamictal.

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I like Lamictal for the most part, except that the aftertaste is EL YUCKO. Yikes. I try to take it with a ginormous swig of water so that it doesn't rub up against my tongue or throat for too long. lol. GRODY.

It's really helped my mania a lot... though I miss my mania. *sigh*

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I'm not even sure lamictal helps me....so much traumatic stuff has been going on it's hard to tell....but i DO know that the aftertaste or the taste you get when it gets stuck on the back of your tongue for a second is  god awful.  I have to take this with orange juice or milk to help.  Why can't they just gel cap this shit like effexor???  GAG! ;)

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How To Take Lamictal Without Getting The Bitter Taste

1. Take a swig of milk or yogurt or a bite of anything with fat or protein in it.  Chew well if necessary and make sure your mouth is full of it.

2.  Put your lamictal tablet between your teeth, don't let tongue or lips touch it.

3.  Wash it down with water (or if you really want to be sure of it, more milk).

Seems that substantial food blocks the bitterness from reaching the tastebuds.  Soda, juice and stuff like that don't work for me.  It has to be either fatty or protein-ey.

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I've been taking Lamictal for about a month. No rash thank god & it's keeping my mood up off the floor.

I'm not sure how many things I can attribute to Lamictal, rather than my other meds, but I do know that my vision is blurrier.

I get irritated very easily.

I've got really dry skin.

Forget words and often stumble through a statement b/c I can't get the words I want to use. I could be a witty person otherwise!

Tremulous - my brother & housemate pointed out how frequent it is lately.

And today I had some breakthrough spotting for the first time ever. Geez it gave me a surprise. Not impressed  ;)

I like Lamictal for the most part, except that the aftertaste is EL YUCKO. Yikes. I try to take it with a ginormous swig of water so that it doesn't rub up against my tongue or throat for too long. lol. GRODY.

<{POST_SNAPBACK}>

yuk, glad I'm in Australia then...the one's I have taste like berry's if I let them sit on my tongue. I almost don't want to swallow them!

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What????!!!!

You mean to say that the horrid migraines, the edgy/manicky/irritable/what the fuck is this grrr! feeling, my low back pain, the fact that I keep waking up at nigth, and the crazy carb cravings could all be because of the Lamictal?

OH NOOO...please no. IT WORKS...well, for depression anyways.

Seriously, is any of this on the PI sheets? except for "headaches" (no relation to my full blown migraines, surely...)

Hey is this as good as it gets? we get to choose between mood shifts or drug side effects? I had great hope for lamictal's lack of side effects, and I guess I missed the blatantly obvious...oh well.

Oh, I get thirsty a lot too.

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Stop for a minute, and look around & locate the button labeled DON'T PANIC!!  There, feel better?

These are all transient side effects.  I had every single one of them, plus terrific nausea, when I started lamictal.  They got much better after the first 4-5 days after each dose increase, and as the doses got higher the SEs got more mild.  Once I reached 200 and adjusted to it all of the side effects disappeared completely.  This is the only medication I've ever been on that has no side effects now that I'm where I need to be.

I know the edginess and irritability may feel like mania or mixed state, but know that lamictal does not usually cause mania.  Many people posting here report mania but mania is very rare as a SE of lamictal.  The reality is that it's not a good initial med for acute mania, as it's activating at low doses.  It's a great med for the depressive phase of BP or to switch to if you're already stable on another med but don't like the SEs of the old med.  And remember that for most of us the mood stabilizing effects of lamictal don't really kick in until the higher doses.

I love my lamictal.  Recently I made the mistake of going off of my AD even though I was doing great.  For me, for my personal form of BP, I apparently need my wellbutrin.  But with lamictal and wellbutrin I've done great.  I'm going back to that now and look forward to a productive and happy life.

edited to add: and another thing to remember is that when you have a thread about side effects, the people who tend to post are those who have not been able to tolerate the medication.  Consider that for every person who finds a med intolerable, there are perhaps hundreds who love it.

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Heya,

heyaheya.

What NARS said.

This was a thread b/c here were *so many* mixed-up threads about Lamictal and ... whatever.

I'm (and others are) curoius about Lamictal s/e.

It's a weird and wild friend, this drug.

As with any drug, try it and see.

And talk with your doc(s) if there any ?side effects.

For me, I'm willing to take *whatever* it hands me, as long as it beats *fucking bipolar.*

IMHO.

--ncc--

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Guest Just me again

I think too many of you read way too much into the side effects... how many other drugs are you on? That needs to be taken into account as well. I have been on it for 9 months now. Lamictal is a wonder drug. It just might take your bod a while to get used to it. For me, my side effects included:

some weight gain

no appetite - yet cravings for bread/sugar/candy all the time

fatigue

anger and irritability

some paranoia.

but everyone is different. I remember my life before Lamictal and it was terrible... i wanted to disappear everyday. Now I want to live. You just have to weather those initial doses and months and you will make it. Don't give up guys, it is worth it.

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I think too many of you read way too much into the side effects... how many other drugs are you on? That needs to be taken into account as well. I have been on it for 9 months now. Lamictal is a wonder drug. It just might take your bod a while to get used to it.

Wonder drug? Yes and no. For me it has been.

For others, it can be a nightmare. If you go to Lamictal needs to go, how do I convince pdoc? you'll read of Helena's ordeal.

If you read through the whole thread, you'll see the stats from the PI (courtesy of Navy's diligent research).

It's too simple to say that it's a "wonder drug" and that those here with problems are reading "...way too much into the side effects".

Yes, it can take a while for our bodies to get used to it. It did for me, too.

I'm glad it's working for you, and grateful it is for me. But there are others here who have real problems with Lamictal.

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Oh, help! I wasn't noticing anything out of the ordinary since I started Lamictal (now upping and downing in between for technical reasons, I'm only at 150mg.day divided dose and still titrating upwards).

I hadn't noticed feeling better but also not worse. As for low back pain (bursts into hystrical laughter and can't type for few minutes).

Used to have occasional rosacea, and haven't had any in ages, come to think of it.

Hair loss??? (Preferring not to contemplate this as I already had hair loss.)

The only thing I wondered about ever so slightly, was carb cravings. Nothing anything like what I got from Paxil or a trillionth of what I got from Nardil, but definitely harder to resist than before. And in fact , I can tell I've gained about 10 lbs from when I really started titrating up (though I won't step on a scale).

I'm starting to feel I should NOT read about med side effects as I have very strong side effects from threads-about-med-side-effects. I'm going to be looking for ALL these possibilities now.

(Now how to find a placebo treatment to compare with? Maybe someone should occasionally post a thread with all imaginary side effects . It would create a control group, and we suggestible souls could see how many symptoms we identify in ourselves before debriefing.)

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I, for one, want to say thanks Revlow!! Cudos for standing up for those that had a shitty experience on the Lam. ;)

Not all of the former Lamictal users found it to be the perfect little wonder pill. We didn't just imagine our side effects. We didn't just pretend to have horrible problems. We didn't suffer for months as our pdocs scratched their heads and looked at us sideways, never wanting to think, or admit that it could possibly be caused by the precious, precious, pill Lamictal.

Too bad docs...you don't get to get off that easy. It isn't a wonder drug and it isn't going to work for every effing bipolar case that walks into your office. Wouldn't it be all sunshine and rainbows if it worked that way. All pdocs could be happy and all BP patients would be cured. On the the next brain cootie...

Like Revlow said...just because Lamictal is a wonder drug for one doesn't mean it is a wonder drug for all. I am thankful that it helps so many out there. I'm just bitter because it put me through hell for EIGHT months. Not a measly month people. I didn't give in that quickly. I gave it a champs try. I put up with a hell of a life for eight months and honestly didn't know who I was for EIGHT months on that shit of a medication. I considered myself more effed up ON Lamictal than an unmedication PBII OFF Lamictal. Yeah, it didn't like me.

I'm just saying that there are the rare folk out there that have the experiences that I, and the others have had. We have a hard enough time getting our own pdoc's to believe us. Plain and simple Lamictal does not work for all people...people...that's all I'm saying.

Off my soap box.....

aimee

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Been on it since I was diagnosed last April. I have had NO side effects due to it. It took about three months, but then I stabilized (from hypomania/irritability). since then, I have had three days where I lost it and blew up at my wife. Other than that, no issues at all. It is the only thing I'm on, 300mg. Love it.

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Wow, I was lucky, which was lucky: Already bailed on depakote and Lithium and a long list of ADs

I had/have absolutely zero physical side effects (had cognitive impairment on both depakote and lithium). I have had some nasty mixed states after every dosage change. I can't say that I'm all better but it has vastly improved the quality of my life overall.

quote name='ncc1701' date='Jan 23 2006, 08:38 PM' post='106980']

Heya,

My (made-up, not in the DSM just yet) Intellectual Personality Disorder compels me.

There are *so many* threads about Lamictal and its side effects, not all of which are on the PI or monograph.

Seems to me that those of us on CB taking this weird and wild medication would wonder about a lot of them.

I *would* post a poll, but this free-form is better for now,and if it looks fairly consistent I'll think about a poll.

I'll start.

Sedation.

Acne.

Muscle pain.

Worsening rosacea.

Night sweats.

Breakthrough bleeding.

OK, now *you* go.

--ncc--

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Ok. I can stop bitching for while now. The side effects are easing. The huge thing is that I still can't sleep without having ravaging nightmares. And my skin and weight gain.

Since people seem to think that the weight gain is due to water weight, so I've been consuming mad quantities of water and cutting down on soduim. I have lost about a pound a half.

I'm taking zinc and selenium and my hair is back to soooo beautiful. ;) And due to overlotioning my skin is smooth and pretty.

No more hot flashes, the muscle aches are almost gone except for my neck.

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I have been on Lamictal for a year now titrating up to 400mg then down to 350 mg. I had most of the typical symptoms that have been listed in the previous posts, but they went away. Now I have:

Slow thinking (which kinda sucks)

Sun sensitivity

See things out of the corner of my eyes

Sweating

Tiredness

The good effects of the Lamictal outweigh the bad side effects for me.

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I started Lamictal about 5 weeks ago (based largely on the good reviews on the boards here--well, more or less good reviews!) I'm up to 75 MG/day as of today, and amazingly, I've had few side effects so far...hope that continues. Plus, I do believe I feel better.

Here's what I've had...

A few small skin irritations (i.e., itching and small welts) when trying new lotions on my hands. Didn't seem to be a real rash...but I watched carefully. Nothing in the areas where it's supposed to be dangerous, thought.

Last night, I had a stomachache and diarrhea (sorry, but I did.) I rarely have that..but I don't know if it was the Lamictal or not.)

A few muscle aches when I started. However, on the opposite side of the coin, horrible tension pain in my neck and back seemed to disappear when I started Lamictal.

As for sleep effects...I think I'm actually sleeping BETTER on Lamictal, but not excessively.

All in all, I certainly can't complain. I still wonder what will happen at the higher doseages, but so far, so good....

CeruleanBlue.

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  • 3 months later...

I'm tapering off Lamictal now, to see if it has been standing in the way of Wellbutrin working as well as it has in the past. I decreased from 100 to 50 last Thursday, and today (Monday) I've got some massive anxiety going on. At first, I thought it was my usual crazy, but it feels different than the norm, and much more acute. It's close to the anxiety I get with SSRI withdrawal, without the mood/rage swings, or the electric shocks or dizzy spells.

I'm jumpy with noises and sounds, and my skin feels a little achy. It's all improved as the day has gone on - maybe food/klonopin has knocked it down several notches.

After reading everyone's posts, I'd like to second many of the lamictal side effects. For a long time, I wasn't thinking these were from lamictal, since I've recently been diagnosed with two autoimmune diseases, both of which could cause the same set of symptoms. In retrospect, many symptoms listed below started when I began taking lamictal, nine months ago. It could be coincidence, since everything seemed to hit at once, but here goes. I've bolded the ones that I think are most likely to be lamictal-related:

acne - the return of my cystic acne

hair loss - thinning, and some loss at temples

aches and pains, especially back pain and neck pain (have never had in my entire life - someone mentioned feeling like they began to age rapidly. That's how I've been feeling). Random, fleeting joint aches.

really stupid when I started, continuing memory issues and...more dumb than I used to be

hot flashes

fatigue

extra fidgety (from aches?)

arm muscle pain - can't sleep on my arms, and it hurts to raise them above my head for more than a few seconds

craving for sweets and, sadly, weight gain

staring off into space a whole lot more than ever before...sitting in a chair and staring more frequently.

Again, quite a few of these could also occur with the autoimmune conditions. Still, I can't wait to see what happens once I'm off the lamictal - it will feel good to remove one of the variables.

I did have headaches and nausea when I started lamictal, and again when I increased it each time, but those things went away. I don't know if the stupid went away, or if I just got used to it. I sure hope it went away, since I was way stupid for many weeks, and ended up dropping the classes I was taking, since I performed so poorly.

Lamictal did help my depression, in a new way. It said to my brain, "Hey - look over there! See how the sun is falling on that tree?" It was like being a baby, but not in a particularly disturbing way. By the time I started thinking again, I'd have forgotten what I was thinking about.

So, it turned off part of my brain. Since my brain was busy thinking/feeling horrible 90% of the time, this was a nice change. And, since the parts that were off were off, I didn't miss them as much as you would think. It was like...Flowers for Algernon, for at least a month or two. Then, I started experiences stretches of days where I wasn't crying hysterically. It did end up antidepressing me, but not as effectively as some of the other meds. Like, I never got my motivation back. My apathy remained pretty much intact, and the things I used to enjoy didn't become much more enjoyable. Aside from not feeling blistering pain in my soul as regularly as I had before lamictal.

I consider lamictal to be my "back pocket" anti-d, but hoping I'll do well off of it for now.

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these have been my "side effects" from lamictal:

i stopped biting my nails. i am positive it was the lamictal. since i hit aroung 200mg of the stuff i reailzed that i had suddenly broken a nail, after having been a lifelong nail biter and had failed at my several attempts to stop. it had to be the lamictal, there was no other explaination.

my hair also grew a lot. i suddenly had even more hair than usual (i mean head hair). i always had lots of thick hair, but now my hair was even thicker.

too bad it is falling out now due to topamax. i need to start a hair/nail formula to counter these effects and help my hair!

my nails still look great. i've never had the urge to nail bite since. remarkable.

loon

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I went off my Seroquel after upping Lamictal to 150mg. I just forgot to take the Seroquel for several days, then when I did take it, I couldn't handle The Zombie. I don't miss the carb cravings, and I've been drinking a lot less alcohol.

So here I've been thinking that in addition to being hypomanic for the last 2 months that I've been going batshit crazy, but perhaps it's all just side effects...

- hallucinations: people watching me, cars following me, bugs on my ceiling, etc.

- extreme anger and violent tendencies (not acted on, but it scares me)

- irritable as all hell

I'd rather be irritable and angry than depressed. At least right now.

Other side effects:

- acne

- rosacea?

- can't sleep

- food doesn't taste as good as it used to

- nice case of teh stupids

- super distracted

- can't concentrate

- short-term memory has gone to crap

I'm seeing the pdoc tomorrow. I love this mini-high, but it's getting a little destructive.

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One thing nobody mentioned before: dandruff. Maybe not causing it, but _noticably_ worsening it at 100 mg and higher. Going off Lamictal makes dandruff lessen noticably, but it's not worth it.

Severe fatigue, severe problems with finding words - well, I have those since adolescence (I'm in my 30s), even without any medication. I guess somebody secretly slips Topamax into my food ;-)

Worsening of ADHD - maybe. I can't measure that stuff. One's for sure, it didn't improve. Even with sulpiride (a pro-dopamine agent) or desipramine (noradrenalin reuptake inhibitor).

Acne, dry skin - can't tell, I had dry skin before Lamictal.

Total loss of religiosity - I don't even miss it, just as if some brain part was surgically removed. But it may be unrelated to Lamictal, as I had major life changes before starting it. But if it's related, I demand all far right in this country (not the US) is routinely prescribed Lamictal, with regular blood level monitoring to ensure compliance.

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Total loss of religiosity - I don't even miss it, just as if some brain part was surgically removed. But it may be unrelated to Lamictal, as I had major life changes before starting it. But if it's related, I demand all far right in this country (not the US) is routinely prescribed Lamictal, with regular blood level monitoring to ensure compliance.

Temporal lobe abnormalities are often associated with hyper-religiosity, and Lamictal tends to exert an anti-kindling effect in that area.

Persnaps this explains, maybe...?

Y'all can debate the point while I go find my keys. I should get back by next week.

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Just titrated off of lamictal myself. At highest dosage i was at 300 mg in the morning, so maybe thats why my side effects were somewhat different.

back spasms (especially bad when air pressure changes where happening)

problems speaking sentences in order

when i fist went on it and got to 300 wife said i was doing a bit of the tourette thing in my sleep, as well as twitching

never got tired or sedated

no rashes

MAJOR MUNCHIES

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