Iceberg Posted March 12, 2017 Share Posted March 12, 2017 So right now I'm on 20x3 adderall. I tried adderall XR but it didn't have the same effect...but I'm starting to get "crashes" between adderall dose. Does anyone think vyvanse would be better/last longer than adderall ER? Also what would be the equal dose from adderall 60 ? Link to comment Share on other sites More sharing options...
mmaryland Posted May 29, 2017 Share Posted May 29, 2017 On 3/12/2017 at 5:45 PM, Iceberg said: So right now I'm on 20x3 adderall. I tried adderall XR but it didn't have the same effect...but I'm starting to get "crashes" between adderall dose. Does anyone think vyvanse would be better/last longer than adderall ER? Also what would be the equal dose from adderall 60 ? So you are starting to feel the crash between the IR doses, whereas before you only felt this with XR doses...? Vyvanse is slightly a different medication, but it does have the long duration for sure. Vyvanse, at the proper dose, will last longer than adderall XR. Maybe since you are on 20mg tid, perhaps he would convert over to 50-70mg vyvanse or Adderall XR 30mg 2x AM. In each case I think the doctor might Rx small amount of instant release meds to be used throughout your initial treatment with the XR medication. I have been on them all, except daytrana and desoxyn, and have come home to Dexedrine Spansules and Dexedrine Tablets. With dexedrine, tablets, i get no crashes throughout the day. I don't get come-downs at all even if I take a few too many on the rare occasion. On another note, the Dexedrine Spansules provide very smooth, reliable, and consistent coverage through the patient's day. I found my way back to Dexedrine because I was done with any and all side effects I had with my previous medications, and have been very happy with Dexedrine since being on it for about 9 months now. Some new brand name meds just came out that are similar to adderall with various time release mechanisms, but if you havent tried the dexedrine spansules, i highly recommend them in terms of inter-dose crash and overall side- effects (I can actually have an appetite on it, who would have thought) Zenzedi - new brand name for dexedrine/dextroamphetamine IR http://zenzedi.com/ Evekeo - somewhat different composition of amp. salts than regular adderall https://www.evekeo.com/ Adzenys XR ODT - sublingual administration http://adzenysxrodt.com/ Link to comment Share on other sites More sharing options...
browri Posted June 20, 2017 Share Posted June 20, 2017 @Iceberg To convert we must understand a few things. Vyvanse is dextroamphetamine bonded with L-lysine. So to figure out how much Vyvanse we need, we have to look at the Adderall dose. Adderall is about 75% dextroamphetamine. So if you're taking 60mg of Adderall per day then about 45mg of that is dextroamphetamine. From there you can take Vyvanse doses to roughly match what that would be. You can take a Vyvanse dose and multiply it by .2948 to determine how much dextroamphetamine is in the dose. With this being said, you would have to take like 150mg of Vyvanse to get 45mg of dextroamphetamine. That's a whole lotta Vyvanse. 0_o However, Vyvanse's release mechanism is better than Adderall XR or the Dexedrine Spansules. You may find that you need less Vyvanse than your Adderall dose would indicate. Link to comment Share on other sites More sharing options...
JustNuts Posted June 22, 2017 Share Posted June 22, 2017 On 6/20/2017 at 7:23 AM, browri said: @Iceberg To convert we must understand a few things. Vyvanse is dextroamphetamine bonded with L-lysine. So to figure out how much Vyvanse we need, we have to look at the Adderall dose. Adderall is about 75% dextroamphetamine. So if you're taking 60mg of Adderall per day then about 45mg of that is dextroamphetamine. From there you can take Vyvanse doses to roughly match what that would be. You can take a Vyvanse dose and multiply it by .2948 to determine how much dextroamphetamine is in the dose. With this being said, you would have to take like 150mg of Vyvanse to get 45mg of dextroamphetamine. That's a whole lotta Vyvanse. 0_o However, Vyvanse's release mechanism is better than Adderall XR or the Dexedrine Spansules. You may find that you need less Vyvanse than your Adderall dose would indicate. That is inaccurate, Adderall doses can be converted to Vyvanse doses at approximately 40-50% equivalency. 30% is flat-out wrong. Please see my posts in http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/, especially http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/&do=findComment&comment=934983 and http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/&do=findComment&comment=935167. Link to comment Share on other sites More sharing options...
Iceberg Posted June 22, 2017 Author Share Posted June 22, 2017 Regardless of the exact number I get the point...adderall might have more punch at top dose than vyvanse Link to comment Share on other sites More sharing options...
browri Posted June 22, 2017 Share Posted June 22, 2017 8 hours ago, JustNuts said: That is inaccurate, Adderall doses can be converted to Vyvanse doses at approximately 40-50% equivalency. 30% is flat-out wrong. Please see my posts in http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/, especially http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/&do=findComment&comment=934983 and http://www.crazyboards.org/forums/index.php?/topic/84420-2-vyvanse-doses-in-a-day-experience-over-70-mgday/&do=findComment&comment=935167. I just pick things up and put things down: http://www.uacap.org/uploads/3/2/5/0/3250432/stimulant_equivalency.pdf Link to comment Share on other sites More sharing options...
JustNuts Posted June 24, 2017 Share Posted June 24, 2017 On 6/21/2017 at 10:20 PM, Iceberg said: Regardless of the exact number I get the point...adderall might have more punch at top dose than vyvanse "Top dose" (or "maximum dose") is a very misleading term for a number of reasons. Also, you cannot actually truly directly compare mixed amphetamine salts and lisdexamphetamine in the first place due to the difference in isomers, but you can still adjust for that factor to a sufficient extent to estimate a reasonably accurate conversion between the two drugs in terms of therapeutic equivalence/effect. On 6/22/2017 at 6:11 AM, browri said: I just pick things up and put things down: http://www.uacap.org/uploads/3/2/5/0/3250432/stimulant_equivalency.pdf Read the thread/posts I linked. They specifically address that source. Here is a partial snippet: "That reference is unreliable and I believe that it is misrepresenting the conversion rate with the conversion quantity. At any rate, I cannot find any reputable literature that is in agreement with that reference's claims, so they are extremely dubious. There are of course a large number of hits from people uncritically parroting the 29.48% conversion ratio, but said hits are all from sources ranging from mildly dubious to obscenely sketchy." Note that this snippet omits my subsequent discussion on what the actual scientific literature shows, which is markedly different from that, although I do mention that no reputable scientific literature exists to support the original claim in the above snippet. Link to comment Share on other sites More sharing options...
Iceberg Posted June 24, 2017 Author Share Posted June 24, 2017 By punch I meant that Ir has a faster kick but faster crash than vyvanse or XR...I think I need that to get my ass out of bed. And yes I know the XR has an ir dose in it but it doesn't feel the same Link to comment Share on other sites More sharing options...
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