sofismos Posted April 15, 2017 Share Posted April 15, 2017 Hello. Around a week ago my Seroquel dose got increased from 150mg a day to 300mg a day. I take it for bipolar I and autism spectrum disorder. I take 150mg early in the morning, before school and the other half before going to sleep. I'm feeling extremely tired and drowsy. I find it hard to concentrate which is an issue because I have a very demanding academic life that requires me to be awake and cognitively at my peak. Since it manages my psychosis and makes me able to tolerate life I am reluctant to stop taking it. I have taken risperidone and amisulpride before but they make me extremely irritable/ don't quite stop the psychosis. In addition to Seroquel I take 20mg of escitalopram (lexapro generic). My question is, will the tiredness go away? Or do I ask for a change? Link to comment Share on other sites More sharing options...
Iceberg Posted April 15, 2017 Share Posted April 15, 2017 Possibly. Unfortunately u gotta give it a little time. Is it ir or Xr? Some people can take it all at night Link to comment Share on other sites More sharing options...
sofismos Posted April 15, 2017 Author Share Posted April 15, 2017 1 minute ago, Iceberg said: Possibly. Unfortunately u gotta give it a little time. Is it ir or Xr? Some people can take it all at night It is XR Link to comment Share on other sites More sharing options...
tryp Posted April 15, 2017 Share Posted April 15, 2017 It never fully went away for me, but it did get better to the point where I could function as a full time student (I was on 600 mg for years). Getting out of bed in the morning was always like dragging myself out of a tar pit, but I got to where I was okay during the day. Link to comment Share on other sites More sharing options...
Iceberg Posted April 15, 2017 Share Posted April 15, 2017 My doc had me take Xr all at night...sometimes less drowsiness during the day Link to comment Share on other sites More sharing options...
mcjimjam Posted April 15, 2017 Share Posted April 15, 2017 For me the tiredness went away completely. When I first took it (200mg of immediate release version, all at bedtime it knocked me right out and I needed 12 hours to sleep it off. Eventually I developed a tolerance and it had no sedative effect. When I tried taking XR (all at night) it didn't knock me out really, but spread the sedation out so I felt it some the next day. Overall many find XR to be milder sedation-wise because it releases slowly. It took quite a few months before i completely adjusted. If it works for you I'd suggest persevere if you can. Talk to your doc about possible dosing or formula change to address the fatigue. Link to comment Share on other sites More sharing options...
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