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Anyone take Benzo for Depression?


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They are even listed as such.

I've heard of people who don't want to do SSRIs use benzos instead for depression with mixed results...some it makes worse...few get better.

Seems risky to me as benzos are so sedating, but wondering if it's been successful for anyone else?

I know in the first few weeks Ativan always makes me feel better.  My depression is a very anxious one.

Edited by BrianOCD
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Benzodiazepines have a significant risk of worsening depression. I don't think I've ever heard of someone proposing to treat depression with them before. While benzos can in some cases help depression indirectly by alleviating anxiety that is interfering with your ability to handle your depression, they don't really have any direct antidepressant effects unless they're abused for the euphoric effects that they can sometimes cause when misused (not a good idea at all as benzodiazepines are both psychologically and physically addictive).

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6 hours ago, Iceberg said:

Heard of klon for depression...also heard it's a terrible idea 

It may be just me, but when I take Klonopin for more than 2-3 weeks at a time regularly (0.5-1 mg 2-3x/day), I actually get more depressed. It does wonders for my anxiety though, but I do eventually fall pretty flat.

4 hours ago, heilmania said:

My (new!) docs juuuust told me today that Klonopin is a depressant, so I shouldn't be on it, because I have depression. Makes sense to me. 

Yep. All benzos are depressants.

3 hours ago, lifequake said:

I do not find benzos to be effective for depression.  Klonopin makes it noticeably worse for me.

Same here. Except Serax (oxazepam), which I find exceedingly effective for anxiety with depression, which helps the anxiety without exacerbating my depression, regardless of how often I take it. Xanax worked well for my anxiety, but would do crazy things to my mood like make me dysphoric hypomanic or even slightly psychotic if I took it too often.

34 minutes ago, JustNuts said:

Benzodiazepines have a significant risk of worsening depression. I don't think I've ever heard of someone proposing to treat depression with them before. While benzos can in some cases help depression indirectly by alleviating anxiety that is interfering with your ability to handle your depression, they don't really have any direct antidepressant effects unless they're abused for the euphoric effects that they can sometimes cause when misused (not a good idea at all as benzodiazepines are both psychologically and physically addictive).

I think this is all the supposed "antidepressant" effect of Xanax is.

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Uggh I pretty much agree I was looking for confirmation, I was just looking for other options than SSRIs, but I guess I'm stuck with those when it comes to depressed moods.

Interesting that benzos are sometimes listed as AntiDepressants.

I stopped my ativan totally today and I do have a little more energy.

Edited by BrianOCD
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On 7/6/2017 at 11:24 PM, JustNuts said:

Benzodiazepines have a significant risk of worsening depression. I don't think I've ever heard of someone proposing to treat depression with them before. While benzos can in some cases help depression indirectly by alleviating anxiety that is interfering with your ability to handle your depression, they don't really have any direct antidepressant effects unless they're abused for the euphoric effects that they can sometimes cause when misused (not a good idea at all as benzodiazepines are both psychologically and physically addictive).

I guess it's that indirect effect that I enjoy so much.

I just typically remember my mood going high every time I take Ativan after not taking it for a while.  But I guess the elimination of the anxiety opens that up.

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On 7/8/2017 at 6:33 PM, BrianOCD said:

I was just looking for other options than SSRIs, but I guess I'm stuck with those when it comes to depressed moods.

There are other types of AD options besides SSRIs and SNRIs (Effexor is an SNRI).....such as TCAs or MAOIs, which are older drugs, but some here have had success with them.

Have you ever talked with your pdoc about trying an AD from a totally different class?

Edited by CrazyRedhead
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On 7/8/2017 at 4:33 PM, BrianOCD said:

Uggh I pretty much agree I was looking for confirmation, I was just looking for other options than SSRIs, but I guess I'm stuck with those when it comes to depressed moods.

Interesting that benzos are sometimes listed as AntiDepressants.

I stopped my ativan totally today and I do have a little more energy.

Well I refuse SSRI's. Had them in the past before being diagnosed bipolar, and they are hell to come off of, so.. nope. So instead, I take Wellbutrin which is an SNRI, and it helps a great deal!

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On 7/10/2017 at 6:38 AM, CrazyRedhead said:

There are other types of AD options besides SSRIs and SNRIs (Effexor is an SNRI).....such as TCAs or MAOIs, which are older drugs, but some here have had success with them.

Have you ever talked with your pdoc about trying an AD from a totally different class?

Not yet, he keeps pushing me to try Trintellix, that's what he wanted me to try.

Problem is I haven't felt stable enough to come off of Effexor in a few months.  

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I am dependent on xanax and it no longer has sedative effects one me, like it doesn't put me to sleep. Xanax definitely plays an anti-depressant role in my treatment because it alleviates the stress in my life that causes me to become depressed. Ever since the beginning Xanax has helped me during depressive episodes. It puts me in a better mood as well, at my prescribed doses.

Other benzos have not had this effect, such as valium and klonopin. When I was on Klonopin 1mg twice daily my mood was really low and I didn't have interest in anything. With Valium it also leaves me apathetic after daily use at higher doses (10-20mg twice daily), so I am currently sticking to 10mg nightly, sometimes not, for seizure control. My doc also wants to taper me from Xanax to a longer acting like Klonopin and Valium, but I'm not looking forward to dealing with the low mood and apathy I previously had with these two longer acting benzos. 

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  • 3 weeks later...

I've considered Ativan may help with obsessions and ruminations that go along in anxious depression.

I'm taking a small amount now to see if it will help...

Doesn't the benzo kill stress off for the most part?  That alone would be anti-depressant right?  I've been under chronic stress for the last 4 months that's led me to where I am now.

Edited by BrianOCD
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3 minutes ago, Iceberg said:

Do you think that more dose increase will help? Or is Effexor just not gonna cut it for you?

I wrote in your other post about trying TCAs

When Effexor worked, it's the best for my symptoms.

I'm just not sure it's going to be as effective this time around from what I'm going through.

I may go all the way back up to 300mg to see if I feel better though.  I'm trying to stay low on it to avoid some of the side effects, but unfortunately I'm not getting much benefit.

Edited by BrianOCD
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2 minutes ago, Iceberg said:

Yeah I've had meds no work for me the second time around after having more effect the first time 

The dosage increase should at least get some benefit back though, or does it poop out altogher?

I'm not opposed to trying TCA, are there any with low side effects?

Edited by BrianOCD
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1) for me the dose increase didn't help much...happened with geodon and latuda 

2) unfortunately, while some get low side effects, most or all have a higher side effect profile than SSRIs. Anafranil is supposedly great for OCD and its related anxiety 

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23 minutes ago, Iceberg said:

1) for me the dose increase didn't help much...happened with geodon and latuda 

2) unfortunately, while some get low side effects, most or all have a higher side effect profile than SSRIs. Anafranil is supposedly great for OCD and its related anxiety 

ugggh, well that's bad news

I'll probably try Effexor at higher dosages one more time then call it quits on it...

I guess I have a few options since I havent done that many ADs, possibly Cymbalta?  TCAs I've been looking at.  Are you on one?  And what's it like?

Edited by BrianOCD
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I'm bipolar so TCAs for me are too risky with a history of mania. They are less Rx'd now but considered just as effective according to my pdoc who says he uses them next after SSRIs. Cymbalta could be worth a look...or fetzima if SNRIs are what u wanna stick with. There's also remeron which helps some at low doses 

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4 minutes ago, Iceberg said:

I'm bipolar so TCAs for me are too risky with a history of mania. They are less Rx'd now but considered just as effective according to my pdoc who says he uses them next after SSRIs. Cymbalta could be worth a look...or fetzima if SNRIs are what u wanna stick with. There's also remeron which helps some at low doses 

If Cymbalta could work half as good as Effexor did, I'd be happy.

I'm pretty miserable atm.  Just waking up daily with constant anxiety, worries, and some depression...

So anything would help me now.

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2 hours ago, Iceberg said:

Well see how that treats you, it might be enough to make things manageable. There is also room in the dose at .5 

I don't want to overdo it though, too long on ativan generally makes me numb/depressed...

I'm dealing with an anxious depression right now.

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19 hours ago, BrianOCD said:

ugggh, well that's bad news

I'll probably try Effexor at higher dosages one more time then call it quits on it...

I guess I have a few options since I havent done that many ADs, possibly Cymbalta?  TCAs I've been looking at.  Are you on one?  And what's it like?

If Effexor doesn't work at the higher dosage you could try Pristiq (desvenlafaxine). It is very similar to effexor (venlafaxine) and might give you the relief you are looking for. Mirtazapine is another AD that isn't an SSRI or TCA, and it might be worth a try, but it is pretty sedating at lower doses, and more activating at higher doses. 

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