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Kwie

Duloxetine insomnia

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I'm new to the board.  Hi everyone.

My experience with antidepressants in the past has always been very bad.  None has ever made one iota of difference to any depression I might've had, and the side effects have been extreme.  I haven't been on any in years.

A few weeks ago, my doctor talked me into trying 20 mg duloxetine for my chronic headaches.  I was skeptical and wary, but to my amazement, it has made an enormous difference in the intensity, duration and frequency of the headaches.  It's also decreased the muscle spasms of my cervical dystonia (source of my headaches), and it has significantly elevated my mood.  I really don't want to quit, but it is causing severe insomnia.  It's been 3 weeks now, and I haven't had one full night of sleep yet.  I sleep in bursts of 15 to 30 minutes until around 3 or 4 AM, at which time I finally really sleep until about 6.  I don't think this sort of sleep is sustainable.  

 

I take the pill as soon as I wake up at 5 or 6.  I don't drink any coffee or take any sort of stimulant after about noon (no chocolate, caffeinated beverages, etc.).  I am on Adderal, but it isn't time-release, and I take it in the AM with the duloxetine.  The only other med I take is levothyrixine. 

 

I have tried melatonin and L-tryptophan, even together, and they do nothing.  I have not tried Valerian root or OTC sleep meds.

 

Any suggestions, or will this side effect eventually go away?

 

Thanks,

 

Kwie  

Edited by Kwie

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1 hour ago, Kwie said:

 Any suggestions, or will this side effect eventually go away?

I've never taken duloxetine, but insomnia is a pretty common side effect of this med, from what I have read of other's experiences.......How much Adderall are you on?.

My best advice would be to call your pdoc and tell them you're having trouble sleeping......They could probably recommend something to help you get better sleep.

Hopefully, someone with personal experience with duloxetine will reply soon and give you a better idea of what to expect going forward.

Edited by CrazyRedhead

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I am taking just 5 mg Adderal once daily first thing as soon as I wake up.  It isn't even extended or slow release.

 

Unfortunately, diphenhydramine doesn't mix well with Adderall.  It gives me a very unpleasant antsy feeling in all my limbs- what they call Restless Leg Syndrome, I think.

 

I picked up some Valerian root extract this morning.  Maybe that'll help.

 

Thanks for responding.

Edited by Kwie

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Maybe you could ask your pdoc about trying trazodone. It's an antidepressant, but it's very commonly used at low doses as a sleep aid in adjunct with antidepressants.

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I found cymbalta to be pretty energizing the couple years I was on it. Anywhere form 60-120mg but mostly at 60mg. I was on lunesta the whole time I was on it so that helped. The worst thing about cymbalta for me in regards to sleep was night sweats. Terrible night sweats. 

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