farshad040 Posted September 23, 2017 Share Posted September 23, 2017 At the moment the best one I know of is Risperidone that I know of that blocks most Serotonin receptors. Is risperidone the best one or is there a better one I dont know of? If you look at the Pharmacology of Risperdal you can see its an antagonist on many if not all serotonin receptors. Any help is appericated as I am new to this stuff myself so I dont know 100% about these stuff. https://en.wikipedia.org/wiki/Risperidone Link to comment Share on other sites More sharing options...
Iceberg Posted September 23, 2017 Share Posted September 23, 2017 Why are u looking for this? Link to comment Share on other sites More sharing options...
farshad040 Posted September 23, 2017 Author Share Posted September 23, 2017 1 minute ago, Iceberg said: Why are u looking for this? I knew someone was gonna ask .. here are a few reasons http://www.uu.se/en/media/news/article/?id=4918 https://selfhacked.com/blog/5-ht2c/ I have done tons of research on Serotonin and I have came to the conclusion that its bad especially in high amounts in the brain. You can think what you want but this is just my opinion. Just looking for a drug that can block the most serotonin in the brain. Link to comment Share on other sites More sharing options...
notloki Posted September 23, 2017 Share Posted September 23, 2017 This is foolish. Link to comment Share on other sites More sharing options...
mikl_pls Posted September 24, 2017 Share Posted September 24, 2017 Scholarly research. Link to comment Share on other sites More sharing options...
BrianOCD Posted September 24, 2017 Share Posted September 24, 2017 Don't Benzos block serotonin? They're usually used to treat Serotonin Syndrome if I'm not mistaken. But I don't if this is a good idea OP. I don't think it's about one chemical or another, but finding the right balance. Serotonin makes us feel content, don't know why you'd think it's so bad. Link to comment Share on other sites More sharing options...
farshad040 Posted September 24, 2017 Author Share Posted September 24, 2017 1 hour ago, BrianOCD said: Don't Benzos block serotonin? They're usually used to treat Serotonin Syndrome if I'm not mistaken. But I don't if this is a good idea OP. I don't think it's about one chemical or another, but finding the right balance. Serotonin makes us feel content, don't know why you'd think it's so bad. yes benzo do reduce serotonin. But I need something I can take everyday without tolerance and that makes more sense to take. Which is risperdal. Link to comment Share on other sites More sharing options...
BrianOCD Posted September 24, 2017 Share Posted September 24, 2017 (edited) Are you having anxiety issues Farshad or depression? I agree too much serotonin can make ocd and anxiety worse. It's about finding a balance, I don't think shutting down serotonin is a good idea though, it's needed for a lot of different processes. Edited September 24, 2017 by BrianOCD Link to comment Share on other sites More sharing options...
farshad040 Posted September 24, 2017 Author Share Posted September 24, 2017 (edited) 39 minutes ago, BrianOCD said: Are you having anxiety issues Farshad or depression? I agree too much serotonin can make ocd and anxiety worse. It's about finding a balance, I don't think shutting down serotonin is a good idea though, it's needed for a lot of different processes. Yes very. I have done a lot of reading and I belive I have some sort of mutation which my brain creates too much serotonin and it makes other parts of my brain run overtime . Like the amygdala, the 5ht2c receptor.. etc I belive this is the worst type of anxiety you can get. I honestly would rather have too much dopamine then serotonin. Yes I have very bad social anxiety its on another level then everyone else. My OCD is very bad too . The only thing serotonin is good for is to keep everything else balanced in the brain . But when your serotonin is soo much your other neurontransmitters go down . I only belive a tiny bit of serotonin is enough . Im my opinion it should my a lot lower than every other neurontransmitter. Well anyway anyone have any opinion on a med that blocks serotonin better than risperdal ? I see you tried zyprexa in the past it also blocks quite a few serotonin receptors. Edited September 24, 2017 by farshad040 Link to comment Share on other sites More sharing options...
mikl_pls Posted September 24, 2017 Share Posted September 24, 2017 Are you seeing a psychiatrist? 2 Link to comment Share on other sites More sharing options...
Iceberg Posted September 24, 2017 Share Posted September 24, 2017 What symptoms are you worried about? 2 Link to comment Share on other sites More sharing options...
farshad040 Posted September 25, 2017 Author Share Posted September 25, 2017 can you guys stay on topic Link to comment Share on other sites More sharing options...
jt07 Posted September 25, 2017 Share Posted September 25, 2017 There are no drugs that block all the serotonin receptors. The other posters are just trying to figure out why you think you have too much serotonin and to make sure you are under the care of a psychiatrist. It is all relevant to the topic because without context it seems like you are operating on a crackpot theory. 1 Link to comment Share on other sites More sharing options...
farshad040 Posted September 25, 2017 Author Share Posted September 25, 2017 I already told them. And if I dont wanna reveal any more info thats my choice. I didnt say all receptors I said the most. Link to comment Share on other sites More sharing options...
jt07 Posted September 25, 2017 Share Posted September 25, 2017 5 minutes ago, farshad040 said: I already told them. And if I dont wanna reveal any more info thats my choice. I didnt say all receptors I said the most. Yeah, you're right. You don't have to disclose any more info. But then people don't have to answer you either. People will just assume that you are hiding a crackpot theory rather than a theory that has been born out by peer reviewed research. Link to comment Share on other sites More sharing options...
farshad040 Posted September 25, 2017 Author Share Posted September 25, 2017 (edited) 2 minutes ago, jt07 said: Yeah, you're right. You don't have to disclose any more info. But then people don't have to answer you either. People will just assume that you are hiding a crackpot theory rather than a theory that has been born out by peer reviewed research. then remove your comment and all the other ones before that were off topic. Edited September 25, 2017 by farshad040 Link to comment Share on other sites More sharing options...
jt07 Posted September 25, 2017 Share Posted September 25, 2017 We do not delete comments on CB. And you do NOT tell us what to do. And you do not get to control what types of responses you get. Link to comment Share on other sites More sharing options...
heilmania Posted September 25, 2017 Share Posted September 25, 2017 7 hours ago, farshad040 said: then remove your comment and all the other ones before that were off topic. Hahahaha. You're kidding, right? Link to comment Share on other sites More sharing options...
tommy215 Posted September 30, 2017 Share Posted September 30, 2017 This got awkward quick... 1 Link to comment Share on other sites More sharing options...
Level_With_Me Posted September 30, 2017 Share Posted September 30, 2017 IM LIKE A BIRD i'LL ONLY FLY AWAY LOL Link to comment Share on other sites More sharing options...
notloki Posted September 30, 2017 Share Posted September 30, 2017 More like a troll. Link to comment Share on other sites More sharing options...
phidippus Posted October 15, 2017 Share Posted October 15, 2017 This is the second board farshad has posted this inquiry on. He's sold on his theory that his brain produces too much serotonin which is making his amygdala overactive. I think he has a tenuous grip on reality and is stubborn to boot. Link to comment Share on other sites More sharing options...
crtclms Posted November 2, 2017 Share Posted November 2, 2017 Farshad, some of the sources you posted in another thread to support your theory actually contradicted your theory, so how good is your research, really? And you can't just decide that you have an overload of serotonin, and then create your own treatment. Just as we cannot treat you, you can't treat yourself. You have a mental illness, how good is your judgment when you're symptomatic? If you want to suppress serotonin, which is an insane idea, go discuss your "research" with your pdoc. Hopefully you trust her or him, and will listen to them. Link to comment Share on other sites More sharing options...
San Posted November 2, 2017 Share Posted November 2, 2017 Quote I honestly would rather have too much dopamine then serotonin. You do realize antipsychotics, such as risperdal lower dopamine, right? Too much dopamine results in psychosis. Too little results in Parkinsons and such, hence the EPS side effects, and success in the past with L-dopa in some neurological disorders. (Oliver Sacks) 1 Link to comment Share on other sites More sharing options...
BrianOCD Posted November 12, 2017 Share Posted November 12, 2017 I'm actually fairly certain I'm living with little to no serotonin now as I'm in some withdrawals from Effexor. Whenever I drink caffeine I get this weird uncomfortable, dysphoric feeling that sucks. Anyways, Serotonin is that love hormone, makes you feel warm and fuzzy after doing things or interacting with people. You definitely don't want to get rid of it...reducing it or smoothing it out, many APs can do that. Link to comment Share on other sites More sharing options...
mikl_pls Posted November 13, 2017 Share Posted November 13, 2017 (edited) 19 hours ago, BrianOCD said: Anyways, Serotonin is that love hormone Oxytocin is (one of) the love hormone(s) (as well as phenylethylamine too I believe), but @BrianOCD is right, you definitely don't want to antagonize serotonin receptors just because you have a hypothesis that hasn't been validated by a psychiatrist for all we know since you didn't answer that question that your brain has "too much" serotonin. @BrianOCD, I've read about SRI's needing some serotonin to work with in order to work. Perhaps you could discuss with your pdoc supplementing with 5-HTP or taking an antipsychotic that has strong 5-HT1B/1D antagonism (which disinhibits serotonin release). Edited November 13, 2017 by mikl_pls Link to comment Share on other sites More sharing options...
BrianOCD Posted November 13, 2017 Share Posted November 13, 2017 (edited) 4 hours ago, mikl_pls said: Oxytocin is (one of) the love hormone(s) (as well as phenylethylamine too I believe), but @BrianOCD is right, you definitely don't want to antagonize serotonin receptors just because you have a hypothesis that hasn't been validated by a psychiatrist for all we know since you didn't answer that question that your brain has "too much" serotonin. @BrianOCD, I've read about SRI's needing some serotonin to work with in order to work. Perhaps you could discuss with your pdoc supplementing with 5-HTP or taking an antipsychotic that has strong 5-HT1B/1D antagonism (which disinhibits serotonin release). Ironicaly I did take a small dosage of 5-htp tonight, and I do feel better, little bit more calm. I don't know about raising it any more than 50 mgs though as it could interact with Effexor. I know you're not supposed to take it alongside ADs, but I can tell when my serotonin is dangerously low (anxious, no more vivid vision, exhausted, insomnia)...and felt it was worth the risk.... Unfortunately I've heard 5-htp wears off if you're taking it daily. Good thing is this drug is OTC so easy to get! How have you been doing mikl? Edited November 13, 2017 by BrianOCD Link to comment Share on other sites More sharing options...
mikl_pls Posted November 13, 2017 Share Posted November 13, 2017 12 hours ago, BrianOCD said: Ironicaly I did take a small dosage of 5-htp tonight, and I do feel better, little bit more calm. I don't know about raising it any more than 50 mgs though as it could interact with Effexor. I know you're not supposed to take it alongside ADs, but I can tell when my serotonin is dangerously low (anxious, no more vivid vision, exhausted, insomnia)...and felt it was worth the risk.... Unfortunately I've heard 5-htp wears off if you're taking it daily. Good thing is this drug is OTC so easy to get! How have you been doing mikl? 5-HTP is probably the best OTC supplement for increasing serotonin levels (I think it does so peripherally too, so you get some unwanted side effects, especially at higher doses) because it bypasses the rate-limiting enzyme that converts L-tryptophan to 5-HTP (if I'm not mistaken). There are other ways of increasing serotonin levels though (that I can think of off the top of my mind) but I'll PM this to you since we don't want OP to get upset about deviating from the original topic... >.> Link to comment Share on other sites More sharing options...
Persona_Is_Life Posted January 4, 2018 Share Posted January 4, 2018 You absolutely need to discuss this with a doctor. If you're worried about Serotonin Syndrome (too much) it is an emergency and will be taken seriously. Do note that there is a difference between "blocking" serotonin in terms of reuptake and in terms of production. If I remember correctly, Zofran is one med that blocks the production of serotonin whereas many psych meds block the reuptake of it. Link to comment Share on other sites More sharing options...
notloki Posted January 6, 2018 Share Posted January 6, 2018 It impossible to have no serotonin. Link to comment Share on other sites More sharing options...
BrianOCD Posted January 6, 2018 Share Posted January 6, 2018 2 hours ago, notloki said: It impossible to have no serotonin. Can you elaborate on this Notloki...I've wondered at times what a brain with zero serotonin would be like or if I ever experienced it... I think drugs like ecstacy and others can get a person close... Link to comment Share on other sites More sharing options...
browri Posted February 11, 2018 Share Posted February 11, 2018 On 1/6/2018 at 6:23 PM, BrianOCD said: Can you elaborate on this Notloki...I've wondered at times what a brain with zero serotonin would be like or if I ever experienced it... I think drugs like ecstacy and others can get a person close... Not necessarily. Ecstasy just causes extremely dramatic serotonin release, then it inhibits the reuptake to keep it all in the synapse which causes major activation of receptors (specifically pre-synaptic) which would cause a compensatory decrease in the serotonin pump. Then it upregulates MAO-A which breaks down any extracellular serotonin. So the idea that ecstasy "burns up all your serotonin" isn't too far off the mark. However, @notloki is right, a brain without serotonin would be virtually impossible, and I imagine you would probably die. Serotonin is important to regulating our body temperature, smooth muscle control like the gut, sleep rhythm. If you didn't have any serotonin I don't know if you would actually be able to sleep. Does anyone smarter than me know? Link to comment Share on other sites More sharing options...
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