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Has anyone here gotten diabetes inspidous from lithium? I had my labs drawn 2 Mondays ago and the next day the results were back already. My pdoc said I was at UNDER a therapeutic level of lithium but that my sodium levels were high enough to be diagnosed with DI. He is having me take both pills (300mg ea.) at night now, to give my kidneys a break. I pee a lot and just thought it was because of all the water I have to drink as a lithium user - but he said I could drink 1 cup of 40 and I"d pee the same amount. 

Just curious if anyone else has had this before and what they did. I am going through a rough mixed right now - need addl lithium (therapeutic dose) but can't yet because of this issue. I don't want to try anything else .... lithium is the best.

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Yes, I did. I had to stop lithium.

I was treated with a diuretic called HCTZ (name is long) which works opposite with DI. After stopping lithium and taking HCTZ my dr's did a 2 week trial off HCTZ to see if symptoms came back (stopping lithium is generally treatment, its not permanent. However, you cannot take HCTZ with lithium and the treatment is don't take lithium. At all. I have permanent damage, my eGFR  is in the 60's.)

HCTZ can cause low potassium so I took 'behind the counter' (not Rx,  but not out in the open) potassium calculated by your blood work reading. After 2 weeks off HCTZ I was fine.

The big problem with DI is that you pee protein. That's how I was dx'd. That is not good.

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