JustGotOut Posted June 14, 2018 Share Posted June 14, 2018 (edited) I am on 20 mg latuda 2 mg klonopin 10 mg ambien 200 mg trazodone and i also take 50 mg of benadryl each night. Which of these cause problems ejaculating? and what are replacements in their class of medications that dont cause ejaculation problems? I have no problem ejaculating when i watch porn and masturbate. But I finally had sex and i was able to maintain an erection but my penis was so numb i didnt even know my penis was erect and i didnt even feel the vagina i was in. It felt like something was around my penis but it was very little sensation and this girl i was with was very tight but i still felt nothing. Even when she touched my penis i felt barely anything like it wasnt there. Also i wasn't able to ejaculate even though she stimulated my penis for hours. My erection was stable all throughout the sex but it was never 100% erect but maintained about 65-70% erection for a few hours before we decided to stop. Edited June 14, 2018 by JustGotOut Link to comment Share on other sites More sharing options...
CrazyRedhead Posted June 14, 2018 Share Posted June 14, 2018 (edited) I'm just making a guess, but the problem you describe could be a side effect of either latuda or trazodone...... I would suggest letting your doc know about it, and see what they recommend. Edited June 14, 2018 by CrazyRedhead 1 Link to comment Share on other sites More sharing options...
RisingRayne Posted June 14, 2018 Share Posted June 14, 2018 It's likely the Latuda or trazodone. Serotonin from the trazodone complicates sex for sure (delays climax and possibly causes insensitivity). You are on the antidepressant level dose of trazodone (lower dose than that are used for primarily for insomnia). Trazodone is also know to cause priapism, an involuntary erection that can last for too long and may be painful. Just FYI in case that occurs. Seek emergency attention if it lasts 4 hours (heck personally I would go earlier for help). Latuda can affect your prolactin levels, one of your sex hormones. Too high of levels can you can develop breast tissue. Your doctor may occasionally do blood work to check your levels. Do not worry, high levels would be detected before breast development occurs. SSRI induced sexual dysfunction can sometimes be improved with the addition of Wellbutrin (buproprion). If you are interested, I would consult your provider to see if it is appropriate. There are couple other options, example, switching to another SSRI like Remeron (mirtazepine). It has low incidence of sexual dysfunction and also helps with sleep. The only downside is that it can cause weight gain in some individuals. I wish you the best of luck! It takes some time to get on the right medications. If it interferes with your relationship or is frustrating, definitely discuss this with your provider. V/R, RR Link to comment Share on other sites More sharing options...
JustGotOut Posted June 14, 2018 Author Share Posted June 14, 2018 (edited) So the benzos i'm taking aren't likely to effect sexual function? Edited June 14, 2018 by JustGotOut Link to comment Share on other sites More sharing options...
CrazyRedhead Posted June 14, 2018 Share Posted June 14, 2018 (edited) 1 hour ago, JustGotOut said: So the benzos i'm taking aren't likely to effect sexual function? It is possible for Klonopin to cause sexual problems.........But I could find no reports at all of Ambien causing it. Edited June 14, 2018 by CrazyRedhead Link to comment Share on other sites More sharing options...
Iceberg Posted June 14, 2018 Share Posted June 14, 2018 Ejaculation d/o is actually listed as a traz side effect on medscape. Also found some reports that it can be used to treat premature ejaculation which would mean it could be causing or conspiring to cause your problem Link to comment Share on other sites More sharing options...
mikl_pls Posted June 14, 2018 Share Posted June 14, 2018 Trazodone actually can enhance sexual function due to the 5-HT2A antagonism and, in higher doses, 5-HT2C antagonism. It can cause priapism in both sexes, and It can actually cause spontaneous orgasm in women. I don't think it's trazodone. But then again, this source mentions that trazodone can cause ejaculatory inhibition that can be resolved from discontinuing trazodone: https://www.ncbi.nlm.nih.gov/pubmed/17454520 1 hour ago, JustGotOut said: So the benzos i'm taking aren't likely to effect sexual function? It's possible that it could be the clonazepam too, however. https://www.ncbi.nlm.nih.gov/pubmed/9160580 Quote This retrospective study examined the records of 100 male veterans with post-traumatic stress disorder (PTSD) selected in alphabetical order from an active treatment file of 230 patients. Forty-two patients had received clonazepam (mean maximum dose: 3.4 +/- 1.6 mg/day) at some point during their treatment. Of these, 18 (42.9%) complained of significant sexual dysfunction (primarily erectile dysfunction). Eighty-four patients received diazepam (mean maximum dose: 52.1 +/- 29.7 mg/day), nine received alprazolam (mean maximum dose: 5.2 +/- 2.8 mg/day) and eight received lorazepam (mean maximum dose: 3.8 +/- 2.4 mg/day). None of these patients complained of sexual dysfunction during treatment with these three other benzodiazepines. Our findings suggest that benzodiazepines, particularly clonazepam in the current study, can be a cause of sexual dysfunction in many male patients. They didn't mention ejaculatory dysfunction, but it may have been a problem in the patients since it mentioned "sexual dysfunction" in general. I doubt it could be the Latuda at 20 mg. Link to comment Share on other sites More sharing options...
Iceberg Posted June 14, 2018 Share Posted June 14, 2018 What are u taking the traz for ? Link to comment Share on other sites More sharing options...
JustGotOut Posted June 14, 2018 Author Share Posted June 14, 2018 Just now, Iceberg said: What are u taking the traz for ? Sleep. Link to comment Share on other sites More sharing options...
Iceberg Posted June 14, 2018 Share Posted June 14, 2018 Maybe ur pdoc could work with you to come up with another sleep strategy...although as mikl_pls suggested it's tough to nail down one culprit. Have you tried many other things for sleep? Link to comment Share on other sites More sharing options...
JustGotOut Posted June 14, 2018 Author Share Posted June 14, 2018 1 minute ago, Iceberg said: Maybe ur pdoc could work with you to come up with another sleep strategy...although as mikl_pls suggested it's tough to nail down one culprit. Have you tried many other things for sleep? I started this combo to avoid weight gain. I've found a way to get my weight under control through a ketogenic diet. So a med that causes weight gain as a side effect isn't a problem. So is remeron a good option? I thought it was an antidepressant too? Link to comment Share on other sites More sharing options...
CrazyRedhead Posted June 14, 2018 Share Posted June 14, 2018 2 minutes ago, Iceberg said: Have you tried many other things for sleep? He mentioned he's taking Ambien 10mg.......I assume that's for sleep, too...... 2 minutes ago, JustGotOut said: I started this combo to avoid weight gain. I've found a way to get my weight under control through a ketogenic diet. So a med that causes weight gain as a side effect isn't a problem. So is remeron a good option? I thought it was an antidepressant too? Yes, Remeron is an antidepressant.......For sleep, it works better at lower doses. Link to comment Share on other sites More sharing options...
jt07 Posted June 14, 2018 Share Posted June 14, 2018 Remeron is a weight gainer, but if you are ok with that, I found that it had no sexual side effects. Link to comment Share on other sites More sharing options...
JustGotOut Posted June 14, 2018 Author Share Posted June 14, 2018 Remeron doesn't effect serotonin? or why doesnt it cause sexual side effects? Link to comment Share on other sites More sharing options...
Iceberg Posted June 14, 2018 Share Posted June 14, 2018 4 minutes ago, CrazyRedhead said: He mentioned he's taking Ambien 10mg.......I assume that's for sleep, too...... Sorry totally missed that...up way to late last night. @JustGotOut it is an ad that affects serotonin but it works differently than trazodone (remeron is a tetracyclic while trazodone is a SARI) . It is a good option but if your current cocktail is working your pdoc may not want to rock the boat too much Link to comment Share on other sites More sharing options...
jt07 Posted June 14, 2018 Share Posted June 14, 2018 7 minutes ago, JustGotOut said: Remeron doesn't effect serotonin? or why doesnt it cause sexual side effects? Yes, it definitely affects serotonin, but as Iceberg said, it has a different mechanism of action. It also affects norepinephrine. Link to comment Share on other sites More sharing options...
l'appel du vide Posted June 14, 2018 Share Posted June 14, 2018 I am 99% positive that it is the Latuda causing your problems. Despite what many are saying here, Trazodone actually makes me horny, though I am on 100mg compared to your 200mg. Link to comment Share on other sites More sharing options...
argh Posted June 14, 2018 Share Posted June 14, 2018 57 minutes ago, JustGotOut said: Remeron doesn't effect serotonin? or why doesnt it cause sexual side effects? It does affect serotonin, via antagonism/inverse agonism of the 5HT2 and 5HT3 receptors. SSRIs, which have the notoriety of causing sexual side-effects, are reuptake inhibitors. Link to comment Share on other sites More sharing options...
JustGotOut Posted June 14, 2018 Author Share Posted June 14, 2018 25 minutes ago, argh said: It does affect serotonin, via antagonism/inverse agonism of the 5HT2 and 5HT3 receptors. SSRIs, which have the notoriety of causing sexual side-effects, are reuptake inhibitors. So remeron decreases serotonin and ssris increase them? Link to comment Share on other sites More sharing options...
Iceberg Posted June 14, 2018 Share Posted June 14, 2018 No, remeron doesn't decrease it, just has a different method of managing it...remeron also hits norepinephrine which can give a boost Link to comment Share on other sites More sharing options...
JustGotOut Posted June 15, 2018 Author Share Posted June 15, 2018 I'm more stable now than ever. I am wondering if you guys think that it would be best to try to see if this problem goes away through avoiding porn and masturbation before tinkering with medications. Because I"ve been a heavy porn user for the last 16 years and watch some very explicit stuff. I also masturbate with a death grip. So I honestly don't know if its the meds or the porn and masturbation style. Link to comment Share on other sites More sharing options...
argh Posted June 15, 2018 Share Posted June 15, 2018 Cut back and see what happens. Maintaining stability is harder than not pawing at yourself as much. Maybe. Link to comment Share on other sites More sharing options...
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