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Hey guys.

I’ve been pretty stable on Depakote, but it sure does come with some undesirable side effects. Somehow it makes me feel overwhelmed. It’s kind of a brain fog 2.0 feeling. Also it haven’t helped much with my anxiety, and there’s still some depression left too. 

I’m also on 2 antidepressants and a small dose of gabapentin, with no luck.

What are your experiences with lithium or seroquel? I do not want to feel like a zombie and also do not want to feel too flat or foggy

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I'll let others comment on lithium and Seroquel. I'll just say that Tegretol is another alternative to Depakote. I'm not bipolar but Tegretol is the glue that holds my brain together. It also keeps me from becoming suicidally depressed. It doesn't give me brain fog either at my dosage. I find it weight neutral also.

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1 hour ago, jt07 said:

I'll let others comment on lithium and Seroquel. I'll just say that Tegretol is another alternative to Depakote. I'm not bipolar but Tegretol is the glue that holds my brain together. It also keeps me from becoming suicidally depressed. It doesn't give me brain fog either at my dosage. I find it weight neutral also.

Thank you! Haven’t tried tegretol yet. Tried trileptal though, which is supposed to be similar. It made me very depressed... I have tried lamotrigine, abilify, trileptal, gabapentin, lyrica and valproate/depakote already. 

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I've been taking lithium for over 10 years and it eliminates my suicidal thoughts.

From it I got thyroid problems and feel like I need to drink water every 15 minutes. 

 

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Lithium, at least try it and see if it suits you. I gather from your username you have cycling problems. Depakote is the go to drug for that and rapid cycling, so keep the fact that you are replacing something that controls cycles really well and try to replace it with the same. I would choose Lithium over AP's/AAP's, it has a better safety profile. There are no occult problems that don't reveal themselves until they have been doing irreversible damage. With Lithium you can test and see problems (kidney, thyroid) coming but before they have not done permanent damage yet.

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13 minutes ago, notloki said:

Lithium, at least try it and see if it suits you. I gather from your username you have cycling problems. Depakote is the go to drug for that and rapid cycling, so keep the fact that you are replacing something that controls cycles really well and try to replace it with the same. I would choose Lithium over AP's/AAP's, it has a better safety profile. There are no occult problems that don't reveal themselves until they have been doing irreversible damage. With Lithium you can test and see problems (kidney, thyroid) coming but before they have not done permanent damage yet.

Yeah, those occult problems are the worst. That's why I keep a bottle of holy water on my nightstand.

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1 minute ago, jt07 said:

Yeah, those occult problems are the worst. That's why I keep a bottle of holy water on my nightstand.

 

Occult is a medical term for "hidden".

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1 hour ago, notloki said:

 

Occult is a medical term for "hidden".

I stand corrected, but I'm still keeping the holy water on my nightstand.

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13 hours ago, notloki said:

Lithium, at least try it and see if it suits you. I gather from your username you have cycling problems. Depakote is the go to drug for that and rapid cycling, so keep the fact that you are replacing something that controls cycles really well and try to replace it with the same. I would choose Lithium over AP's/AAP's, it has a better safety profile. There are no occult problems that don't reveal themselves until they have been doing irreversible damage. With Lithium you can test and see problems (kidney, thyroid) coming but before they have not done permanent damage yet.

That actually makes a lot of sense! Thank you so much. Does it give you emotional numbness? 

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It can but it's not a sedation bomb like seroquel. I don't typically have to much of an issue, seroquel was numbing as all hell, but some people do get emotional blunting to various degrees 

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