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mikl_pls

"Pseudo-drug holiday?" Alternating dosages of Dexedrine?

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I somehow ran out of Dexedrine before my next prescription was labeled to be able to be filled this past weekend... Don't know how. I never abuse my stimulants. I take them as prescribed, religiously and meticulously, dispensed in my pill planner every week. I have heretofore never taken "drug holidays" though. So anyway, this forced me to take a one-day drug holiday from my usual 60 mg/day Dexedrine, and I can say that it was absolutely dreadful. 

I'm taking it mainly for ADHD-PI, but also for treatment resistant bipolar depression and hypersomnia unspecified, as well as to assist with weight loss. Just one day without, and I slept practically all day, and when I wasn't asleep, I was either a weeping, ugly-crying mess, or I was binge eating. I gained 3 lb the next day, which I know isn't a whole bunch, but, you know... I'm pretty sensitive about weight gain.

I filled my Dexedrine a day later than the day was indicated so as to not look like I was "looking for a fix..." especially since I'm trying to get a job at the pharmacy at which I fill my prescriptions, start back on my Dexedrine, and two days later (today), I am feeling better than I've felt in about in month or so (before I switched to Rexulti and ruined everything good I had going for me). I felt like I did right when I switched from 40 mg to 60 mg, my mood was shining and gleaming, I was talkative and laughing, I wanted to do things and wanted to go out of the house, I didn't want to eat everything in sight. TL;DR: I was back to my normal self +1.

My question is, would there be some advantage to taking some sort of "pseudo-drug holiday" wherein I sort of alternate between 30 mg and 60 mg each day, or take 30 mg on the weekends and 60 mg during the week days or something like that? Or no? Has anyone tried this sort of regimen? I don't want to NOT take my Dexedrine, that was pretty damn terrible the day I went without it. I guess it does show how dependent I am on it though... :( But any input would be appreciated.

Edited by mikl_pls
Left out a small phrase within a sentence

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I kno it works for some people. I kno people at my school who take less on non class days or back off during vacations 

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I think you need to remain on enough for your stim to be functionable. Totally not taking your med, with your symptoms crashing back or you experiencing fatigue and depression every other day or all weekend is torture to me.

I find that the amount of amphetamine I need varies day to day so my pdoc has given me the OK to dose as I like, the directions on the bottle (30 mg tabs) say "Take 3 tablets every day" so I am free to take up to 90 mg a day. I can take all of it (90 mg) at once though those days are few. Sometimes I take 60 mg in the morning because I just can't wake up and on those days and other days where I know I will be busy later in the day I tailor my dosing to match that. I find that this flexible dosing results in taking less amphetamine, and therefore having less tolerance. 

My doctor says he is comfortable raising my dose until I get psychotic and then we will know how much is too much.

Edited by notloki
added "My doctor says......."
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16 hours ago, notloki said:

I think you need to remain on enough for your stim to be functionable. Totally not taking your med, with your symptoms crashing back or you experiencing fatigue and depression every other day or all weekend is torture to me.

I find that the amount of amphetamine I need varies day to day so my pdoc has given me the OK to dose as I like, the directions on the bottle (30 mg tabs) say "Take 3 tablets every day" so I am free to take up to 90 mg a day. I can take all of it (90 mg) at once though those days are few. Sometimes I take 60 mg in the morning because I just can't wake up and on those days and other days where I know I will be busy later in the day I tailor my dosing to match that. I find that this flexible dosing results in taking less amphetamine, and therefore having less tolerance. 

My doctor says he is comfortable raising my dose until I get psychotic and then we will know how much is too much.

I see... Sounds like your pdoc knows how to prescribe stimulants. Much more so than mine...

I think my pdoc is way, way, way concerned about the cardiovascular side effects of stimulants, which is why she just stopped prescribing me stimulants altogether, and why she is now restricting my antidepressant doses (yeah... yet she's pushing my antipsychotic dose).

So as I've said before, I have had to go to my NP for my stimulant. I think my gdoc has physician burnout because he literally brushes me away for anything psychiatric. I'm not the only one whose said that either.

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