Simba Cub Posted September 30, 2018 Share Posted September 30, 2018 Clozapine is often known as the "dirty drug" and the "chemical kosch". So why does it have to be, more often than not, the most effective antipsychotic out there? The thing is so atypical it's not even classed as "atypical"! Quote Link to comment Share on other sites More sharing options...
looking for answers Posted September 30, 2018 Share Posted September 30, 2018 2 minutes ago, Simba Cub said: Clozapine is often known as the "dirty drug" and the "chemical kosch". So why does it have to be, more often than not, the most effective antipsychotic out there? The thing is so atypical it's not even classed as "atypical"! side effects? Quote Link to comment Share on other sites More sharing options...
netsavy006 Posted September 30, 2018 Share Posted September 30, 2018 I don't know the specifics but I think it works differently in the brain compared to other antipsychotics. Quote Link to comment Share on other sites More sharing options...
CrazyRedhead Posted September 30, 2018 Share Posted September 30, 2018 (edited) 1 hour ago, looking for answers said: side effects? ^This^, IMO.......Clozapine has a very long list of potential side effects: https://www.webmd.com/drugs/2/drug-5194/clozaril-oral/details/list-sideeffects Edited September 30, 2018 by CrazyRedhead 1 Quote Link to comment Share on other sites More sharing options...
Wonderful.Cheese Posted September 30, 2018 Share Posted September 30, 2018 @Simba Cub I don't want to be taking this in the first place. This is a last ditch effort for me. Like the last chance I've got. Im just starting it. I've literally tried every AAP besides rexulti and vraylar and I've tried a typical AP as well. My pdoc talked me into this. Maybe I should just quit it now before something bad happens side effect wise. My blood count has gone down already, although still in the acceptable range. Am I doomed? Quote Link to comment Share on other sites More sharing options...
gb84 Posted September 30, 2018 Share Posted September 30, 2018 (edited) 12 minutes ago, Wonderful.Cheese said: @Simba Cub I don't want to be taking this in the first place. This is a last ditch effort for me. Like the last chance I've got. Im just starting it. I've literally tried every AAP besides rexulti and vraylar and I've tried a typical AP as well. My pdoc talked me into this. Maybe I should just quit it now before something bad happens side effect wise. My blood count has gone down already, although still in the acceptable range. Am I doomed? You're not doomed. Just make sure you keep getting your blood tests. If your prescription is ready for you then you are In the clear and can relax a little . My white cells fluctuated as well from time to time. But I can say that every time I went up in dosage I felt so much better. I hope you experience the same feeling. Try to be patient, I know it is tough. Edited September 30, 2018 by gb84 1 1 Quote Link to comment Share on other sites More sharing options...
Simba Cub Posted October 1, 2018 Author Share Posted October 1, 2018 With Clozapine, you need regular blood tests to prevent a fatal side effect. It's also guilty often of playing dickey with your heart, liver and lungs. Not so great. But by gum, it WORKS. Quote Link to comment Share on other sites More sharing options...
CeremonyNewOrder Posted October 1, 2018 Share Posted October 1, 2018 (edited) My current pdoc says it is the hassle of the blood tests that make clozapine not a first line med. Personally, I'm starting to think it is under prescribed. I feel like if you truly have schizophrenia/schizoaffective disorder and have failed on two or three anti-psyhotics then it's time to try clozapine. It is the gold standard for psychosis and it has some sucky side effects but it works and it is less sucky than say Haldol. Anti-psychotics have improved. I'm also curious why clozapine hasn't been tried more with treatment resistant bipolar 1 as pdocs often use other anti-psychotics to treat their symptoms. Edited October 1, 2018 by CeremonyNewOrder Quote Link to comment Share on other sites More sharing options...
Iceberg Posted October 2, 2018 Share Posted October 2, 2018 21 hours ago, CeremonyNewOrder said: My current pdoc says it is the hassle of the blood tests that make clozapine not a first line med. Personally, I'm starting to think it is under prescribed. I feel like if you truly have schizophrenia/schizoaffective disorder and have failed on two or three anti-psyhotics then it's time to try clozapine. It is the gold standard for psychosis and it has some sucky side effects but it works and it is less sucky than say Haldol. Anti-psychotics have improved. I'm also curious why clozapine hasn't been tried more with treatment resistant bipolar 1 as pdocs often use other anti-psychotics to treat their symptoms. According to a few doc's including my pdoc and one of my ketamine doc's... It's coming back into fashion a bit for BP1 Quote Link to comment Share on other sites More sharing options...
Simba Cub Posted October 2, 2018 Author Share Posted October 2, 2018 If you wanted under used meds, look no further than MAOIs. Yes, they carry a strict diet and no-OTC meds, to name a few problems, but as any older psychiatrist will tell you, they damn well work! Quote Link to comment Share on other sites More sharing options...
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