Have any of you had or have read of gabapentin being of use as an adjunctive therapy for people with treatment resistant depression/anxiety/bipolar?
I have been doing research and some sources say it helps, others say there is no strong clinical proof. I think a lot of the conflicting reports I have seen has to do with it simply not being studied en mass.
Any advice/experiences regarding this? If so, what was your dosing?
I welcome you to rate all the psychotropic drugs which you took in the past or are taking in the present. A short explanation of your experience with the drug(s) would be helpful, so that we better understand your rating.
Oh, and please tell us which conditions you treat(ed). Thanks.
Rating Scale is from 0 to 5... "zero" being the worst, "five" being the best.
Sertraline 2 / 5 - subtle effects. Did help with psychosomatic ailments, derealization and cognition, but caused SSRI-typical apathy & indifference. Not sure if it did anything for my social anxiety and psychomotor agitation. At most minor effects. I did take it for two years.
Mirtazapine 2 / 5 - elephant tranquilizer. Didn't like the severe sedation. Didn't sleep well on it, bad dreams. Caused RLS. Was good for appetite, weight gain and IBS. I was on it for two weeks.
Promethazine Syrup / Drops 20mg / ml | 3 / 5 - I rather liked that one. At a lowish dose (15 drops or so) it has a nice calming effect on me, without sedating me too much. Lowers anxiety and agitated states. Brings order into chaos. Good for appetite and stomach. I take it occasionally.
N-acetylcysteine (NAC) 2.5 / 5 - Is a good supplement. Heightened focus, less derealization, world seems more colorful. Interesting stuff. Definitely worth a try.
Conditions treated: Anxiety, depressive states, psychomotor agitation, somatization disorder.
It's a thing! Allergan submitted data from 3 trials. Two demonstrated that 1.5mg was superior to placebo in treating bipolar depression, and the other study demonstrated that both 1.5mg and 3mg were capable doses. Therefore, the acute manic/mixed indication and dosing will remain the same with an initial dose of 1.5mg and recommended dose range of 3-6mg. Whereas bipolar depression will be a starting dose of 1.5mg with a recommended range of 1.5-3mg.
This is a big step because now cariprazine joins both quetiapine and lurasidone as being the only 3 medications approved to treat bipolar depression specifically. Lamotrigine is often used but it's only approved to delay the time between episodes (manic/mixed or depressed).
I've recently started taking Latuda again, which is one of the few meds that has helped me to feel better in the past. Unfortunately, it makes my entire body sweat like crazy. Last summer I was dripping with sweat, showering a couple of times a day and changing clothes multiple times. Trying to blow dry my hair after I've gotten out of the shower is a joke, and on the rare occasions I try to apply makeup I blast a fan on my face to try to keep it from dripping right off without much success. I've taken Clonidine and Oxybutynin in the past, both of which can treat excessive sweating, without any luck. I'm also currently on a low dose of Propranolol. The sweating is definitely a result of the Latuda and not a hormonal problem. I have an appointment to see a rheumatologist in a couple of weeks about this, but wondered if anyone here on CB had had success treating excessive sweating. I've found it helps for me to go into these types of appointments with as much information as I can gather. Thanks in advance for your help.
Latuda has gone generic, but it's not available in pharmacies yet. Does anyone have any idea when it will be available in pharmacies?
I'm seriously considering switching to it when I see my pdoc either 2 weeks from now, or, if I can, bump up my appointment to next week, and if it will be available in pharmacies by then, I'd like to be prescribed Latuda. But if it's still brand-name only by then, I can't afford the $636 copay even with the even with the copay coupon which only covers up to only a certain amount.