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Effexor and Seroquel for anxiety and sleep?


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I'm not sure where to post this but just wondering what you guys think about this combination. I suffer from extreme anxiety, panic attacks, depression, and right now lack of sleep. The doctor prescribed Temazapam for sleep instead of klonopin and i was awake the ENTIRE night. My eyes felt tired, however my brain would not shut off and i couldn't fall asleep.  Last time we tried adding seroquel to Lexepro and the seroquel made me sleep! I will literally knock out at 12.5MG.  I still have it at home and am wondering if it's safe to take with Effexor. I'm desperate for sleep, and have left a message with my doctor, but who knows when she'll get back to me. Any thoughts? Even if i could take it for a night or two. Does anyone take this combination?  I just upped my effexor does to 225 6 days ago, so that could be the reason for insominia.

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If your Effexor dosage is high enough to hit the noradrenaline transporter and you are not yet adjusted to that it may cause insomnia.

Adding Seroquel to Effexor is common, as are other ssri/snri+antipsychotic combinations.

The being said, I wouldn't recommend taking an antipsychotic med without my pdoc's recommendation.

Other than that, is Effexor an effective antidepressant for you?

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Thanks guys! I heard back from my doctor. She said i could take half or one 25MG tablet. I took 12.5MG and knocked out for 10 hours. It was the BEST sleep ever. I don't think the effexor is working as it should. I see to be more anxious on the higher dose. It's only been a week, so I will give it some time. I also take 2MG of klonopin daily. I really need something that works for anxiety. 

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  • 5 weeks later...

I think I may try gabapentin. I tried it once for a few days and it made me shaky so I stopped. Did it do that to you?  seroquel 50xr is not working out for me. It’s does not sedate or calm me down at all, only the IR at 12.5 for sleep I’m so scared of taking anymore seroquel. The xr version made my resting heart rate higher and that freaked me out. I’m scared of getting diabetes or having a heart problem from it.

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  • 3 weeks later...

So just to update- I restarted the seroquel 50MG xr two weeks ago. The first week, i was sleepy and pretty calm. I find that is helping a bit for my anxiety and definitely for my sleep. Unfortunately, i have bad dreams on this med, but i'm willing to stick with it if it actually works. Does anyone know what dose helps anxiety? does it actually take 3-4 weeks like my doctor is saying. Just curious if i'm better off trying something else.

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