Doctor has me on
200mg Lamictal [100mg bid]
750 mg Depakote [250mg tid]
When I when to the pharmacy, they said there was a RED ALERT. I know that Depakote decreases the clearance of Lamictal, my question is by how much? Anyone know? Does the dosage of Depakote matter? Like if I went to 1000mg of Depakote would that increase my Lamictal level even more?
Forgot to take Lamictal yesterday (I took my other meds). Holy Hell, I took my dose today (on schedule) and I STILL feel awful!! I've only been on 100mg....I thought Lamictal had a super-long half-life? Yesterday went like this:
10am - up, had breakfast
11am – slight Brain “swishes” started (was out the entire day)
12pm – Stronger Brain zaps start
1:30pm – Lunch (meat, salad/veg)
2:30pm – Sudden extreme exhaustion
4pm - more brain zaps => ZAP ZAP ZAP! 🤯
7pm - Irritability starts
11pm – Tea, bedtime, could not fall asleep (I haven't had insomnia in 2+ years)
...Night sweats…Restless legs.....
12am – Ruminations, feel weepy
..Insomnia ensues…(Toss & turn, sweaty/achey all night)
It's now 12pm,and I am STILL having brain zaps! I worry I’ll never be able ever taper, switch from, or withdraw from this med. You probably think well, with MI, WHY would you ever go off it? For me, longterm, these meds are band-aids. There is always a price. Ok, maybe great at preventing acute/severe depression, but as a result, they rob me of any spark, joy, elation, happiness, libido, sexual sensation/response, feelings of reward, love.... This disturbs me. I used to know what positive emotions felt like…
So I’m stable, existing.....but still lacking will or any interest in living....
Is it safe to take regular Quetiapine 800mg all at night? Pdoc prescribed four 200mg tablets at night, but maximum single dose is 400mg. If I want decent sleep I have to take all dose (800mg) as a single dose at night. I'm feeling fine, no overdose symptoms, just little concerns about safety.
For the last three months I have been lowering my Seroquel dose. Well longer than that. Due to long term use I developed cataracts and my cholesterol is very high.
Over about a year I dropped from 700 to 400mg. Easy peasy.
This last 400 has been awful. I am going slowly. I get so sick. Sweats, headaches, can’t eat, can’t sleep. Like no sleep. So I get to none. Made it. Doing well. Two weeks out things are not good at all.
I cant even explain how my head is acting. Not good on the mood spectrum (BP 1) I moved back to 50mg. (Pdoc is on board) I can sorta sleep and other physical symptoms minimized.
I am rapid cycling and I am sure I am not hiding it well at work.
Looking for some insight into others experiences.
Did you get off successfully?
How long till negative symptoms were gone?
Did you have to change to another AP?
Thanks for any shared experiences in advance .