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Medication for Treating OCD


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It seems that one of the more popular medication combinations for treating OCD today is Paxil or Luvox augmented with Seroquel.

I am wondering, has anyone out there tried Prozac + Abilify in order to achieve similar effects?

Any experiences with prozac and/or abilify for OCD, Panic Disorder, Depression or Psychosis would be appreciated.

I personally am on the Paxil/Seroquel combo, but am interested in alternatives. 

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I was on luvox, but it gave me double vision and I went off it (doctor's orders).  The abilify seems to be aking care of my compulsive thoughts, but I am also taking lex, wb, and now effexor.

Tommy

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Doesn't sound good VE.

Have you ever been on paxil and if so how was it for you?

I think from memory you are on lexapro now?

Cymbalta (60 mgs) and Seroquel (100 mgs) are the two that are helping with anxiety / OCD stuff.

Cymbalta hey.  Its not a popular med here in australia.  I think its considered where effexor doesnt work well.

Do you find seroquel is effective at that dose?  Im taking 1500mg/day at the moment.  I found it started kicking in at 600mg, but wasnt truly effective until 900mg.  Upping the dose has just made it more effective for me, and cut my valium usage right down.  Mind you I have a slightly different condition to you....

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The seroquel is fairly effective there.  I have to do a balencing act with my ADD meds and APs.  At doses where APs really work well for anxiety they totaly negate the effect of the stimulants.  I absolutely can't take stimulants without some kind of AP to buffer the increased obsessions they cause.  Meds going in circles.  Yay.

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i have minimal experience with abilify and prozac, but from the little experience i had with prozac i didn't find it helped my ocd anymore than the other ssri's i've tried.  abilify i tried for one night, couldn't sleep - just restless and keyed up the whole night, and then nauseous the next day - so i didn't need another night of that to say no fricking way. 

prozac was the last ssri i tried.  the first week i was on it - barring a few days where it seemed to plunge me into more depression - i actually felt really good for once.  could have been a factor of a lot of different things though - being out of town in the summer, and actually doing stuff i enjoy.  it also seemed to raise my blood sugar at first (i'm type 1 diabetic).  but for about two weeks things seemed really good on it (i speculate that it was also the antibiotic i was on at the same time, but i guess that's a different thread).  then it seemed to plunge me into the usual ssri-start up roller coaster.  well more of like the roller coaster that just drop you 60 feet without any warning - leaving you sore for awhile.  not that it was really dramatic or anything, just the same kind of depression i had experienced when i tried lexapro earlier that year.  eventually i felt 'alright' - and actually felt pretty good at times five or six weeks into it.  but that could also have been because i had a job temporarily.

i think i might have started up to 40 mgs around this time, but i think i was still at 20.  when the job ended (it was just a temp assignment) i went through the week from hell.  just couldn't distract myself, felt my anxiety steadily rising, kinda going out of mind.  culminating in me breaking three family picture frames and cowering in the bathtub one day a week and a half later (could have been the assault of just getting cable tv and hating what i was watching too)  - NOT a fun time.  so i stopped the prozac, and things seemed to calm down a bit.  its been almost seven months since then - and i haven't got my problems figured out much better, but i don't have the AD distracting me from realizing what they are either.  i seriously hesitate going back on an ssri again - not because of the prozac thing, for other reasons.  but i think the prozac - by working on norepinephrine too slightly (my pdoc at the time called it a 'dirty drug' - really fucked me up.  i really wish the initial feeling i had on it stayed - or i could have figured out the combination and dosage to stay feeling that way, cause i ALMOST felt normal there for awhile.  but ultimately i think it was just a painful trial to realize that i can't mess with my norepinephrine at all without experiencing some consequences.

SO. . . the point of all that stuff you probably didn't read is: i would say prozac and abilfy would be a pretty horrible combination for ocd/anxiety.  1500mg is a ton of seroquel, is there any way you could cut back on that - or look at other ways to cut down your anxiety?  jumping from all that paxil and seroquel to the prozac and abilify sounds like it would just flip your whole world upside down - and exhange too much downer effect, for too much stimulant effect.  but who knows - i just certainly wouldn't want to try both of those drugs at the same time. 

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Chimpy: Risperdal and Zyprexa both helped with my OCD as did Geodon albeit to a lesser degree.  I prefer Seroquel because it seems to have the best side effect / benifit ratio for me but I'm not sure that such would be the case with the kind of dose you are on.  The main symptom I'm concerned with controling is the intrusive thoughts as they are what seem to trigger everything else.  I don't have major compulsions other than some hording. 

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  • 3 weeks later...

A quick update, after three deep sessions of psychotherapy my psychiatrist has changed my dx to schizophrenia.  Its upsetting in some ways but a relief in others.  Its good to know what is causing the symptoms and what needs to be treated. I now have 1 dx instead of 4. 

He has already changed me over this week from paxil to prozac - the change was really smooth.  We meet again in four weeks and he is going to try changing me from seroquel to abilifym or to a combo of both. 

I dont have the catotonic or paranoid type so you can rest assure that my posts over the years have had some legitimacy and are primarily based on fact and rationale.  How much else of my life is so remains to be seen. ;)

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chipmaster-

my pdoc (actually pnurse) doesn't know if i'm bp1/psychotic or schizoaffective, but i think i can contribute in the ssri/AAP department. I've been on all the ssri and aap drugs.

i like paxil, but it made me manic and compulsive. after some trial and error, lex seems to be my best bet. prozac was too weak. my best friend, who has aspergers, loves prozac (he also has a medical condition that is treated with prozac). my experiences with the aap drugs leave me wondering if they are worth it- FOR ME. clearly, for a schizophrenic person, they are essential. if you'd like to try abilify, i'd say go for it. even combo-ing with Seroquel wouldn't be too bad I don't think, unless they work on the same thing, and that i don't know.

i took 800mg seroquel tops. but our conditions are different.

i like risperdal. you may want to consider it. it is weight neutral and helped a lot with all my symptoms.

-- loon --

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Well I've made the change to prozac.

I was on 60mg Paxil, now im on 80mg prozac. The change over was incredibly smooth.

As for the AAP, I'm still on 1500mg Seroquel/day, but at my next appointment we are going to draw up a plan to transaition over to abilify.  This may involve an endpoint with a low seroquel dose + abilify or something. 

The seroquel works pretty well, its just that on the paxil/seroquel combo I gained a lot of weight and was a little too sedated. But you expect that on a higher dose.

As for risperdal, my p-doc feels that its a good medication, but not much better than serqouel for weight gain.  Certainly an option if the abilify doesnt work.

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  • 11 months later...
Guest spittykitty

Hello.

I have been diagnosed with depression and anxiety, and I'm OCD as well but never really got into that with my doctor. I had been on paxil (called Aropax here) for 4 years before changing to another medication due to weight gain and loss of libido.

The paxil worked wonders for my depression, while I was on the medication I never had any problems with it. I still had some anxiety problems but mostly social anxiety. I still don't go out much socialising - I'm not so afraid of it now, I just prefer to stay at home and do my own thing. I like my own company if you get what I mean. Also with paxil I found I slept too much. I would often be really tired and have to have a catnap, and some days I practically slept all day for no reason. I felt very healthy, so could only attribute the sleeping to the medication. The OCD seemed to ease a bit, I wasn't quite so obsessive and could actually leave the house a bit messy for the first time! My OCD used to drive my husband crazy. Things were ordered and alphabetised or colour coordinated, even the most stupid things like the towels in the bathroom HAD to be the same colour or I just had to change them. When I was younger I had to check the stove was off in the kitchen before I went to bed, otherwise I would have this awful feeling the house would burn down during the night and I could not sleep.

I'm now on a different medication, sorry I think its called Citalopram? I asked my doctor to change my meds as the paxil turned me into a little fat pudding with no libido! I've since lost the weight (20kgs), but my libido is still dead much to my husbands despair! My depression has still never returned but I wonder if I'll ever get my libido back.

Guess we can't have everything huh?

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Risperdal really helped with my OCD, and kicked it pretty fast. My current pdoc took me off of it, and switched to seroquel, but I'm feeling the symptoms returning, and wonder what he'll do next. I'd suggest that as another resort.

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