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Has anyone else experienced anger, irritability, and impatience on Lamictal 150 mg? 

 

Thank You,

Lisa

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Starting up Lamictal can be stimulating, which I felt until I was on a stable dose for a while.

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Yes. LTG made me feel worse until it made me feel better. It’s a tricky med to titrate. Until you get to the dose that’s going to be therapeutically useful to you, it’s likely that you’ll feel all kinds of cranky. 

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3 hours ago, lisa2712 said:

Has anyone else experienced anger, irritability, and impatience on Lamictal 150 mg? 

 

Thank You,

Lisa

When did you start and when did you hit 150? 

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1 hour ago, Iceberg said:

When did you start and when did you hit 150? 

I started over 1 year ago, and I stayed on 125 mg for about 3 months. I started on 150 mg 2 weeks and 2 days ago. I take it in the morning. 

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35 minutes ago, lisa2712 said:

I started over 1 year ago, and I stayed on 125 mg for about 3 months. I started on 150 mg 2 weeks and 2 days ago. I take it in the morning. 

It makes sense to me that as your body adapts to this new higher dose, there will be some growing pains. 

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On 5/2/2019 at 10:41 PM, lisa2712 said:

I started over 1 year ago, and I stayed on 125 mg for about 3 months. I started on 150 mg 2 weeks and 2 days ago. I take it in the morning. 

I always found that LTG caused some "ripples" for a good 2-3 weeks after a dose change up or down. Either way it would always make me anxious/agitated. Then everything would kind of just calm down. It wasn't as bad at 150mg and up.

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1 hour ago, browri said:

I always found that LTG caused some "ripples" for a good 2-3 weeks after a dose change up or down. Either way it would always make me anxious/agitated. Then everything would kind of just calm down. It wasn't as bad at 150mg and up.

I am also having an uncomfortable tightness in my neck. It isn’t going away. I have been on LTG 150 mg for about 2.5 weeks. I can’t see my psychiatrist for another 2 weeks. I’m trying to stick with this med because it’s not interfering with my diet and weight loss, and my only other option with my current psychiatrist is Abilify, which I fear will be worse and will make me unable to lose weight. 

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15 hours ago, lisa2712 said:

I am also having an uncomfortable tightness in my neck. It isn’t going away. I have been on LTG 150 mg for about 2.5 weeks. I can’t see my psychiatrist for another 2 weeks. I’m trying to stick with this med because it’s not interfering with my diet and weight loss, and my only other option with my current psychiatrist is Abilify, which I fear will be worse and will make me unable to lose weight. 

Starting up, LTG can also cause some muscle pain. Although, I seem to recall experiencing it mostly in the lower back, but it can happen anymore. Now, neck stiffness CAN be a sign of something more serious if it is accompanied by headache, increased sensitivity to light, nausea, vomiting, confusion, and drowsiness. Which is funny because headache, nausea, and drowsiness are already considered to be non-serious side effects, but taken together in combination with increased sensitivity to light and confusion, this would be something you need to report to your doctor.

I would say if you've been on 150mg LTG for a month and you're still having the neck pain and it really isn't tolerable, then LTG may not be an option for you. However, I'm inclined to think it will go away. After I adjusted to it, the only two side effects I ever experienced from Lamictal were an occasional headache day, and they would be bad-ish headaches that would come and go, kind of elusive, and they don't respond well to things like Tylenol; as well as issues with word recall (cognition issues). The word recall (tip of your tongue sensation) problem was more common than the headaches.

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Posted (edited)
1 hour ago, browri said:

Starting up, LTG can also cause some muscle pain. Although, I seem to recall experiencing it mostly in the lower back, but it can happen anymore. Now, neck stiffness CAN be a sign of something more serious if it is accompanied by headache, increased sensitivity to light, nausea, vomiting, confusion, and drowsiness. Which is funny because headache, nausea, and drowsiness are already considered to be non-serious side effects, but taken together in combination with increased sensitivity to light and confusion, this would be something you need to report to your doctor.

I would say if you've been on 150mg LTG for a month and you're still having the neck pain and it really isn't tolerable, then LTG may not be an option for you. However, I'm inclined to think it will go away. After I adjusted to it, the only two side effects I ever experienced from Lamictal were an occasional headache day, and they would be bad-ish headaches that would come and go, kind of elusive, and they don't respond well to things like Tylenol; as well as issues with word recall (cognition issues). The word recall (tip of your tongue sensation) problem was more common than the headaches.

As of today, I’m 3 weeks on the LTG 150 mg. A month is 3-4 weeks, so I don’t know if I should give it another week, but the side effects are starting to wear on me. I occasionally have slight headaches, but nothing serious. I am more tired, I want to sleep more, but I have things I have to do. 

 

Next, my only other option is Abilify. I may change doctors. I still want to continue losing weight. 

 

 

Edited by lisa2712

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4 hours ago, lisa2712 said:

As of today, I’m 3 weeks on the LTG 150 mg. A month is 3-4 weeks, so I don’t know if I should give it another week, but the side effects are starting to wear on me. I occasionally have slight headaches, but nothing serious. I am more tired, I want to sleep more, but I have things I have to do. 

 

Next, my only other option is Abilify. I may change doctors. I still want to continue losing weight. 

 

 

question to @lisa2712. Are you currently still taking Cymbalta?

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42 minutes ago, browri said:

question to @lisa2712. Are you currently still taking Cymbalta?

Yes, I take Cymbalta 30 mg.

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@lisa2712 Was the 100mg not working? I was on 100mg for a long time and it's only been until now that I've had to go up to 150mg. I think the ideal range is 100mg-300mg for Lamictal, just a thought, maybe lower is better for you.

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A month is 4 to 5 weeks. Every time I increased it I had problems for a few weeks, mainly interminable insomnia and headache. For seizures the dosing is higher, I found 300 mg easy to tolerate after a month had passed. 

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3 hours ago, Blahblah said:

@lisa2712 Was the 100mg not working? I was on 100mg for a long time and it's only been until now that I've had to go up to 150mg. I think the ideal range is 100mg-300mg for Lamictal, just a thought, maybe lower is better for you.

My psychiatric PA tells me that the therapeutic dose is 150- 400 mg, and I didn’t think the 100 mg dose was working.

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14 hours ago, lisa2712 said:

My psychiatric PA tells me that the therapeutic dose is 150- 400 mg, and I didn’t think the 100 mg dose was working.

Generally for bipolar disorder they want you to try and get to 200mg for a few weeks before you totally give up on it. After you get past the 100-150mg hump, it starts to become more calming and have less of a ripple effect with dose increases. However, statistically speaking doses over 200mg only help a small portion of people with mood disorders. Doses from 300mg to 600mg are typically reserved for epileptic conditions.

However, for treatment-resistant depression or in an adjunctive scenario, doses of 100-150mg can be used with much success, sometimes even just 75mg for some people.

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It’s harder now, because I can’t see my psychiatrist, because I changed insurance, and it will take about 2 weeks for me to get my new insurance card with my member info on it, then another 10 days for me to get an authorization to see the psychiatrist. I haven’t seen her in about 2 months. 

My psychiatric PA told me I need a mood stabilizer, which is why she put me on it, and is trying to get me on a therapeutic dose. I wasn’t feeling depressed, because I’m on a SNRI, but I’m always on edge and anxious in social places around people. I’m also sound sensitive.

The LTG 150 mg has made me less overwhelmed and over-stimulated by people . I went to the mall yesterday and I noticed I was less anxious. 

If I can’t tolerate 150 mg of LTG, my only other option ( with this psychiatrist) is Abilify. 

 

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19 hours ago, lisa2712 said:

It’s harder now, because I can’t see my psychiatrist, because I changed insurance, and it will take about 2 weeks for me to get my new insurance card with my member info on it, then another 10 days for me to get an authorization to see the psychiatrist.

Authorization to see a psychiatrist. Are you on an HMO insurance that you need a referral to see a specialist?

19 hours ago, lisa2712 said:

I haven’t seen her in about 2 months. 

...which really sucks when you're in the middle of a transition. Believe me, I feel you here.

19 hours ago, lisa2712 said:

My psychiatric PA told me I need a mood stabilizer, which is why she put me on it, and is trying to get me on a therapeutic dose. I wasn’t feeling depressed, because I’m on a SNRI, but I’m always on edge and anxious in social places around people. I’m also sound sensitive.

The LTG 150 mg has made me less overwhelmed and over-stimulated by people . I went to the mall yesterday and I noticed I was less anxious. 

If I can’t tolerate 150 mg of LTG, my only other option ( with this psychiatrist) is Abilify. 

 

I think it's always a good decision to try something like lamotrigine to see if it does make a difference. People are so resistant to mood stabilizers because they think the mood stabilizer comes with a label of "unstable mood" or bipolar disorder, but statistically, over half of bipolar diagnoses start out as unipolar depression because the positive symptoms aren't always immediately apparent. Even for people who really don't have mood swings, mood stabilizers still can do a great amount of good.

What you're describing of your experience with LTG reminds me of how it felt to me. Things just kinda rolled off your shoulder easier. Normally when certain situations would get you in a rut, with LTG you don't seem to get "stuck in a hole". And this is in line with it's indication "to delay the time to a mood episode in those with bipolar disorder" or rather to "keep things at bay".

I would say though that if you always feel on-edge or anxious in social situations, I'm not entirely sure why your pdoc is considering Abilify as an option. It can be very stimulating at the lower doses for some people. But each person is different. It's not even "your mileage MAY vary" it's "your mileage WILL vary"

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5 hours ago, browri said:

Authorization to see a psychiatrist. Are you on an HMO insurance that you need a referral to see a specialist?

...which really sucks when you're in the middle of a transition. Believe me, I feel you here.

I think it's always a good decision to try something like lamotrigine to see if it does make a difference. People are so resistant to mood stabilizers because they think the mood stabilizer comes with a label of "unstable mood" or bipolar disorder, but statistically, over half of bipolar diagnoses start out as unipolar depression because the positive symptoms aren't always immediately apparent. Even for people who really don't have mood swings, mood stabilizers still can do a great amount of good.

What you're describing of your experience with LTG reminds me of how it felt to me. Things just kinda rolled off your shoulder easier. Normally when certain situations would get you in a rut, with LTG you don't seem to get "stuck in a hole". And this is in line with it's indication "to delay the time to a mood episode in those with bipolar disorder" or rather to "keep things at bay".

I would say though that if you always feel on-edge or anxious in social situations, I'm not entirely sure why your pdoc is considering Abilify as an option. It can be very stimulating at the lower doses for some people. But each person is different. It's not even "your mileage MAY vary" it's "your mileage WILL vary"

Yea, I was just switched to an HMO insurance. 

LTG 150 mg has made a positive difference, even though it's a low therapeutic dose. My only problem is one side effect, which I can't deal with. :( 

Yea, I'm not really sure why my psychiatric PA tells me I need a mood stabilizer, but I have felt less anxious and better mentally on LTG 150 mg, more pulled together rather than being all over the place. I had a previous (over 10 years ago) psychiatric nurse practitioner tell me that I need to be on an Antipsychotic, and at the time it puzzled me, because I was going to her for social anxiety. 

Yes, I think my last option is Abilify. If Abilify doesn't work out, I'm probably changing psychiatrists. I took it for 2 weeks and did feel more anxiety, but others here have told me it can be more calming at higher doses. I want to continue with my weight loss and caring about my diet. Seroquel made me not care about my diet or losing weight, which is why I went off it. The same thing happened when I was on a higher dose of clonazepam. I have 100 lbs to lose before I'm at a healthy weight and BMI. 

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5 hours ago, browri said:

 

I would say though that if you always feel on-edge or anxious in social situations, I'm not entirely sure why your pdoc is considering Abilify as an option. It can be very stimulating at the lower doses for some people. But each person is different. It's not even "your mileage MAY vary" it's "your mileage WILL vary"

Yea, that's one of my worst faults, always being on-edge and anxious in social situations, and not being able to relax like a "normal" person. It was nice to be able to relax a little bit while I was on LTG 150 mg. I was able to sit down at the mall and relax, although my anxiety was still there and increasing the longer I stayed in the mall. 

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