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Hi all,

I'm a 20+ year sufferer of extremely TRD and am trying LSD (1P-LSD, more specifically) microdosing to help lift my mood and combat anhedonia. I'd love to know if anyone else has tried this. Specifically:

  • what was your regimen? e.g. every 3 days?, dosage, substance, method
  • did any initial beneficial effects increase over time? if so, over what kind of period?
  • did you develop a tolerance?
  • did it help with your anhedonia?
  • did you try more than a microdose e.g. 1/4, 1/2 or even a whole tab? If so, how was that therapeutically?

FTR, I'm taking 10ug (1/10th of a tab) every 3 days using the volumetric method. I felt notably more energetic and less severely depressed within an hour of dosing. This persisted for ~ 14 hours. I couldn't sleep. Now, the next day, I feel kind of back to normal (i.e. feel very depressed and anhedonic), which is very demoralising.

Thanks, Pete

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I locked this.  Until there's some kind of hard science and peer reviewed research on this we would really rather not have discussions on this subject here.

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