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Is it possible to develop akathisia on Rexulti or any other antipsychotic after 8 months of use? I literally have had NO side effects from Rexulti before 2 weeks ago. I am really scared that I will have to stop Rexulti since it has been a GOD SEND. Tomorrow is my first day of my new job and I cannot be feeling so....restless!!!!!!!!!!!!!! I can't contact my doctor. Is there anything I can do in the mean time? Could this restlessness just be anxiety?

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if this is EPS, you can try something that is anticholenergic. Like a first gen antihistamine.

Could just be anxiety however. If you go have some hydroxyzine lying around, that is an antihistamine that is actually approved for anxiety. Two birds, one stone.

Edited by argh
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If you can't contact your psychiatrist maybe you could contact your general practitioner. Some meds that help akathisia are the type a GP would be happy to prescribe. Propranalol for example.

I was convinced Rexulti gave me some kind of anxiety/restlessness/akathisia. Pacing around contantly etc. But the pdoc didn't think so. It's hard to figure out which med is doing what and even if meds are to blame at all. And even if you're convinced it's hard to prove you're right.

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