Jump to content
CrazyBoards.org

Sign in to follow this  
mikl_pls

Meds for essential tremor that AREN'T beta-blockers

Recommended Posts

I've tried quite a few meds, including but not limited to many beta-blockers (atenolol, propranolol, metoprolol, acebutolol, nadolol, currently on pindolol), anticonvulsants (topiramate, levetiracetam, gabapentin, and primidone), and benzos (pretty much all of them!), and haven't had good results.

  • Beta-blockers, even pindolol with its intrinsic sympathomimetic activity, causes bradycardia.
  • Topiramate (Topamax) makes me STUPID AF.
  • Levetiracetam (Keppra) makes me suicidal.
  • Primidone (Mysoline), while it works really well, the cognitive issues are EONS worse than that of topiramate.
  • Gabapentin (Neurontin) does nothing for me much except put weight on me, but then again, I didn't pay attention to my tremor at the time, so it could be worth another try.
  • Benzos don't do anything, which I wasn't taking the benzo primarily for the tremor anyway...

I've read up on other treatments of essential tremor, and I'm not too keen on using clozapine (Clozaril), mirtazapine (Remeron), or alcohol...

Does anyone know of any other treatments that would work? Or if I should retry gabapentin? I literally spilled my drink all over myself tonight when I went out to eat with my boyfriend. I'm sick of dealing with this.

Share this post


Link to post
Share on other sites

Maybe lyrica as its supposedly stronger than gabapentin.

im not one to ever not recommend gabapentin, so yes i think it’s worth a shot.

  • Thanks 1

Share this post


Link to post
Share on other sites
2 minutes ago, argh said:

Maybe lyrica as its supposedly stronger than gabapentin.

im not one to ever not recommend gabapentin, so yes i think it’s worth a shot.

I may ask either my pdoc or my neurologist (I see pdoc sooner I believe) about trying gabapentin then, and if it doesn't work, I will try Lyrica.

Keppra helped a little, but the benefits vs the detriments just weren't worth it. I was horrendously suicidal when I was on that med.

Edited by mikl_pls

Share this post


Link to post
Share on other sites
16 hours ago, mikl_pls said:

I may ask either my pdoc or my neurologist (I see pdoc sooner I believe) about trying gabapentin then, and if it doesn't work, I will try Lyrica.

Keppra helped a little, but the benefits vs the detriments just weren't worth it. I was horrendously suicidal when I was on that med.

Zonegran? That was the only other Hail Mary I found that wasn’t rediculous 

  • Thanks 1

Share this post


Link to post
Share on other sites
2 hours ago, netsavy006 said:

Aren't the EPS meds (cogentin and artane for example) used off label for tremors?

I forgot about those... I have taken Cogentin for tremor, and while it works, the drying side effect is somewhat tolerable, yet losing the ability to focus close up is intolerable. It makes me literally have to wear reading glasses on top of my contacts. I've never taken Artane because my pdoc doesn't want me to. She says it's addictive. (?)

Cogentin could probably be a good med to use PRN for tremor, like if I'm about to go somewhere where I feel I would be judged by my tremor or if I need really fine motor control. Yet I'm not closed to trying Artane, because I know my NP can probably prescribe it.

Thanks for the suggestion!

1 hour ago, Iceberg said:

Zonegran? That was the only other Hail Mary I found that wasn’t rediculous 

Aha! Zonegran! I forgot, I did try that too and it helped me a lot. How could I have forgotten this medicine?

My neurologist took me off Zonegran 400 mg and put me on Topamax 200 mg, and eventually 400 mg. I tolerated Topamax 200 mg worse than I tolerated Zonegran 400 mg. I had no cognitive issues on Zonegran, surprisingly, but on Topamax, it's literally like an alzheimer's pill (with the addition of primidone).

Zonegran is definitely worth another go! Thank you for reminding me about this!

 

  • Like 1

Share this post


Link to post
Share on other sites
On 7/9/2019 at 12:04 AM, Persona_Is_Life said:

Mirapex? 

That was a good medicine for my mood, but it unfortunately didn't do anything for my tremor, and it made me eat and spend compulsively. Apparently dopamine agonists/partial agonists just aren't for me... lol. Thanks for the suggestion!

I've actually thought about going back on Rytary (normal Sinemet doesn't do anything for me). At the lowest dose 3x/day, I got some benefit without the compulsivity associated with dopaminergics, and I felt like if my pdoc had pushed the dose a little higher, I might've gotten way more benefit from it, but she wouldn't do it for some reason. I might bring it up to my neurologist.

My sleep doctor gave me Requip for tremor, as he is convinced I have a Parkinsonian element to my tremor. He also gave me iron tablets, but those made my breath smell bad and my mouth taste bad, very unpleasant.

Share this post


Link to post
Share on other sites

I might have missed it in your signature but what about Azilect (rasagiline) or Amantadine? 

There's also Stalevo. It's Carbadopa/Levodopa/Entacapone. 

  • Thanks 1

Share this post


Link to post
Share on other sites
4 hours ago, Persona_Is_Life said:

I might have missed it in your signature but what about Azilect (rasagiline) or Amantadine? 

There's also Stalevo. It's Carbadopa/Levodopa/Entacapone. 

I've been curious about Azilect actually--heck, even selegiline (Eldepryl) too--as well as amantadine. Both seem like they could possibly do something good for me.

I don't know if I'm ready for Stalevo yet... lol.

Thanks for the suggestions! I didn't think of those.

  • Like 1

Share this post


Link to post
Share on other sites
16 hours ago, mikl_pls said:

I've been curious about Azilect actually--heck, even selegiline (Eldepryl) too--as well as amantadine. Both seem like they could possibly do something good for me.

I don't know if I'm ready for Stalevo yet... lol.

Thanks for the suggestions! I didn't think of those.

Anytime. :)

  • Like 1

Share this post


Link to post
Share on other sites
12 hours ago, looking for answers said:

i believe the med im starting for my concussion also works for tremors and a variety of things, amantadine

Yes, I've read about that. I just added that to my med list I'm going to ask about for tremor. Thanks! :) 

Share this post


Link to post
Share on other sites
6 hours ago, mikl_pls said:

Yes, I've read about that. I just added that to my med list I'm going to ask about for tremor. Thanks! :) 

im going to start the med tommorow, remind me to let you know how it goes

  • Like 1

Share this post


Link to post
Share on other sites
1 hour ago, looking for answers said:

im going to start the med tommorow, remind me to let you know how it goes

Will do!

  • Like 1

Share this post


Link to post
Share on other sites

did you try this? I really noticed no effects, i dunno mood wise i just feel a bit odd, but i have so much going going on im doubting its the med.

less jittery>? no actually a bit shaky

BUT BUT BUT after about 2 weeks on the med, and it says you can maybe feel "energy" in a few days, it likely takes a few weeks to kick in.

I did notice that when im trying to do cognitive tasks, i get less dizzy, blurred vision, headaches, etc. I still have the cognitivie issues..........But those symptoms subsided........so i guess for the Neuro fatigue, it is working........

  • Like 1

Share this post


Link to post
Share on other sites
1 hour ago, looking for answers said:

did you try this? I really noticed no effects, i dunno mood wise i just feel a bit odd, but i have so much going going on im doubting its the med.

less jittery>? no actually a bit shaky

BUT BUT BUT after about 2 weeks on the med, and it says you can maybe feel "energy" in a few days, it likely takes a few weeks to kick in.

I did notice that when im trying to do cognitive tasks, i get less dizzy, blurred vision, headaches, etc. I still have the cognitivie issues..........But those symptoms subsided........so i guess for the Neuro fatigue, it is working........

Glad to hear it's working at least partially for you.  I think I may ask to try it for tremor. It has anticholinergic properties, just not as strong as Cogentin (which causes blurry vision, dry mouth, can't focus up close, etc.). Either that or I may try Artane, another anticholinergic.

Share this post


Link to post
Share on other sites
5 minutes ago, mikl_pls said:

Glad to hear it's working at least partially for you.  I think I may ask to try it for tremor. It has anticholinergic properties, just not as strong as Cogentin (which causes blurry vision, dry mouth, can't focus up close, etc.). Either that or I may try Artane, another anticholinergic.

I know it has those properties which is why I questioned its use. Bc that’s some of the symptoms were trying to get rid of

Share this post


Link to post
Share on other sites
6 hours ago, looking for answers said:

I know it has those properties which is why I questioned its use. Bc that’s some of the symptoms were trying to get rid of

I've always been curious about amantadine, I've always wanted to try it to see how it helps my ADHD and energy as it's one of the few psych/neuro meds I've not taken. But I certainly don't want to be more jitttery... lol.

I think for your case, its the NMDA antagonism they're going for, possibly, which requires kinda high doses (up to 400 mg max). Why they haven't just given you memantine instead is a mystery (it's much more potent a NMDA antagonist). Also, magnesium could possibly help you too as it is a natural NMDA antagonist.

  • Like 1

Share this post


Link to post
Share on other sites
6 minutes ago, mikl_pls said:

I've always been curious about amantadine, I've always wanted to try it to see how it helps my ADHD and energy as it's one of the few psych/neuro meds I've not taken. But I certainly don't want to be more jitttery... lol.

I think for your case, its the NMDA antagonism they're going for, possibly, which requires kinda high doses (up to 400 mg max). Why they haven't just given you memantine instead is a mystery (it's much more potent a NMDA antagonist). Also, magnesium could possibly help you too as it is a natural NMDA antagonist.

Im Actually in magnesium as wel at the momement. I dunno on the jitters it’s like literally hand shaking, I don’t feel jittery . It comes on when I’m trying to do therapy so take it with a grain of salt. And they have never mentioned memantine only this

  • Like 1

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Sign in to follow this  

  • Similar Content

    • By Mistylumos
      First time poster here. I have bipolar 1, diagnosed last year after some horrible psychotic/manic episodes. I was put on lexapro which made me go insane and then put on zyprexa 10 mg which I abruptly stopped (I didnt get that you cant do that) which then again made me go crazy. Right now I am on Rexulti 1.5 mg and Seroquel 37.5 mg (I am tapering the Seroquel slowly to come off of it). I know these are low doses but I tend to be very sensitive to meds. The highest does of seroquel I was on was 300. I am not having any weird psychotic symptoms or manic feelings but am struggling with some depression. I am really unhappy with the weight gain from the antipsychotics. I have gained 10 lbs and from what I read all the APS will put weight on you. I also do not like how tired I feel. When I first started taking them I think the Rexulti was more activating, I actually felt jittery and seemed to be getting more stuff done, but now I just feel lazy and unmotivated. I was curious about trying Lamictal, and I was wondering if it would be possible to take that instead of the Rexulti. The only thing I worry about is I hear it impacts your cognition and I am starting school soon. Has anyone managed Bipolar 1 without a AP? Is it possible to just be on lamictal? I won't try antidepressents again after what happend with the lexapro. 
    • By Blahblah
      Maybe a random place to post, but I'm wondering if anyone here has had kidney disease/failure or other kidney problems suddenly arise, due to taking a lot of psych meds? I hear of ppl having liver problems, but not often kidney...
      My GP is concerned about my elevated creatine levels (and other related symptoms) and says she sees this frequently when people take psych meds for many years... She is ruling out other causes, as this doesn't run in my family at all.
    • By Distorted Me
      I know that a lot of bipolar folks take an SSRI as part of their daily regimen of meds and apparently it seems to help.  But there's some growing concern in the pdoc world now that SSRI's may be causing manic symptoms and even directly causing manic episodes.  I was on SSRI's for 10 years before quitting last October.  In chronological order:  Celexa, Zoloft, Celexa again, Lexapro, Zoloft again, Prozac, Zoloft again briefly, back to Prozac to close it out. 
      For me, personally, after stopping them altogether, I was able to see what they were doing to my system.  I truly believe they made me much more unstable and greatly increased compulsiveness and just made a bad situation worse.  Switching from Lexapro to Zoloft sent me immediately full-on hypomanic for over a month in early 2015.  I was high as a kite and on top of the fucking world.  It was unreal and so obvious at the time. From the beginning of it, I was certain something unusual was going on. Now I wasn't diagnosed bipolar yet, just depressed, so I didn't even know what hypomania was then.  It fizzled out eventually (sigh) but I had at least two more, shorter, and less intense episodes late spring 2015.  I've not had anything quite as euphoric as those since.
      My last pdoc expressed some concern about the prozac but wasn't very insistent on me stopping it, just that I would want to eventually.  I've since read that there is increasing concern in the pdoc community.  Yet a lot of bipolar people still take SSRI's and don't seem to have problems. 
      Do SSRI's seem to help your causes?  Do you notice any unusual side effects?  Have any of you stopped taking SSRI's and noticed a change?  Other comments?   This could be interesting.
    • By Candy6544
      So I just started Latuda and I am an avid user of alcohol and marijuana (its legal in my state)
      I currently take geodon, lamictal, and lithium but I just added latuda
      everything seemed like it was actually working great with Latuda but after I used "weed" and alcohol my brain is in bad shape and slowly getting better 
      It really left my mind foggy and inattentative in the morning because of  combining the marijuana and alcohol with it.
      at first it was going great but mixing those things with it really left my mind not all there  
      moral of the story if you take other bipolar/schizophrenia meds alongside Latuda DO NOT do any marijuana as well it'll ruin your brain over time trust me. Other antipsychotics can cause this effect too
      i hope this helps those who are struggling with substance abuse alongside any of these meds because they can help you greatly but marijuana will fry with your brain with them overtime mixing them
    • By gazelle
      Hi all I'm new here first diagnosed with ADHD I and now with bipolar 2 and anxiety. 
      I'm having some trouble with the meds that I'm on. I'm taking between 25 and 50 mg of Vyvanse daily. It helps with my depression, ADHD, and binge eating, but even though I'm a big girl I'm very sensitive to meds in general so my dose is fairly low. Since I was just diagnosed with bipolar in April, the psychiatrist added a mood stabilizer which is Lamictal. It is making me super sleepy but I'm not sleeping well at night. I already know that I don't do well with anticonvulsants because I can't even take 25 mg of Topiramate without being zombie like tired all day. Also my Promethease test shows that I have a gene for processing anticonvulsants less efficiently than other people. 
      Lamictal seems to be doing the same thing that topiramate does to me, at least to some extent. I am also on 60 mg ER of propranolol at bedtime for a fast pulse and anxiety. I'm averaging about 5 hours of sleep right now and that is not working well for me.
      I am really wanting to request doing something different than this Lamictal. I'm definitely feeling more stable, but I cannot function as a zombie with a four-year-old. What would you suggest that I talk with my pdoc about when I go back, if anything? I've made it up to 75 mg of Lamictal and it's killer. My only option I'm thinking is to quit taking it in the morning and try it at night, but that never helped with Topiramate either.
      I will say that I struggle more with depression than hypomania but I do have hypomanic episodes--at least a few year with the seasonal changes and sometimes I wonder if I don't rapid cycle as well. I will also add that a concern for me would be weight gain because I'm already in the obese category, though I am losing weight--only with the help of the Vyvanse and dealing with the binge eating and ADHD for the last couple of years since I was diagnosed.
      Thanks!
       
       
       
       
       
×
×
  • Create New...