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My son is turning 4 in a week and I am still struggling with depression. Just wondering if you guys had advice on what meds I could try next. 

Paxil, I was on for about 2 years. It worked perfectly but just quit working

Viibryd, I took right after his birth for about a year until it stopped working. 

Zoloft, went to pcp last week and she put me on that. I've only gotten worse with it and tapering off paxil. 

Wellbutrin, not effective 

Celexa, was on for years before pregnancy, mostly for anxiety. No major depression before pregnancy. Not effective anymore. 

Cymbalta, took with viibryd. Not sure if it helped and caused excessive, embarrassing sweating. 

Gabapentin and buspar, not effective. 

Prozac, capsules give me that pill stuck in my throat feeling and heartburn. Could try a different form. Cant remember when I told it last or its effects. 

Trintellix, not effective 

I think that's all. 

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Atypical antipsychotics with known antidepressant properties such as seoquel, geodon, abilify, rexulti, latuda, vrayla?

if you had a partial response to an ad, those could be used to augment the ad vs monotherapy.

low dose lithium?

an anticonvulsant like lamictal or topamax?

 

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1 hour ago, argh said:

Atypical antipsychotics with known antidepressant properties such as seoquel, geodon, abilify, rexulti, latuda, vrayla?

if you had a partial response to an ad, those could be used to augment the ad vs monotherapy.

low dose lithium?

an anticonvulsant like lamictal or topamax?

 

I messaged my dr about abilify. Hadn't thought about lithium or lamictal. Thanks. 

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1 hour ago, curve31 said:

I messaged my dr about abilify. Hadn't thought about lithium or lamictal. Thanks. 

I’d add in Effexor to the list maybe 

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2 hours ago, curve31 said:

I messaged my dr about abilify. Hadn't thought about lithium or lamictal. Thanks. 

good luck

this is a site that i usually reference.  don't freak at the header, it isn't actually about bipolar 2. that's just sort of done for SEO purposes.

it's basically  for those of us that have AD poopout, no effects on ADs,  bad reactions on ADs, cyclical features, mood instability, etc..but aren't bipolar proper.

i'm no doc, take that plus any advice here with a grain of salt. read up, think for yourself, etc.

https://psycheducation.org/

There's a good number of us on the boards in that situation who have found relief (or close to it) via mood stabilizers instead of ADs.

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13 hours ago, curve31 said:

My son is turning 4 in a week and I am still struggling with depression. Just wondering if you guys had advice on what meds I could try next. 

According to what you listed, you haven't tried Luvox or Lexapro (both SSRIs)......Maybe worth a try?

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Posted (edited)
7 hours ago, DammitJanet said:

There’s also always tricyclics and maoi’s. 

Yes, I agree. You've tried enough first-line agents to justify moving on to second-line and third-line agents (TCAs and MAOIs).

Edited by mikl_pls

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15 hours ago, argh said:

good luck

this is a site that i usually reference.  don't freak at the header, it isn't actually about bipolar 2. that's just sort of done for SEO purposes.

it's basically  for those of us that have AD poopout, no effects on ADs,  bad reactions on ADs, cyclical features, mood instability, etc..but aren't bipolar proper.

i'm no doc, take that plus any advice here with a grain of salt. read up, think for yourself, etc.

https://psycheducation.org/

There's a good number of us on the boards in that situation who have found relief (or close to it) via mood stabilizers instead of ADs.

@argh I can't believe you haven't told me about this site!!! I stayed up late last night (oops) reading it. It's good!

One downside of mood stabilisers is if you're wanting to have more children they're not recommended in pregnancy and breastfeeding. :( whereas there are a few SSRIs that are considered safe. 

Someone else mentioned lexapro/escitalopram. I think this is the best SSRI if you have anxiety with depression. I took it for quite a while, it worked as well as any other SSRI in my case. But it made me DOG tired. It's notorious for making people tired. Which personally I found a real struggle when looking after a toddler all day. You may find it different, but it's something to keep in mind I guess. 

Tbh I think if you've already tried a few SSRIs then it's worth trying something different. 

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12 minutes ago, Melancholya said:

@argh I can't believe you haven't told me about this site!!! I stayed up late last night (oops) reading it. It's good!

One downside of mood stabilisers is if you're wanting to have more children they're not recommended in pregnancy and breastfeeding. :( whereas there are a few SSRIs that are considered safe. 

Someone else mentioned lexapro/escitalopram. I think this is the best SSRI if you have anxiety with depression. I took it for quite a while, it worked as well as any other SSRI in my case. But it made me DOG tired. It's notorious for making people tired. Which personally I found a real struggle when looking after a toddler all day. You may find it different, but it's something to keep in mind I guess. 

Tbh I think if you've already tried a few SSRIs then it's worth trying something different. 

ha! i practically tell everyone. not sure how i missed you :)

His books are quite good too. All the info is on the site, but they're a bit deeper (one is more psych/therapist focused) and more organized.

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30 minutes ago, argh said:

ha! i practically tell everyone. not sure how i missed you :)

His books are quite good too. All the info is on the site, but they're a bit deeper (one is more psych/therapist focused) and more organized.

Yeah I was considering getting one of his books! 

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1 hour ago, Melancholya said:

Yeah I was considering getting one of his books! 

I like detail so my favorite one is a spectrum approach to mood disorders.

Why am i still depressed was the easiest read, but it's 2006 so a bit dated. i don't recall if the guy loved himself some lamotrigine back then or not.

Bipolar not so much is also an easy read, a bit on the drier side though.

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