Have any of you had or have read of gabapentin being of use as an adjunctive therapy for people with treatment resistant depression/anxiety/bipolar?
I have been doing research and some sources say it helps, others say there is no strong clinical proof. I think a lot of the conflicting reports I have seen has to do with it simply not being studied en mass.
Any advice/experiences regarding this? If so, what was your dosing?
I'm having a hell of a hard time and experiencing rather weird symptoms. Whether they've anything to do with Mirtazapine (Remeron) is something that I strongly feel but can't quite convince any doctor of. I was put on 15 mg of it in spring 2015 for depression and a severe insomnia - I hadn't slept an hour like since 25 nights back then! The benefits showed immediately within a day and surprised myself and my family. I would sleep well and be in a very happy and cheerful mood. Then however, from summer 2016 I developed some strange food intolerances; caffeine, sugar, fruits containing high amounts of fructose, yoghurt, butter and so on. Eating anything of that would cause me jitteriness and insomnia. I steered clear of those foods. From autumn last year though, a lot of those food intolerances have relented and it changed into intolerance towards medicines and supplements that I was on; the thyroid medicine for hypothyroidism, Vitamin D, Calcium, Vitamin E and could never again tolerate any new medicine or supplement. Symptoms resulting from these are, again, jitters, insomnia and a strange kind of feeling of being struck on the head, like I can't hear anything and the thinking becomes very unclear and blurred. Coupled with this is a weird sensation that if a medicine has any potential side-effect (even physical, such as urine retention), I get it at all costs. So I'm steering clear of the culprits here too. However, avoiding the culprits doesn't end my misery, it just helps in avoiding a whole new set of symptoms, because since autumn 2016 I'm under constant brainfog anyway, have heart palpitations immediately after every meal (but worst after breakfast), have concentration and focus issues, lead a life without any hobbies, wishes or desires. Nothing excites me, nothing interests me and nothing catches my attention. Leave tasks pending for months (the most unlike me habbit), have badly lost my sense of humour. My sense of humour was something that I literally used to pride on, and friends from around the world would call me to fresh up if they were having a dull day. My mind feels numb, although it isn´t as if it´s the sedating effect of the Mirtazapine because 90% percent of the nights I don´t sleep well, and on a lot of nights I feel as if I´m asleep with an awake mind! The GP who put me on it considered it to be just the effects of anxiety and depression and recommended the doubling of the dose to 30 mg. When I contested that, given that I´ve my doubts of a lot of these issues being brought upon by Mirtazapine itself, she referred me to a psychiatrist. He too strongly denies of Mirtazapine having any hand to play on it and instead thinks it´ll be best to combine it with another antidepressant for day-time. He put me on Paroxetine, boom, a flood of side-effects! Then changed to Fluoxetine (Prozac) - third day on it and having weird feelings. The heart poundings are one and is in fact making me very depressed and hopeless!
I need some energy, some motivation, some good manic voodoo. Why cant i have that without losing my damn fool mind.?
Hasnt anyone looked at that? Why must I be either lazy and lethargic or 90mph? Im always tired, always fatigued. I need to know how to get my mojo going WITHOUT my kookoo taging along every time. I cant believe nobody has studied this.
This is a long shot, but I figure I can't be the only one who has ever had this thought. Is there a way to induce a state that includes the productivity/happiness of mania - without all the extra bullshit? 😅
Mania is better than any drug, the euphoria is incomparable. Every time I skip a few days of sleep, feel an increase in energy, or anything that might be the beginning of an episode, I think - ''Please let this be the onset of the best feeling in the world. I can't do this shit anymore''. I feel so guilty admitting to that, because I know that being manic and being functional are generally not compatible. I also don't ever want to end up in hospital again, because that never fails to be a de-humanizing experience.
I have not had any symptoms of mania since my last hospital admission, three whole years ago. It was the first and only manic episode that I've ever had, and it lasted for about three months. I feel like I could have avoided hospital completely if I had experienced mania without the accompanying psychosis. If I could just achieve that level of elation without:
rapid speech word-salad delusional beliefs dangerously impulsive acts (e.g. jumping out of a car on the highway because the sky looked beautiful and I wanted a loser look) I look back on those ugly symptoms and I could never cope with them now. I go to college full-time, I work, and I have so much to lose if I lost the ability to communicate with others and behave safely. On the other hand - my life just feels so damn gray and stagnant; I miss feeling invincible.