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5 minutes ago, bpjett said:

Wish me luck! I just want to be able to breathe! 

Fingers crossed! I hope Flonase helps you. Fluticasone will work differently from oxymetazoline in that the former is a glucorticosteroid, and the latter activates alpha adrenergic receptors. Theoretically oxymetazoline should work for this particular side effect because Seroquel is an alpha adrenergic blocker and oxymetazoline should work in the opposite direction in the nasal area to open the airways but in my experience oxymetazoline isn't nearly as potent at opening my airways as fluticasone.

And like I said, if you end up getting regular Flonase and find it to just taste disgusting and leave a chemically floral smell in your nose, make sure you try Flonase Sensimist because it's the same fluticasone but a different "experience" so to speak.

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So I tries the Flonase, unfortunately that didn't work. XR formulation did help a scoche, but not anything to write home for.

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On 8/16/2019 at 6:11 PM, mikl_pls said:

I take Vraylar and don't have any issues with nasal congestion. I also took Latuda and didn't have any problems with nasal congestion with it either.

Levocetirizine (Clarinex) is supposed to be good for nasal congestion (it's an antihistamine that is the successor of Claritin).

They make adhesive nasal strips that work pretty well for me when I have nasal congestion at night. Here are the ones I use. https://www.breatheright.com/ You can usually get them at any drug store or places like Walmart or Target.

 

Levocetirizine is Xyzal, not Clarinex. Clarinex is desloratadine. 

10 hours ago, bpjett said:

So I tries the Flonase, unfortunately that didn't work. XR formulation did help a scoche, but not anything to write home for.

What about Ipratropium (Atrovent)? It dries your nose out far more than Flonase. 

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50 minutes ago, Persona_Is_Life said:

 

What about Ipratropium (Atrovent)? It dries your nose out far more than Flonase. 

I was going to suggest that, I have constantly drippy nose, the nasal steroids help some as does the Cetirizine but the drip does not totally go away. Not until I added Ipratropium Bromide 0.06% spray did my nose dry up and quit dripping.  Ipratropium Bromide spray comes in 2 strengths, the lower strength was not enough but the higher strength, 0.06% works for me.

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On 8/17/2019 at 4:54 AM, bpjett said:

Talked with my pdoc and he suggested that this side effect with lessen over time. We also increased to 150XR in the AM and 100 IR at night.

Has anyone experienced a lessening of side effects from Seroquel over time? Did the XR formulation have less side effects?

Yes, that side effect subsided with time for me.

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Well see my nose isn't runny. It's blocked. Would it help that? I'm taking 300mg XR now, no more IR since the pdoc seemed to think that's a culprit as well.

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6 hours ago, bpjett said:

Well see my nose isn't runny. It's blocked. Would it help that? I'm taking 300mg XR now, no more IR since the pdoc seemed to think that's a culprit as well.

It does for me but I use it with an antihistamine and nasal steroid. A drippy nose is usually not an allergic response but a dysfunction of the CNS called vasomotor-rhinitis or non allergic rhinitis, whereas a blocked nose could be either or both.  I have allergic rhinitis and nonallergic rhinitis. You will have to try it to see if it works for you.

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19 hours ago, Persona_Is_Life said:

Levocetirizine is Xyzal, not Clarinex. Clarinex is desloratadine. 

Derp... thanks for pointing that out! I didn't mean to provide misinformation. I've taken both and get them mixed up often.

19 hours ago, Persona_Is_Life said:

Levocetirizine is Xyzal, not Clarinex. Clarinex is desloratadine. 

What about Ipratropium (Atrovent)? It dries your nose out far more than Flonase. 

6 hours ago, notloki said:

It does for me but I use it with an antihistamine and nasal steroid. A drippy nose is usually not an allergic response but a dysfunction of the CNS called vasomotor-rhinitis or non allergic rhinitis, whereas a blocked nose could be either or both.  I have allergic rhinitis and nonallergic rhinitis. You will have to try it to see if it works for you.

This intrigues me, as I have a chronically runny nose and post nasal drip, as do both my parents. I imagine this is prescription, right?

Also, when I looked it up in Epocrates, it says to take it up to 4 times per day (depending on the indication). Is this how you take it, @notloki? I used to take cromolyn sodium nasal spray, which also requires to be taken qid, but I couldn't keep up with having to take a nasal spray that often per day. It really helped and I could actually smell things around me again (both a blessing and a curse lol)!

 

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I could do fine with twice a day dosing. I used it when the steroid spray was not enough and then you are spraying a lot of volume up your nose.

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My nose was totally blocked when I started taking Seroquel but a few months later it went away.

However in the past few years my nose was severely blocked again and my GP referred me to an Ear Nose and Throat specialist and he said I had lots of polyps in my nose and sinuses. He prescribed oral steroids and a steroid nasal spray which didn't help so I had to have surgery to remove the polyps. However the polyps grew again and 18 months later I had more surgery and this time it was very effective and I can finally breathe through my nose for the past few years. I do use a nasal spray though.

Anyway I don't know if the polyps were linked to Seroquel. It was probably just a coincidence. However I definitely had a really blocked nose when I started taking it in 2005 and it did clear up when I was on it a while

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On 9/12/2019 at 9:48 PM, mikl_pls said:

Derp... thanks for pointing that out! I didn't mean to provide misinformation. I've taken both and get them mixed up often.

This intrigues me, as I have a chronically runny nose and post nasal drip, as do both my parents. I imagine this is prescription, right?

Also, when I looked it up in Epocrates, it says to take it up to 4 times per day (depending on the indication). Is this how you take it, @notloki? I used to take cromolyn sodium nasal spray, which also requires to be taken qid, but I couldn't keep up with having to take a nasal spray that often per day. It really helped and I could actually smell things around me again (both a blessing and a curse lol)!

 

Yes. It's prescription. It's generic though! :)

I think I was instructed to do a max of three times a day, but was also told if I only needed it once or twice a day that's fine too. 

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