Melancholya Posted November 1, 2019 Share Posted November 1, 2019 (edited) I recently changed my dose of bupropion from 150mg a day up to alternating 150 and 300 every other day. I also take lamotrigine at 200mg. A couple days ago I noticed I could feel a vein pulsing in my lower leg. I woke up very early this morning (like 5am-ish) and could feel a lot of veins pulsing in my lower legs. I got so anxious about it I couldn't go back to sleep. The pulsing didn't wake me up but it kept me from falling asleep again. I am really freaking out about heart problems with bupropion because it has increased my heart rate since I started on it. So is this likely to be bupropion? I didn't have any side effects going up to 200mg of lamotrigine. I am skipping my bupropion today to see what happens with the pulsing, and I might just go back to 150 daily from tomorrow. Feeling really disappointed because my mood had improved after making the change to alternating 150/300. It's like life doesn't want me to get better. Edit: I forgot to say I am walking a LOT everyday so I don't believe it's due to a sedentary lifestyle. Edited November 1, 2019 by Melancholya Quote Link to comment Share on other sites More sharing options...
notloki Posted November 1, 2019 Share Posted November 1, 2019 It is common to happen (increased heart rate) at 450 mg, my heart rate was at 111 bpm on bupropion all the time. No one was overly concerned about it. I started taking Abilify and that gave me a hand tremor which is treated by propranolol which lowers my heart rate to 70-80 bpm depending on when I take Adderall. Adderall pushes it to the 80's, otherwise it is (resting) in the 70's. Very common side effect more so at the higher doses (300-450 mg). Quote Link to comment Share on other sites More sharing options...
Gearhead Posted November 2, 2019 Share Posted November 2, 2019 Wellbutrin has raised my blood pressure from the ~ 95/65 that it’s been my entire adult life to ~110/70. I’ve always been somewhat tachycardic, in the range of 80-85/bpm, but now I’m consistently in the 90’s. My doctors are entirely unconcerned. You should talk to your doc if it’s irritating to you, but I don’t think you need to freak out about it. I love Wellbutrin. It’s the only thing that’s touched my depression without having intolerable side effects. Quote Link to comment Share on other sites More sharing options...
Melancholya Posted November 2, 2019 Author Share Posted November 2, 2019 Thanks @notloki and @Gearhead. I know that an increased heart rate is normal on this med but the throbbing in my legs is unusual isn't it? Quote Link to comment Share on other sites More sharing options...
Gearhead Posted November 2, 2019 Share Posted November 2, 2019 The leg thing I’ve not heard of, so yes, you should mention it to your doc. And let us know what he says. Now I’m all curious. Quote Link to comment Share on other sites More sharing options...
Melancholya Posted November 2, 2019 Author Share Posted November 2, 2019 I've been paying attention to it today and I'm wondering if it's actually little muscle spasms. I saw that in the list of side effects. But I don't know for sure and it's worrying me Quote Link to comment Share on other sites More sharing options...
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