Okay, I've always had EXCELLENT blood sugar, and I know the data about Cymbalta and A1C (that there can be an increase, but it's typically marginal and generally considered worth the risk). Anyway, there seems to be a correlation between me starting Cymbalta (initially at 30 mg. coming off Viibryd and gradually getting to my current 90 mg. dosage). At first the blood sugar spikes weren't very big, but now they are...my blood sugar is high way too often. My A1C is still within totally normal range, but it's noticeably up. My pdoc and the NP I see at my primary care doctor both think Cymbalta probably isn't the cause. There is no other reason I can think of. I've lost 20 lbs., my diet hasn't changed. As far as I know there's no infection in my body. Now this has been going on since December. The numbers have only really become concerning to me since April. I used to have blood sugar that often dipped a bit too low, so this is just so weird to me. I was wondering if anyone else has experienced a significant rise in blood sugar on Cymbalta? Nothing else changed with my medication, except I went off Buspar (and I doubt that is a factor). I have tried so many anti-depressants like many of you, and I really like Cymbalta, so I'm really hoping I don't have to go off it, because Viibryd and Trintillex were my other 2 best options, and I had side effects with both of them. I can't do things like Pristiq because of extreme sweating, which is too bad, because that was the only side effect I had. There are very few anti-depressants I haven't tried. I ended up on Cymbalta (and my pdoc, who I have seen for 15 years was shocked we'd never tried it), because we discovered that Viibryd was a big contributor to my tiredness (I have what is currently diagnosed as Idiopathic Hypersomnia, although my doctors believe it could be Narcolepsy II...it's not Narcolepsy I, because I had a Lumbar Puncture. I've also had 2 MSLTs, but my doctor says they are irrelevant, because I was on my meds...they did still show Idiopathic Hypersomnia. After going off all psych meds last Summer (and feeling like I was suffocating most of the time and just feeling like I was living outside my body), I never want to do that again, so I'm content with not knowing which sleep disorder it is since the doctor says it really doesn't make a difference as far as treatment). It was in slowly going back on my medications that I realized Viibryd was making me tired. My pdoc and I also then concluded I no longer needed the Buspar. I haven't missed it at all. Any experiences with blood sugar and Cymbalta would be helpful! I appreciate you all!
I've been wanting to get cats for a long time. However, I am highly allergic (moreso to long hair cats than short hair probably), but I'll most likely need to take Allergy meds everyday, long term.
Does anyone know the contraindications or interactions with psych meds? I don't want to become sedated/groggy. Also, I have Dry eye syndrome, I'm afraid anti-histamines will make it much worse. And Alzheimer's runs in my family, I read somewhere that allergy meds might increase dementia and glaucoma risks? Any insight? @mikl_pls
I've taken Claritin, Allegra and Zyrtec occasionally, not sure which are the safest? I also wonder how safe it is to be using immune-suppressing meds longterm, (like will my allergies or sensitivity increase, or be triggered by other things, if I stop)?
Have a strong itch to drop Effexor...(I won't go cold turkey). It stopped my dysphoric crying spells, but now, 10 months later, I'm feeling increasingly flat, apathetic, numb, no motivation (even after dropping to 75mg). I hate how all A/Ds have this lobotomy effect on me longterm. It's initially fine in acute episodes, I'm not sad now, but I can't function properly, and I continue to score Moderate-Severe on the depression scale.
I think it's counteracting my Ritalin (which I increased to 30-40mg)? I don't want to increase Effexor above 150mg, I'd never be able to go off.
I'm trying dosing at night instead, will this make any difference @mikl_pls ? I skipped yesterday's morning dose (then came the intense nausea, over stimulation & brain slosh awfulness @10 hours later) and I took my dose with dinner.
I'm seriously considering going on low-dose mild SSRI instead (Prozac?) I'm sensitive to meds & side effects, and I'm also VERY worried about withdrawals. Especially from Effexor, they are the WORST, and I just read study that Effexor withdrawal syndrome is not dose-dependent:
Forgot to take Lamictal yesterday (I took my other meds). Holy Hell, I took my dose today (on schedule) and I STILL feel awful!! I've only been on 100mg....I thought Lamictal had a super-long half-life? Yesterday went like this:
10am - up, had breakfast
11am – slight Brain “swishes” started (was out the entire day)
12pm – Stronger Brain zaps start
1:30pm – Lunch (meat, salad/veg)
2:30pm – Sudden extreme exhaustion
4pm - more brain zaps => ZAP ZAP ZAP! 🤯
7pm - Irritability starts
11pm – Tea, bedtime, could not fall asleep (I haven't had insomnia in 2+ years)
...Night sweats…Restless legs.....
12am – Ruminations, feel weepy
..Insomnia ensues…(Toss & turn, sweaty/achey all night)
It's now 12pm,and I am STILL having brain zaps! I worry I’ll never be able ever taper, switch from, or withdraw from this med. You probably think well, with MI, WHY would you ever go off it? For me, longterm, these meds are band-aids. There is always a price. Ok, maybe great at preventing acute/severe depression, but as a result, they rob me of any spark, joy, elation, happiness, libido, sexual sensation/response, feelings of reward, love.... This disturbs me. I used to know what positive emotions felt like…
So I’m stable, existing.....but still lacking will or any interest in living....
Please help. Obstructive sleep apnea condition and chronic migraines with insomnia. Also, I am very nocturnal.By SheltieUnderdog
I'll get to the coinciding physical symptoms eventually. I have always had trouble sleeping through most of the night like the majority of people do with ease and very naturally sleep through the majority of the day when most people are awake. I honestly have always preferred not to see the morning (I find it utterly depressing) except I am obligated to get places like doctor's appointments, stores, and restaurants before they close for the day and I would like the be awake and ready to leave my home by the early afternoon on a consistent basis. Since I was 12 years old, my addiction to being nocturnal and having an abnormal or irregular circadian rhythm has gotten progressively worse. So much to the point where I will fall asleep as the sun is rising and wake up when it's setting or it will be dark again by the time I wake up! I am being deprived of too many things, missing doctor's appointments, or not being able to get my car to the auto mechanic before he / she closes for an oil change. I eventually want to get a part-time job (currently living on SSI) and i imagine that my job would take place in the late afternoon or the evening shift but how could I even hold down a job that was a full-blown a graveyard shift under these circumstances!? My insomnia which can be attributed to the fact that I was formerly diagnosed with bipolar 1 with psychotic features and am now diagnosed with schizoaffective disorder, ocd, and add (possibly adhd). Sometimes if I stay awake later than I really want to (preferably between 1 and 3am to be able to wake up by the early afternoon) then I will just remain awake into the next day in order to guarantee that I will make the appointment or obligation and get to it in a state of sheer exhaustion barely able to follow the doctor or specialist as they're explaining things to me. Sometimes I have gone two or even three nights in a row without getting any shuteye because the appearance of it being nighttime awakens me. The only time that my insomnia (but not the sleep apnea or chronic migraines) was under better control was when I was on court ordered injections which were anti-psychotics and along with outright despising the process of getting those injections, I had a plethora of other side effects like akathisia (inability to sit still), lethargy, fatigue, sedation, and severe weight gain at the same time. I've been on Latuda 20mg for a couple of years now with little to no side effects and I plan to stay on it and never be subjected to having to take anti-psychotic injections ever again after my experiences with them when I had to involuntarily take them by court order.
Now I also have some other issues going on in addition to the insomnia and nocturnal sleep cycle. I have ehlers-danlos syndrome type 3. I was diagnosed with severe obstructive sleep apnea after a sleep study ordered by my pulmonologist in the beginning of 2018 shortly after I got off of the anti-psychotic injections and I was 308 pounds (my heaviest ever weight, my height is 5'8). As of December 2019, my weight is 281 and I've been at a weight set-point since the end of 2018 where my weight is no longer fluctuating anymore (cannot easily lose or gain weight). I hated the mask / cpap machine or was cpap intolerant and sent it back to the surgical supply company within a couple of weeks. My ENT is not recommending the oral surgery or UPPP procedure because of how severe the sleep apnea is and I don't want a tracheotomy. He said that I'm too obese to use Inspire. I can't find an oral surgeon who does maxillomandibular advancement surgery. The obstructive sleep apnea and tmj syndrome which I've suffered from for over a decade combined are giving me chronic migraines and still sometimes when I take my prescription strength pain relievers from my rheumatologist. I wake up feeling like I was hit by an 18-wheeler stumbling to the bathroom sink with my eyelids glued together (look up the medical term blepharitis, I get that in my sleep too). Sometimes the migraines are so bad that I will force myself to eat and drink a small amount and take something like Excedrin PM or other types of nighttime pain relievers and fall back asleep and wake up again slightly less messed up because I had more rest even later in the day. Another major problem is that even if I somehow get a better nights sleep one night, the next night I will be so energized once it gets dark that I will do another all-nighter until the sun is coming up and the cycle or revolving door starts all over again.
I used to be prescribed sedatives like Trazadone and Clonazepam but my new psychiatrist (been seeing her for a little over a year) insisted that I come off of them until the sleep apnea was successfully treated because me taking them before going to sleep with that medical condition was too dangerous. I recently found a dental sleep specialist hours away from where I live which designs oral appliances specifically for treating sleep apnea and tmj syndrome and I've been trying to set up an evaluation but they are forcing me to do another sleep study at home because the last one I did at the sleep lab was in March 2018. I recently went to my local CVS and picked up generic Benadryl or diphenhydramine 50mg and I found something recently at 7-Eleven called doxylamine succinate which is labeled as a strong sleep aid. I am sleeping with a wedge pillow and I eventually want to invest in a bed with an adjustable mattress to keep myself on an incline.
If anyone else has any input that you think could be helpful on how I could fend off the insomnia and be less nocturnal on a consistent basis, it would be appreciated.