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I have problems with increased psychotic symptoms the week before my period.  I know there are several antipsychotics that can be taken prn, but I was wondering if one of them would be better to take in a style similar to Prozac with PMDD, and then tapered off, or if that's even possible.  I was wondering if the PRNs will cause too many withdrawal effects if they are taken for only one week and would make you go nuts if you stopped taking them.  I also take Latuda.  

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Depending on the dose and frequency, you may not get withdrawal from one week of PRNs - depending on the med choice and individual factors obviously. I don’t actually know if there is an obvious choice for that type of weekly schedule 

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Zyprexa Zydis! I use it as a PRN, well I am about to start using it again. ANYWAY, it works fast because it’s zyprexa! Even faster because it melts in your mouth and not in your hands. It calms me if I’m agitated because of hearing a lot of crap voices and getting disturbing messages from the universe. 

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3 hours ago, Wonderful.Cheese said:

Zyprexa Zydis! I use it as a PRN, well I am about to start using it again. ANYWAY, it works fast because it’s zyprexa! Even faster because it melts in your mouth and not in your hands. It calms me if I’m agitated because of hearing a lot of crap voices and getting disturbing messages from the universe. 

OK, that was funny.

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I'd like to throw my favorite, Stelazine, on the table of possibilities. It's an oldie (a first-gen), but if taken prn for short periods of time, shouldn't be harmful, especially if the dose isn't too high. I love Stelazine because it reduces anxiety, depression, agitation, psychosis, tics, all that, while brightening my affect instead of flattening it like Haldol does.

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A PRN meds half life has a lot to do with whether it is an effective PRN med or not. Many of the AP/AAP's have very long half lives so it takes a while to get the full effect whereas AP's like Stelazine with a ~7 hour half life reach their peak in a more reasonable time, hours not days. Abilify never made it as a PRN med, with it's 75 hour half life and need to titrate to start off as to avoid side effects.

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